Cochliodone A is a bioactive compound derived from the deep-sea fungus Chaetomium sp., functioning primarily as an antibacterial agent. It demonstrates significant antibacterial activity, with minimal inhibitory concentrations (MICs) against various bacterial strains, including 15.3 μg/mL for V. vulnificus and 15.9 μg/mL for S. aureus ATCC 43300. Additionally, Cochliodone A exhibits anticancer properties, with IC50 values of 28.1 μM for A549, 20.7 μM for HeLa, and 23.2 μM for Hep G2 cancer cell lines, making it a valuable tool for pharmacological research.
Cochliodone A is a bioactive compound derived from the deep-sea fungus Chaetomium sp., functioning primarily as an antibacterial agent. It demonstrates significant antibacterial activity, with minimal inhibitory concentrations (MICs) against various bacterial strains, including 15.3 μg/mL for V. vulnificus and 15.9 μg/mL for S. aureus ATCC 43300. Additionally, Cochliodone A exhibits anticancer properties, with IC50 values of 28.1 μM for A549, 20.7 μM for HeLa, and 23.2 μM for Hep G2 cancer cell lines, making it a valuable tool for pharmacological research.
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