Catalog No.
Product Name
Application
Product Information
Citations
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HIV/HBV Inhibitor
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate, a phosphorylated metabolite of Emtricitabine. This compound functions as a nucleoside reverse transcriptase inhibitor, effectively targeting both HIV and HBV. Emtricitabine triphosphate tetrasodium salt is utilized in research applications focused on antiviral drug development and the mechanisms of viral replication. -
HIV Inhibitor
(S)-Tenofovir is an S-enantiomer of Tenofovir, functioning primarily as a nucleotide reverse transcriptase inhibitor. This compound demonstrates significant biological activity against HIV and is also relevant in the treatment of chronic Hepatitis B (HBV). It is commonly utilized in research applications focused on antiviral therapies and the mechanistic study of retroviral infections. -
Antiviral Agent
Helioxanthin is an antiviral agent with demonstrated in vitro activity, exhibiting an effective concentration (EC50) of 1 μM against hepatitis B virus (HBV). Additionally, Helioxanthin shows efficacy against flaviviruses, making it a valuable compound in antiviral research. It is suitable for studies focusing on the development of treatments for viral infections. -
HIV/HBV Inhibitor
L-Fd4A is an adenine derivative that inhibits both human immunodeficiency virus (HIV) and hepatitis B virus (HBV) with effective concentrations (EC50) of 1.5 μM and 1.7 μM, respectively. This compound demonstrates promising antiviral activity while exhibiting low cytotoxicity, making it suitable for research applications in studying HIV and HBV inhibition mechanisms. -
anti-HBV/HIV-1 Agent
Periglaucine A is a hasubanane-type alkaloid that targets anti-HBV and anti-HIV-1 activity. It effectively inhibits the secretion of HBV surface antigen (HBsAg) in Hep G2.2.15 cells, demonstrating its potential as a therapeutic agent against hepatitis B virus. Additionally, Periglaucine A exhibits anti-HIV-1 efficacy in C8166 cells, with an EC50 value of 204 μM, making it a valuable compound for research in viral infections. -
Antifolate Agent, Antibacterial Agent
11-Oxahomoaminopterin is an antifolate agent that inhibits dihydrofolate reductase, targeting bacterial and tumor cell proliferation. This compound exhibits significant antibacterial activity against Lactobacillus casei, demonstrating potential applications in antimicrobial and antitumor research. Its ability to interfere with folate metabolism makes it a valuable tool for studying various biological systems. -
Antibacterial Agent
Antibacterial Agent 330 is an antibacterial compound that operates by inducing reactive oxygen species (ROS) accumulation and forming supramolecular complexes through DNA intercalation, which inhibits DNA replication. This agent disrupts bacterial metabolism by inhibiting lactate dehydrogenase (LDH) and promotes cell lysis, resulting in the leakage of intracellular contents and bacterial cell death. Antibacterial Agent 330 demonstrates significant antibacterial activity and enhances wound healing in both Galleria mellonella larval and murine models, making it a valuable tool for researching bacterial infections. -
Antifungal Agent
Fluoxastrobin is an antifungal agent that targets NAD-dependent epimerase/dehydratase, inhibiting electron transport and reducing ATP production, which effectively controls foliar diseases in tea plants. This compound induces oxidative stress by elevating reactive oxygen species (ROS) levels and lipid peroxidation, leading to DNA damage and apoptosis. Additionally, Fluoxastrobin exhibits high acute toxicity to Danio rerio embryos and larvae, making it a valuable tool in research related to tea foliar diseases, including tea red leaf spot and tea gray leaf spot. -
Macropinocytosis inhibitor
Virapinib is a potent macropinocytosis inhibitor that demonstrates significant antiviral activity. It effectively inhibits viral entry of a broad range of viruses, including SARS-CoV-2, monkeypox virus, tick-borne encephalitis virus, and Ebola pseudotyped vesicular stomatitis virus, while also enhancing Dengue Virus infection. By obstructing macropinocytosis, Virapinib reduces syncytium formation in SARS-CoV-2-infected cells and hinders the cellular entry of SARS-CoV-2 variants. This compound is valuable for research focused on viral pathogenesis and therapeutic evaluations related to COVID-19 and other viral infections. -
SAR Inducer
3-Acetonyl-3-hydroxyoxindole functions as a potent systemic acquired resistance (SAR) inducer in plants. This compound has demonstrated the ability to enhance resistance in tobacco plants against the tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole also elevates levels of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation, and phenylalanine ammonia-lyase activity, making it a valuable tool for studying plant immune responses. -
TMV Inhibitor
TMV-IN-12 is a potent inhibitor of tobacco mosaic virus (TMV), targeting the aggregation and self-assembly of TMV capsid protein (TMV-CP) with a dissociation constant (Kd) of 0.142 μM. This compound effectively disrupts TMV particle formation, thereby preventing the infection of tobacco plants. Additionally, TMV-IN-12 exhibits antifungal properties, making it a valuable reagent for studying viral and fungal interactions in plant biology and for developing strategies to combat TMV-related diseases. -
Flaviviruse Inhibitor
Flaviviruses-IN-3 is a potent inhibitor specifically targeting flaviviruses. This compound demonstrates significant activity by reducing West Nile virus (WNV) protease activity, achieving an impressive inhibition rate of 54%. Flaviviruses-IN-3 is applicable for research into therapeutic strategies against flavivirus-related diseases and contributes to the understanding of viral protease functions. -
NS2B/NS3 Inhibitor
NS2B/NS3-IN-5 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue Virus Serotype 2 (DENV2) and Zika Virus (ZIKV). It demonstrates effective inhibitory activity with IC50 values of 0.67 µM against ZIKV and 4.38 µM against DENV2 NS2B/NS3 proteases. This compound presents significant potential for research applications in virology, specifically in the development of antiviral therapies targeting these flavivirus proteases. -
MTase Inhibitor
NSC 288387 is a pan-flavivirus methyltransferase (MTase) inhibitor that targets the S-adenosylmethionine (SAM) binding pocket. It demonstrates significant antiviral activity, inhibiting Zika virus (ZIKV) replication with an IC50 of 0.2 μM. This compound is useful in research applications focused on flavivirus infections and the mechanisms of viral replication. -
Flaviviruses Inhibitor
Flaviviruses-IN-2 is a potent inhibitor targeting flavivirus proteases, particularly effective against the West Nile virus (WNV). This compound significantly reduces WNV protease activity, achieving an inhibition level of 56%. Flaviviruses-IN-2 is primarily utilized in research applications focused on understanding flaviviral pathogenesis and developing antiviral therapeutics. -
NS2B/NS3 Inhibitor
NS2B/NS3-IN-4 is an allosteric inhibitor targeting the NS2B/NS3 protease of dengue virus serotype 2 (DENV2) and Zika virus (ZIKV). It demonstrates IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV proteases, highlighting its potent enzymatic inhibition. This compound serves as a valuable tool in antiviral research, particularly for elucidating mechanisms of viral replication and developing therapeutic strategies against flavivirus infections. -
NS2B/NS3 Inhibitor
NS2B/NS3-IN-6 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue virus (DENV) and Zika virus (ZIKV). It exhibits IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. This compound is valuable for research applications focused on developing antiviral therapies and understanding the enzymatic mechanisms of flavivirus proteases. -
HIV-1 Protease Inhibitor
(Rac)-PD 135390 is a potent HIV-1 protease inhibitor, exhibiting an IC50 of 2 nM. This dipeptide is instrumental in antiviral research, providing insights into HIV-1 protease activity and potential therapeutic interventions. Its efficacy in inhibiting viral replication makes it a valuable tool for studying HIV pathogenesis and drug resistance. -
DENV2 Inhibitor
YKL-04-085 is a potent inhibitor of dengue virus serotype 2 (DENV2) translation, demonstrating an IC90 of 0.555 μM. This compound specifically targets viral translation mechanisms, making it a valuable tool for research on DENV2 pathogenesis and antiviral drug development. Additionally, YKL-04-085 shows no kinase activity, allowing for more targeted investigations into its antiviral efficacy. -
Antibiotic
Cefamandole lithium is a second-generation broad-spectrum cephalosporin antibiotic that exerts its antibacterial activity by inhibiting bacterial cell wall synthesis. This compound is effective against a variety of Gram-positive and Gram-negative bacteria. Upon metabolism, cefamandole lithium releases free N-methylthiotetrazole (NMTT), which may result in low prothrombinemia, highlighting its importance in biochemical and pharmacological research applications. -
Antibiotic
Resorcinomycin A is an antibiotic primarily targeting mycobacterial species, demonstrating potent anti-mycobacterial activity. This compound exhibits weaker activity against mycoplasma, making it a valuable reagent for research applications focused on mycobacterial infections and mechanisms of action within this class of pathogens. -
Antitumor Antibiotic
IB-96212 is an antitumor antibiotic derived from the marine bacterium Micromonospora sp. It primarily targets cancer cells, demonstrating potent activity against the P-388 leukemia cell line. Additionally, IB-96212 exhibits antimicrobial properties against Micrococcus luteus, making it a valuable compound for various research applications in cancer and microbiology studies. -
Anti-Candidal Agent
Callophycin A is a natural metabolite derived from red seaweed, demonstrating strong antifungal activity against Candida albicans, with a minimum inhibitory concentration (MIC) of 62.5–250 mg/L. This compound effectively diminishes fungal load in models of vaginal candidiasis and is associated with reduced inflammatory responses and modulation of immune molecules. Callophycin A is valuable for research applications focusing on antifungal therapies and the immune responses associated withCandida infections. -
Antibiotic
A-83016F is an antibiotic compound with activity derived from an unidentified actinomycete designated A83016. This compound exhibits weak antimicrobial properties and is primarily used for research applications exploring antibiotic efficacy and microbial resistance mechanisms. Further investigation of A-83016F may provide insights into its potential therapeutic applications and bacteriologic interactions. -
Antibiotic
TS 155-2 is an antibiotic that acts as an analogue of Bafilomycin, functioning primarily through the inhibition of V-ATPase activity. This enzyme is critical for various cellular processes and has been associated with a range of diseases, including osteopetrosis, male infertility, and renal acidosis. TS 155-2 is valuable for research applications focusing on antimicrobial effects and the physiological roles of V-ATPase in disease contexts. -
Penicillin Antibiotic
Pivampicillin is a penicillin antibiotic that acts as a prodrug of ampicillin. Upon metabolism, it converts to ampicillin, exerting bactericidal activity against a broad range of Gram-positive and some Gram-negative bacteria. This compound is commonly utilized in research applications focused on studying bacterial infections and antibiotic resistance mechanisms. -
Antibiotic
Gentamicin C2 is an aminoglycoside antibiotic that targets bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits potent activity against a wide range of gram-negative bacteria, making it a valuable tool in microbial research and clinical applications. Gentamicin C2 is commonly utilized in studies investigating antibiotic resistance and the mechanisms of bacterial pathogenesis. -
Antibiotic
Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV is a potent antibiotic targeting bacterial protein synthesis. Its mechanism involves inhibiting the activity of the ribosomal machinery, leading to decreased protein production in susceptible bacteria. This compound is primarily utilized in research applications focused on antibiotic resistance and the development of novel antimicrobial therapies. -
Antibiotic
Phenelfamycin E is an elfamycin-type antibiotic that targets and exhibits activity against Gram-positive anaerobes, including Clostridium difficile. Its potent antibacterial properties make Phenelfamycin E a valuable tool for research applications focused on combating bacterial infections and studying antibiotic resistance mechanisms. -
Antibiotic
Formycin B is an antibiotic that primarily targets and exhibits antiparasitic activity against Leishmania species. It has been shown to induce cytotoxic effects on leukocytes, leading to a reversible decrease in neutrophil populations. This compound is valuable for research applications related to myeloid leukemia and can aid in the exploration of therapeutic pathways involving immune modulation. -
Antibiotic
Streptochlorin is an antibiotic compound with demonstrated antitrypanosomal activity, exhibiting an IC50 value of 230 ng/ml against the GUTat 3.1 strain. It is a valuable tool for research applications focused on the treatment of trypanosomiasis and the exploration of antibiotic mechanisms. -
Antibiotic
Setomimycin is a potent antibiotic that targets the SARS-CoV-2 main protease (Mpro) with an IC50 value of 12.02 µM. In addition to its antibacterial properties, Setomimycin exhibits anti-inflammatory and antioxidant effects. It also demonstrates significant antiproliferative and antitumor activity, making it a valuable reagent for research in infectious diseases and cancer biology. -
Antibiotic
Spergualin trihydrochloride is a naturally occurring antibiotic derived from the culture filtrates of Bacillus laterosporus BMG162-aF2. It exhibits significant antimicrobial activity, targeting a range of bacterial pathogens. This compound is utilized in research to explore antibiotic mechanisms and develop novel therapeutic strategies against bacterial infections. -
Antibiotic/Antimicrobial Peptide
Aurein 5.2 is an antimicrobial peptide with potent antibiotic properties. It exhibits broad-spectrum activity against various bacterial strains, making it a valuable tool in studies related to infection control and antibiotic resistance. Its mechanism of action involves disrupting bacterial cell membranes, leading to cell lysis. Aurein 5.2 is applicable in research focused on antimicrobial development and the understanding of peptide-based therapeutics. -
Antibiotic
TPU-0037A is an antibiotic that acts as a congener of lydicamycin, specifically targeting Gram-positive bacteria. It effectively inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, and Micrococcus luteus, with minimum inhibitory concentrations (MICs) ranging from 1.56 to 12.5 μg/mL. Notably, TPU-0037A shows no efficacy against Gram-negative strains such as Escherichia coli, Proteus mirabilis, Proteus vulgaris, or Pseudomonas aeruginosa, with MICs exceeding 50 μg/mL. This compound is valuable for research applications focused on antibiotic resistance and the mechanisms of bacterial growth inhibition. -
Antibacterial Agent
10-Decarbamoyloxy-9-dehydromitomycin B is a derivative of mitomycin with notable antibacterial properties. This compound exhibits significant antibacterial and antitumor activities, making it a valuable tool for research in infectious diseases and cancer treatment. Its mechanism of action involves DNA crosslinking, leading to inhibition of replication and cell division, thereby providing insights into therapeutic potential and resistance mechanisms. -
Antibiotic
Levonadifloxacin arginine hydrate is a broad-spectrum antibiotic targeting staphylococcal infections. It demonstrates significant antibacterial activity against both methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) strains. This compound is particularly effective in reducing bacterial load when phagocytized by THP-1 monocytes, making it a valuable tool for research in infectious diseases and antimicrobial resistance. -
Antibiotic
Chartreusin is an antibiotic that targets specific Gram-positive bacteria and mycobacteria. It demonstrates effective antimicrobial activity against various strains, including Micrococcus fiyogenes v. aureus phage. Chartreusin is primarily utilized in research applications focused on antibacterial properties and the development of novel therapeutic agents. -
Penem Antibiotic
FCE-25199 is a penem antibiotic with oral bioavailability that exhibits potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Its effectiveness in combating bacterial infections makes it a valuable tool for research in microbiology and infectious disease studies. This compound aids in the exploration of antibiotic resistance mechanisms and the development of new therapeutic strategies. -
Antibacterial Agents
Sulfachloropyridazine sodium is a sulfonamide antibiotic that exerts its antibacterial activity through the inhibition of bacterial folic acid synthesis. This compound is effective against a range of Gram-positive and Gram-negative bacteria, making it useful for research in antibiotic efficacy and resistance mechanisms. Its application includes studying bacterial growth inhibition and exploring the therapeutic potential in various infectious diseases. -
Antibiotic
3-O-Demethylfortimicin A is an aminocyclitol antibiotic that exhibits significant antibacterial activity. It is particularly effective against Gram-negative pathogens as well as Staphylococcus species. This compound can be utilized in research applications focusing on antibiotic resistance and the development of new antimicrobial therapies. -
Bacterial Inhibitor
FR-202306 is a bacterial inhibitor that targets peptide deformylase, an enzyme crucial for bacterial protein synthesis. This compound displays significant antibacterial activity against Staphylococcus aureus by effectively inhibiting its peptide deformylase activity. FR-202306 is valuable for research applications focused on developing antibacterial agents and exploring mechanisms of bacterial resistance. -
Bacterial Inhibitor
LF11 is a peptide that functions as a bacterial inhibitor by disrupting microbial cell membrane integrity. It exhibits potent antibacterial activity, making it a valuable tool for research focused on combating bacterial infections and studying antimicrobial mechanisms. Its application is particularly relevant in the development of new therapies and understanding resistance in pathogenic bacteria. -
antibiotic
Colistin B sulfate is an antibiotic derived from the soil bacterium Bacillus polymyxa. It primarily targets bacterial membranes, disrupting their integrity and leading to cell death. Colistin B sulfate is commonly used in research to study antibiotic resistance mechanisms and the effectiveness of antimicrobial therapies against Gram-negative bacteria. -
Antibiotic
Dactimicin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Derived from the bacterium Dactylosporangium matsuzakiense, it is part of the fortimicin antibiotic family. Dactimicin sulfate is valuable in research related to bacterial infections and can be used to investigate the effects on sensitive bacterial strains. Its unique structure and mechanism make it an important tool for studying antibiotic resistance and therapeutic applications. -
Antibiotic
Septamycin is a metal-complexing polyether antibiotic derived from the bacterium Streptomyces hygroscopicus NRRL 5678. This compound exhibits significant anticoccidial activity, making it useful in studying protozoan infections. Septamycin serves as a valuable reagent in research related to antibiotic development and the mechanisms of bacterial resistance. -
Antibiotic
Cinerubin B is a glycosylated anthracycline antibiotic that acts primarily as an anticancer agent. Derived from Streptomyces sp. SPB74, it exhibits significant cytotoxicity against a range of cancer cell lines. Cinerubin B is utilized in research for its potential therapeutic applications and to further understand its mechanism of action in cancer treatment. -
Antibacterial Agent
Antibacterial Agent 105 is a phenanthrolinic analog of quinolones that targets bacterial cell functions, demonstrating significant antibacterial activity against Mycobacterium tuberculosis with an MIC90 of 2.64 μM. This compound also exhibits broad-spectrum antibacterial efficacy against various bacterial species, including MIC90 values of 11.18 μM for M. smegmatis and M. aurum, 0.70 μM for M. marinum, 1.40 μM for BCG, 44.70 μM for Enterobacter aerogenes, and 22.35 μM for Staphylococcus aureus. Its diverse activity profile makes it a valuable tool for research in antimicrobial resistance and therapeutic interventions. -
Antibiotic
Cefalonium hydrate is a first-generation β-lactam cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It exhibits significant antibacterial activity against Gram-positive bacteria, making it an essential tool for research into bovine mastitis and related infections. This reagent is crucial for studying the efficacy of treatments and understanding the mechanisms of resistance in affected livestock. -
Antibiotic
Enterocin is an antibiotic that primarily targets gram-positive and certain gram-negative bacteria, exhibiting bacteriostatic activity. Due to its specificity, Enterocin shows no effectiveness against fungi and yeast. It is utilized in research applications focused on bacterial infections and the development of novel antimicrobial agents.
