Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Brilacidin tetrahydrochloride is a defensin mimetic antibiotic that exhibits potent antimicrobial activity against both Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MIC90) of 1 μg/mL against Streptococcus pneumoniae and 8 μg/mL against Streptococcus viridans, alongside MIC90 values of 8 μg/mL for Haemophilus influenzae and 4 μg/mL for Pseudomonas aeruginosa. This compound is particularly valuable in microbiological research and the development of novel therapeutic strategies for bacterial infections. -
Antibiotic
Ertapenem disodium is a broad-spectrum β-lactam antibiotic known for its long-lasting activity against a wide range of pathogens. It exhibits significant anti-anaerobic efficacy, with a minimum inhibitory concentration (MIC) of 0.12 μg/mL against various anaerobic bacteria. This reagent is particularly useful in research focused on severe infections affecting the skin, lungs, stomach, pelvis, and urinary tract. -
Antibiotic
SPR206 acetate is a polymyxin analog that exhibits potent antibiotic activity against Gram-negative pathogens, including multidrug-resistant strains. Its mechanism involves disrupting the outer membrane of bacteria, leading to bactericidal effects. SPR206 acetate demonstrates low minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301, making it a valuable tool in the study of bacterial infections and antibiotic resistance. -
Bacteriostatic Antibiotic
Trimethoprim lactate is a bacteriostatic antibiotic that functions as a dihydrofolate reductase inhibitor. It exhibits activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, making it valuable in research related to urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim lactate has been shown to inhibit Influenza A virus infection in chick embryos when used in combination with zinc. -
Bacteriostatic Antimycobacterial Agent
Ethambutol dihydrochloride is a bacteriostatic antimycobacterial agent that inhibits the activity of arabinosyltransferase, thereby preventing cell wall synthesis in Mycobacterium species. This compound is primarily utilized in research to study tuberculosis and other mycobacterial infections, as well as to establish animal models for hyperuricemia and optic neuropathy. Its mechanism and applications make it an important tool for investigating various microbial pathologies and associated therapeutic strategies. -
Bacterial Biofilm Formation Inhibitor
Ethyl acetoacetate is an ester compound that acts as an inhibitor of bacterial biofilm formation. Its unique chemical structure facilitates its role in impairing the ability of bacteria to adhere and form protective biofilms, making it a valuable research tool in studying microbial resistance and infection control. This reagent is useful in various biological applications, particularly in investigations aimed at understanding bacterial behavior and developing new antimicrobial strategies. -
Antibiotic
Cefuroxime is a second-generation cephalosporin antibiotic that exerts its effects through inhibition of bacterial cell wall synthesis. It demonstrates a broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria while exhibiting enhanced stability to β-lactamase enzymes. Cefuroxime is widely utilized in research applications aimed at studying bacterial infections and antibiotic resistance. -
Aminoglycoside Antibiotic
Amikacin sulfate is an aminoglycoside antibiotic and a semisynthetic derivative of kanamycin, primarily targeting bacterial ribosomal subunits 30S and 50S to inhibit protein synthesis. This compound exhibits potent bactericidal activity against a wide range of Gram-negative bacteria, including strains resistant to gentamicin and tobramycin. Additionally, amikacin sulfate is effective against infections caused by susceptible Nocardia and nontuberculous mycobacteria, making it valuable in various microbiological research applications. -
Antibiotic
Colominic acid sodium salt is a polysaccharide derived from the cell wall of Escherichia coli and various animal sources. This compound exhibits antibacterial activity and is characterized by a distinctive red color, with an absorption maximum at 530 nm. It serves as a valuable tool in microbiological research, particularly for studying bacterial interactions and polysaccharide functions in biological systems. -
Antibacterial Antibiotic
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic that targets bacterial cell wall synthesis. It exhibits significant antibacterial activity against a variety of gram-positive and gram-negative organisms. Although effective, it is important to note that cephaloridine has been associated with dose-related nephrotoxicity, which should be considered in experimental applications. -
Antibiotic
Plazomicin sulfate is a semi-synthetic aminoglycoside antibiotic that primarily targets bacterial ribosomes to disrupt protein synthesis. It functions as a substrate for aminoglycoside acetyltransferase and aminoglycoside phosphotransferase while remaining unmodified by several common aminoglycoside-modifying enzymes. Plazomicin sulfate exhibits selective inhibition of MATE2-K and demonstrates significant efficacy against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales. This compound is valuable for research applications focusing on antibiotic resistance and the mechanisms of action of aminoglycosides. -
Antibiotic
Dalfopristin is a semisynthetic sulfone antibiotic that functions by inhibiting bacterial protein synthesis. Although Dalfopristin exhibits limited antibacterial activity on its own, it demonstrates significant bactericidal effects in synergy with Quinupristin, particularly against a range of pathogenic Gram-positive cocci. This compound is utilized in research focused on antibiotic resistance and the development of combination therapies for bacterial infections. -
Antibiotic
Cefquinome sulfate is a broad-spectrum cephem antibiotic that targets bacterial cell wall synthesis, effectively inhibiting a wide range of Gram-positive and Gram-negative bacteria. Its antibacterial activity extends to species such as Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae. Cefquinome sulfate is primarily used in veterinary medicine for the treatment of bacterial infections, making it a valuable tool in microbiological research and antibiotic susceptibility studies. -
Antibiotic
SPR741 is a cationic peptide antibiotic derived from polymyxin B, functioning primarily as a potentiator. It enhances the permeability of the outer membrane in Gram-negative bacteria, making it an effective agent against multidrug-resistant strains. SPR741 is utilized in research focused on severe Gram-negative infections and can broaden the spectrum of activity when used in combination with other antibiotics. -
Antibiotic
Nalidixic acid sodium salt is a quinolone antibiotic targeting DNA gyrase and topoisomerase IV. It exhibits bacteriostatic activity at lower concentrations and becomes bactericidal at higher concentrations, effectively inhibiting DNA replication in susceptible gram-positive and gram-negative bacteria. This compound is valuable for microbiological research and antibiotic susceptibility testing, facilitating the study of bacterial infections and resistance mechanisms. -
Antibacterial Agent
Colistin methanesulfonate sodium salt is an antibacterial agent that primarily targets Gram-negative bacteria, including Pseudomonas aeruginosa. It demonstrates minimum inhibitory concentration (MIC) values ranging from 4 to 16 mg/L against susceptible strains, making it an essential compound for research in antimicrobial resistance and the efficacy of antibiotic treatments. This reagent is suitable for studies requiring a focus on antibiotic susceptibility and the mechanisms of action of colistin derivatives. -
Antibiotic
Nosiheptide is a thiopeptide antibiotic that targets bacterial protein synthesis. It is produced by Streptomyces actuosus and features a unique indole side ring system along with regiospecific hydroxyl groups on its macrocyclic core. Nosiheptide is utilized in research applications focused on antimicrobial activity and has also been used as a feed additive to promote animal growth. -
Antibiotic
Lefamulin acetate is an orally active antibiotic that targets bacterial protein synthesis by binding to the peptidyl transferase center of the 50S ribosomal subunit. This mechanism disrupts bacterial growth and has been shown to possess anti-inflammatory properties. Lefamulin acetate is applicable in research focused on bacterial infections, including those caused by pneumonia-inducing pathogens. -
Antibacterial Agent
Pectin is a heteropolysaccharide primarily derived from the cell walls of higher plants, functioning as an effective antibacterial agent. It exhibits broad-spectrum antimicrobial activity, binding to bacterial toxins and irritants in the intestinal mucosa, thereby alleviating mucosal irritation. Additionally, pectin serves as a versatile agent for the formation of nanoparticles, facilitating the delivery of therapeutic compounds. Its properties make it valuable for research in gastrointestinal health and drug delivery systems. -
Antibiotic
Virginiamycin M1 is a polyunsaturated macrocyclic lactone antibiotic derived from Streptomyces virginiae. It exhibits significant antibacterial activity against Staphylococcus aureus, with a minimal inhibitory concentration (MIC) of 0.25 μg/mL. This compound is commonly utilized in research applications to investigate antibiotic mechanisms and resistance, as well as for the study of bacterial pathogens. -
Antibiotic
Framycetin sulfate, an aminoglycoside antibiotic, primarily targets RNase P, functioning as a potent inhibitor of its cleavage activity with a Ki of 35 μM. It competes for divalent metal ion binding sites within RNase P RNA, effectively inhibiting the hammerhead ribozyme with a Ki of 13.5 μM. Additionally, as a 5″-azido neomycin B precursor, Framycetin sulfate binds to the Drosha site in miR-525, making it applicable in the study of hepatic encephalopathy and enteropathogenic E. coli infections. -
Antibiotic
Nemadectin is an orally active broad-spectrum endectocide that targets gastrointestinal helminths. It demonstrates potent anthelmintic activity, making it effective against natural infections in canines caused by major helminth species. This compound is valuable for research applications focused on parasitic infections and the development of novel anthelmintic therapies. -
Antibiotic
Kanamycin sulfate is a broad-spectrum aminoglycoside antibiotic that primarily targets bacterial protein synthesis by binding to the 30S ribosomal subunit. This reagent is effective against a range of bacterial infections, particularly those caused by certain staphylococci and Gram-negative bacilli. However, caution is advised due to its potential ototoxic effects. Kanamycin sulfate is commonly utilized in microbiological research and treatment protocols for severe bacterial infections. -
Antibiotic
Cefpodoxime is a broad-spectrum antibiotic that exhibits activity against a variety of gram-positive and gram-negative bacteria. Its primary mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Cefpodoxime is useful for research applications related to acute otitis media, sinusitis, and tonsillopharyngitis, enabling investigations into microbial resistance and treatment efficacy. -
Tetracycline Antibiotic
Demeclocycline is an orally active tetracycline antibiotic that targets bacterial protein synthesis. It functions by binding to the 30S ribosomal subunit, effectively inhibiting the binding of aminoacyl-tRNA. Demeclocycline demonstrates antibacterial activity against a broad spectrum of bacterial infections and is utilized in various research applications related to antibiotic resistance and microbial pathogenesis. -
Antibiotic
Gentamicin C1a is an aminoglycoside antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. As the major component of the Gentamicin complex, it exhibits significant antibacterial activity against a wide range of Gram-negative and some Gram-positive bacteria. Gentamicin C1a is commonly employed in microbiological research and clinical studies to evaluate antibacterial efficacy and resistance mechanisms. -
Antibiotic Agent
Cloxacillin sodium is a β-lactam antibiotic and a potent β-lactamase inhibitor with an IC50 of 0.04 µM. It exhibits significant antibacterial activity, particularly against Staphylococcus aureus, and can effectively attenuate the S. aureus-induced inflammatory response by inhibiting the activation of MAPK, NF-κB, and NLRP3-related proteins. This compound is relevant for research in antimicrobial resistance and inflammation pathways. -
Antibiotic
Lefamulin is an orally active antibiotic that primarily targets bacterial protein synthesis by binding to the peptidyl transferase center of the 50S ribosomal subunit. This binding effectively inhibits the formation of peptide bonds, leading to disruption of bacterial growth. In addition to its antimicrobial properties, Lefamulin exhibits anti-inflammatory activity. It is valuable for research applications focused on bacterial infections, including conditions such as bacterial pneumonia. -
Antibiotic
Amoxicillin-clavulanate potassium is a combination antibiotic that targets bacterial cell wall synthesis and inhibits beta-lactamase enzymes. It exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative pathogens. This reagent is commonly utilized in research to study bacterial infections and evaluate potential therapeutic strategies for combating antibiotic resistance. -
Antibiotic
Contezolid is an orally active oxazolidinone antibiotic targeting resistant Gram-positive bacteria. It demonstrates significant efficacy against complicated skin and soft tissue infections (cSSTI) while exhibiting a reduced risk of myelosuppression and minimal monoamine oxidase inhibition. This unique profile makes Contezolid a promising candidate for the treatment of infections caused by resistant strains. -
Antibacterial Agent
Ceftolozane is a cephalosporin antibiotic that specifically targets bacterial infections by inhibiting cell wall synthesis. It exhibits potent antibacterial activity against Pseudomonas aeruginosa and various Enterobacteriaceae strains, with minimal inhibitory concentrations (MICs) reported at 0.5 mg/L and 0.25-0.5 mg/L, respectively. This reagent is valuable for research applications focused on antibiotic resistance and the development of new therapeutic strategies. -
Antibiotic
Mupirocin lithium is an antibiotic that targets bacterial isoleucyl-tRNA synthetase, effectively inhibiting protein synthesis. This compound exhibits potent activity against a range of Gram-positive bacteria, including Staphylococcus and Streptococcus, as well as certain Gram-negative strains such as Haemophilus influenzae. Mupirocin lithium is utilized in research focused on skin infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA), and chronic sinusitis. -
Antibiotic
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic that targets gram-positive bacteria. Derived from Actinoplanes species, it exhibits potent antimicrobial activity, making it effective against various resistant strains. This compound is significant for research applications focusing on antibiotic resistance mechanisms and the development of novel antimicrobial therapies. -
Antibiotic
Hygromycin A is a spirochete-specific antibiotic targeting Borrelia burgdorferi, the causative agent of Lyme disease. It exhibits potent antibacterial activity against spirochetes, making it a valuable tool for research into Lyme disease and gut health. Hygromycin A is suitable for studies investigating spirochete pathogenesis and potential therapeutic interventions. -
Antibiotic
Cefetamet is a cephalosporin antibiotic that functions by binding to bacterial penicillin-binding proteins (PBPs), with an IC50 of 2.5 μg/mL for PBP3 in Escherichia coli W3110. It exhibits significant antibacterial activity against a variety of Gram-negative bacteria, including Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Additionally, Cefetamet demonstrates bactericidal effects against Treponema pallidum. This compound is valuable for researching respiratory, urinary, and ear, nose, and throat infections, in addition to syphilis. -
Antibiotic Agent
Oxytetracycline hydrochloride is an antibiotic from the tetracycline class, primarily targeting bacterial protein synthesis. It effectively inhibits both Gram-negative and Gram-positive bacteria by preventing the binding of aminoacyl-tRNA to the mRNA-ribosomal RNA complex. Additionally, oxytetracycline hydrochloride exhibits anti-HSV-1 activity, making it valuable for research applications in microbiology and virology. -
Polypeptide Antibiotic
Colistin is a polypeptide antibiotic primarily targeting Gram-negative bacteria. It demonstrates potent activity against multidrug-resistant strains such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. Due to its nephrotoxic potential, careful consideration is required during research. Colistin is valuable for studying infections caused by Gram-negative bacilli and exploring antibiotic resistance mechanisms. -
Antibiotic
Penicillin V, also known as Phenoxymethylpenicillin, is a potent, orally bioavailable antibiotic targeting bacterial cell wall synthesis. It exhibits significant antibacterial activity against Streptococci, Clostridium difficile, and Staphylococcus aureus. This compound is valuable for research applications related to otitis, sinusitis, pharyngitis, and tonsillitis, providing insights into bacterial pathogenesis and resistance mechanisms. -
Antibiotic
Cefacetrile is a broad-spectrum antibiotic with activity against both gram-positive and gram-negative bacteria. It targets bacterial cell wall synthesis, inhibiting peptidoglycan cross-linking, which leads to cell lysis and death. This compound is primarily utilized in research involving bacterial infections and offers valuable insights into antibiotic mechanisms and resistance. -
Lipoglycopeptide Antibiotic
Dalbavancin is a semisynthetic lipoglycopeptide antibiotic targeting Gram-positive bacteria. It exhibits potent bactericidal activity, with minimal inhibitory concentrations (MIC90) of 0.06 μg/mL against Staphylococcus aureus and 0.25 μg/mL against Bacillus anthracis. This compound is primarily utilized in research applications focused on bacterial infections and the development of novel antimicrobial therapies. -
Antibiotic
Micronomicin is an aminoglycoside antibiotic that exerts its effects primarily by binding to bacterial ribosomal RNA, leading to disruption of protein synthesis. This compound exhibits significant antibacterial and bactericidal activity against a wide range of Gram-negative and some Gram-positive bacteria. Micronomicin is utilized in research applications related to antibiotic resistance, infection models, and the study of microbial pathogenesis. -
Antibiotic
Telavancin hydrochloride is an antibiotic that functions primarily by inhibiting cell wall synthesis and disrupting cell membrane barrier function. This semisynthetic derivative of vancomycin demonstrates significant antibacterial activity against antibiotic-resistant Staphylococcus aureus strains, including MRSA, VISA, and hVISA. Telavancin hydrochloride is particularly effective in treating complicated skin and skin structure infections (cSSSI) caused by gram-positive bacteria. This compound is valuable for research into antibiotic resistance and the development of novel antimicrobial therapies. -
Antibacterial Agent
Thiocarlide is an effective antibacterial agent primarily targeting Mycobacterium species. It demonstrates significant inhibitory activity against Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG, Mycobacterium avium, and Mycobacterium aurum A+, with minimum inhibitory concentrations (MICs) of 2.5, 0.5, 2.0, and 2.0 μg/mL, respectively. Thiocarlide can be utilized in research applications focused on tuberculosis and other mycobacterial infections. -
Lincosamide Antibiotic
Lincomycin is a lincosamide antibiotic that targets bacterial protein synthesis by inhibiting the 50S ribosomal subunit. It exhibits potent antimicrobial activity against a range of Gram-positive bacteria, making it invaluable in studying bacterial infections and resistance mechanisms. Lincomycin is commonly used in research applications focusing on microbial pathogenesis and the development of antibiotic resistance. -
Antibiotic
Djalonensone is an antibiotic compound isolated from the roots of Anthocleista djalonensis (Loganiaceae). It exhibits significant antimicrobial activity, making it a valuable tool in research focused on developing new antibiotic therapies. Its unique properties also serve as an important taxonomic marker for the identification and classification of this plant species. -
Antibiotic
Bleomycin B4 is an antibiotic that exhibits potent antitumor activity. It functions by inducing DNA strand breaks, leading to cell cycle arrest and apoptosis in cancer cells. This compound is commonly utilized in cancer research to explore therapeutic strategies and mechanisms of action in oncology. -
Antibacterial Agent
Cyclacillin is an orally active aminopenicillin antibiotic that primarily targets bacterial cell wall synthesis. It exhibits significant antibacterial activity against a broad spectrum of gram-positive and gram-negative pathogens. This compound is useful in research applications focused on infection models and the study of antibiotic resistance mechanisms. -
Antibiotic
Enduracidin is a polypeptide antibiotic that exerts its antibacterial effects by inhibiting cell wall synthesis in susceptible bacteria. Originally derived from Streptomyces fungicides, this compound is effective against a range of Gram-positive organisms. Enduracidin is primarily utilized in research applications focused on antibiotic resistance and the development of novel antibacterial agents. -
Antibacterial Agent
Tellimagrandin II is an antibacterial agent that disrupts the integrity of the cell wall in Staphylococcus aureus, leading to cell lysis and loss of cytoplasmic contents. Additionally, it demonstrates anti-inflammatory properties and inhibits acetylcholinesterase (AChE), which may contribute to improvements in memory impairment. This compound is of interest in research focusing on antibacterial strategies, inflammatory pathways, and neurodegenerative conditions. -
Antibiotic
Kasugamycin is an antibiotic that targets the ribosomal subunits by binding to both the 30S and 70S ribosomes, without interacting with isolated 50S subunits. It mimics mRNA nucleotides, leading to destabilization of tRNA binding and inhibition of canonical translation initiation. This compound is valuable for research in antibiotic mechanisms, ribosomal function, and the study of bacterial protein synthesis.
