Catalog No.
Product Name
Application
Product Information
Citations
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GAK Inhibitor
GAK Inhibitor 2 is a selective inhibitor of cyclin G-associated kinase (GAK), exhibiting a potent IC50 value of 0.024 μM. This compound demonstrates significant antiviral activity, with an effective concentration (EC50) of 1.049 μM against dengue virus (DENV). GAK Inhibitor 2 is suitable for research exploring GAK's role in viral pathogenesis and therapeutic strategies against DENV. -
Cephalosporin Antibiotic
Cephalexin hydrochloride is a semisynthetic cephalosporin antibiotic that exhibits potent activity against a broad spectrum of gram-positive and gram-negative bacteria. It acts primarily by targeting penicillin-binding proteins (PBPs), leading to the inhibition of bacterial cell wall synthesis. This compound is commonly utilized in research related to bacterial infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. -
Antibiotic
Hordenine hydrochloride is an alkaloid known for its antibiotic properties and its mechanism of action involves the inhibition of melanogenesis through the suppression of cyclic adenosine monophosphate (cAMP) production. This compound is of significant interest in research focused on skin biology and pigmentation processes. Additionally, hordenine hydrochloride may be explored for its potential therapeutic applications in various dermatological conditions. -
Veterinary Antibiotic
Nifursol is an orally active veterinary antibiotic that targets Histomonas meleagridis, effectively preventing histomoniasis in turkeys. This agent is utilized in research focused on Escherichia coli gastroenteritis, particularly in the context of Salmonella infections in poultry and aquatic animals. Its application in veterinary medicine supports studies investigating antibiotic efficacy and disease prevention in livestock. -
Antibiotic
trans-Clopenthixol is an antibiotic that exhibits no neuroleptic effects. It has demonstrated the ability to inhibit the growth of Pseudomonas aeruginosa and Plasmodium falciparum in vitro. This compound may be valuable for research applications focused on bacterial and parasitic infections. -
Aminoglycoside Antibiotic
Neamine tetrahydrochloride is an aminoglycoside antibiotic that exhibits broad-spectrum antibacterial activity. It serves as an anti-angiogenesis agent by specifically targeting angiogenin, contributing to its antitumor properties. Additionally, Neamine tetrahydrochloride demonstrates neuroprotective effects, making it valuable in various biomedical research applications, including studies focused on cancer and neurodegenerative diseases. -
Cephalosporin Antibiotic
Ceftaroline fosamil hydrate is a potent cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum efficacy against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, as well as common Gram-negative bacteria. This compound is valuable for research focused on complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP). -
Antibiotic
Ribostamycin is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis, primarily by binding to the ribosome. It exhibits activity against both Gram-negative and Gram-positive bacterial infections. Additionally, Ribostamycin has been shown to inhibit the chaperone activity of protein disulfide isomerase (PDI), making it useful in various research applications related to microbial resistance and protein folding studies. -
Antibiotic
Nybomycin is an antibiotic that demonstrates significant antiphage and antibacterial activity. It functions by binding to DNA, resulting in distinctive morphological alterations in mycobacterial bacilli, ultimately leading to bacterial cell death. This compound is valuable in research applications focused on understanding bacterial resistance and developing new antimicrobial therapies. -
Cephalosporin Antibiotic
Cefteram pivoxil is an orally active cephalosporin antibiotic that targets bacterial cell wall synthesis. Its primary mechanism involves the inhibition of penicillin-binding proteins, leading to bacterial lysis and death. This compound exhibits broad-spectrum antibacterial activity and is commonly utilized in the treatment of various bacterial infections, including respiratory and urinary tract infections. -
Bacterial Inhibitor
Moxifloxacin hydrochloride monohydrate is a potent bacterial inhibitor that targets DNA gyrase and topoisomerase IV, leading to the disruption of bacterial DNA replication and transcription. It exhibits strong efficacy against Streptococcus pneumoniae and is primarily utilized in the study of bacterial infections, including research on tuberculosis. Its oral bioavailability and broad-spectrum activity make it a valuable reagent for microbiological studies and antibiotic efficacy testing. -
Cephamycin Antibiotic
Cefmetazole is a semisynthetic cephamycin antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall biosynthesis. With broad-spectrum antibacterial activity, it effectively combats gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole is commonly utilized in research focused on gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections. -
Antibiotic
Alafosfalin is a phosphonodipeptide that functions as an inhibitor of cell wall biosynthesis. It exhibits antibacterial activity, making it a valuable tool for research in the study of bacterial infections and the mechanisms of antibiotic resistance. This compound is applicable in investigations focusing on cell wall integrity and the development of novel antibacterial strategies. -
Antibiotic
Cefixime trihydrate is a third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum activity against various gram-positive and gram-negative bacteria, making it effective for treating a range of bacterial infections, including urinary tract infections and respiratory tract infections. This compound is valuable in microbiological research and the study of antibiotic resistance mechanisms. -
Bacterial Inhibitor
Helvolic acid, also known as Fumigacin, is a natural antibiotic derived from Xylaria sp. It exhibits potent activity against Gram-positive bacteria, making it a valuable tool for investigating bacterial inhibition. This compound can be utilized in microbiological studies to explore mechanisms of antibiotic action and resistance. -
Antibiotic
Fluoroquinolonic acid is a bacteriostatic antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV. This compound demonstrates broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, making it useful in various microbiological studies. Its ability to inhibit bacterial growth positions it as a valuable reagent for research applications in antibiotic resistance and pathogen profiling. -
Lipopeptide Antibiotic
Globomycin is a lipopeptide antibiotic that acts as an irreversible inhibitor of signal peptidase II (LspA). By binding to the peptidase, Globomycin disrupts the processing of prolipoproteins, demonstrating significant antibacterial activity against the mollicute Spiroplasma melliferum with a minimum inhibitory concentration (MIC) of 6.25-12.5 μM. This compound is valuable for research applications focused on bacterial protein processing and antibiotic resistance mechanisms. -
Antibiotic
AMOZ-d5 is a deuterated form of AMOZ, a tissue-bound metabolite of the synthetic nitrofuran antibiotic Furaltadone. This compound exhibits potent antibacterial activity and is primarily utilized in research to study the pharmacokinetics and metabolism of nitrofuran antibiotics. Its stable isotopic labeling allows for detailed analytical investigations in various biological samples. -
Chloramphenicol-Like Antibiotic
Azidamfenicol is a chloramphenicol-like antibiotic that functions by inhibiting ribosomal peptidyltransferase with a Ki value of 22 μM. This broad-spectrum agent exhibits significant antibacterial activity, making it useful in studying bacterial protein synthesis. Additionally, Azidamfenicol serves as a click chemistry reagent due to the presence of an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. This dual functionality allows for versatile applications in chemical biology and bioconjugation strategies. -
Antibiotic
Mellein is an antibiotic derived from the culture fluids of Aspergillus species. This compound exhibits potent antibacterial activity, making it valuable in studying microbial resistance and the mechanisms of action of antibiotics. Its application extends to various fields of microbiological research and drug development, providing insights into potential therapeutic uses. -
Antibiotic
Cefalonium is a first-generation β-lactam cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits potent activity against Gram-positive bacteria, particularly staphylococci, making it a valuable tool for studying bovine mastitis. This compound is essential for research applications focused on bacterial infections and antibiotic resistance mechanisms in veterinary medicine. -
Antibiotic
Ulifloxacin is a broad-spectrum quinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. It demonstrates potent antibacterial activity against a variety of Gram-positive and Gram-negative pathogens. Due to its efficacy, Ulifloxacin is utilized in research applications focused on infectious diseases and the development of novel antibacterial therapies. -
HIV-1 Inhibitor
Formycin A is a purine nucleoside antibiotic that acts as a potent inhibitor of human immunodeficiency virus type 1 (HIV-1), exhibiting an EC50 of 10 μM. This compound demonstrates notable antiviral and antitumor activities, making it a valuable tool for research in virology and cancer biology. Its efficacy against HIV-1 makes it a relevant candidate for studies aimed at developing antiviral therapies. -
β-lactam Antibiotic
Azidocillin is a semi-synthetic β-lactam antibiotic that exhibits oral bioavailability and retains its antibacterial activity against various pathogens. Featuring an azide group, Azidocillin serves as both a therapeutic agent and a versatile click chemistry reagent, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds. It may also undergo strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups. This compound is valuable for investigating osteitis resulting from dental procedures, otitis media, enterococcal septicemia, and other bacterial infections. -
Antibiotic Agent
Metronidazole acetic acid is a metabolite of metronidazole that exhibits mutagenic activity in bacterial systems. As a nitroimidazole antibiotic, it is effective against anaerobic bacteria and protozoa, making it valuable for research in antimicrobial resistance and infectious disease models. Its unique properties allow for exploration of mutagenesis and metabolism in microbial contexts, supporting various biochemical studies. -
Antibiotic
Penicillin G benzathine tetrahydrate is a beta-lactam antibiotic that functions by inhibiting bacterial cell wall synthesis. It possesses potent activity against a wide range of Gram-positive bacteria, making it effective in treating various bacterial infections, including rheumatic fever and syphilis. This compound is commonly utilized in clinical and research settings to study antibiotic resistance and the pharmacokinetics of penicillin derivatives. -
Antibiotic
Aurachin SS is an antibiotic compound derived from the natural product isolated from Streptomyces sp. NA04227. It exhibits significant antibacterial activity, making it a valuable tool for research into microbial resistance and the development of new antimicrobial strategies. This compound is suitable for investigations in microbiology and therapeutic applications targeting bacterial infections. -
Macrolide Antibiotic
Erythromycylamine is a macrolide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. It exhibits significant antibacterial activity against a range of Gram-positive cocci and Moraxella catarrhalis. This reagent is valuable for research applications focusing on bacterial resistance, antibiotic efficacy studies, and the mechanisms of action of macrolide antibiotics. -
Antibacterial Agent
SABA1 is an antibacterial agent that exhibits significant activity against Pseudomonas aeruginosa and Escherichia coli. With an IC50 of 4.0 µM against E. coli ACC, SABA1 is a valuable tool for researching bacterial infections and antimicrobial resistance in various biological studies. -
Glycopeptide Antibiotic
Chloroorienticin A is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by targeting the transglycosylation activity in gram-positive bacteria. This compound demonstrates potent antibacterial activity against staphylococci and streptococci, making it a valuable tool for research on antibiotic resistance and bacterial pathogenesis. Its efficacy in inhibiting the growth of these pathogens supports its use in studying the mechanisms of antibiotic action and resistance development in clinical strains. -
Antibiotic
Benapenem is a carbapenem antibiotic that functions by inhibiting bacterial cell wall synthesis through its action on penicillin-binding proteins. This broad-spectrum β-lactam agent is effective against both Gram-positive and Gram-negative bacteria, making it suitable for treating various bacterial infections. Its applications extend to research on antibiotic resistance and the development of novel antimicrobial therapies. -
Antibacterial Agent
Mafenide is a sulfonamide-type antimicrobial agent that primarily targets bacterial nucleotide synthesis. It exhibits potent antibacterial activity against a broad spectrum of pathogens, including both Gram-positive and Gram-negative bacteria, such as Pseudomonas aeruginosa. Mafenide is commonly utilized in research related to wound healing and the treatment of burn injuries, due to its effective antimicrobial properties. -
Glycopeptide Antibiotic
Phleomycin D1 is a glycopeptide antibiotic that targets DNA. It exerts its biological activity by binding to and cleaving DNA, leading to cell death. Additionally, Phleomycin D1 induces cell cycle arrest at the S phase, making it a valuable reagent for research applications in cancer biology and molecular genetics. -
Antibacterial Agent
Gepotidacin mesylate hydrate is an orally active antibiotic that functions as a bacterial type II topoisomerase inhibitor. It interferes with bacterial DNA replication by obstructing topoisomerase enzymes, specifically targeting topoisomerase IV and the B subunit of DNA gyrase. This compound is primarily used in research applications investigating antibacterial mechanisms and the development of novel antimicrobial agents. -
Antibiotic
Actinorhodin is a redox-active microbial secondary metabolite known for its potent antibacterial properties. This blue-pigmented compound functions as a bacteriostatic antibiotic, displaying significant activity against Gram-positive bacteria. Actinorhodin's pH-responsive nature enhances its utility in various research applications, particularly in studies focused on microbial resistance and antibiotic efficacy. -
Cephalosporin Antibiotic
Ceftaroline fosamil (inner) is a cephalosporin antibiotic that acts as an N-phosphono proagent effective against methicillin-resistant Staphylococcus aureus (MRSA). This reagent demonstrates significant antibacterial activity, making it a valuable tool in the study of MRSA infections and antibiotic resistance mechanisms. Its application extends to research aimed at developing new therapeutic strategies for combating resistant bacterial strains. -
Antibiotic Agent
Oxytetracycline calcium is a broad-spectrum antibiotic that targets bacterial protein synthesis. It effectively inhibits the binding of aminoacyl-tRNA to the mRNA-ribosomal complex, demonstrating potent activity against both Gram-negative and Gram-positive bacteria. Additionally, Oxytetracycline calcium exhibits antiviral properties, specifically against herpes simplex virus type 1 (HSV-1). This compound is widely utilized in microbiological research and for studying bacterial resistance mechanisms. -
Ephalosporin Antibiotic
Cephapirin is a cephalosporin antibiotic that exhibits broad-spectrum antimicrobial activity by inhibiting bacterial cell wall synthesis. This compound is effective against both Gram-positive and some Gram-negative bacteria, making it valuable in various clinical applications. It is commonly used in research to study antibiotic resistance and evaluate the efficacy of antimicrobial agents. -
Antibiotic
Contezolid acefosamil sodium is an orally active oxazolidinone antibiotic targeting resistant Gram-positive bacteria. It demonstrates significant efficacy in treating complicated skin and soft tissue infections (cSSTI). Notably, this compound exhibits a reduced risk of myelosuppression and minimizes monoamine oxidase inhibition, enhancing its safety profile in clinical applications. -
Antibiotic
Nafcillin is a β-lactam antibiotic that functions as a reversible inhibitor of β-lactamase. It demonstrates potent bactericidal activity against penicillin-resistant strains, particularly Staphylococcus aureus. Nafcillin is commonly utilized in research focused on staphylococcal infections, contributing to the understanding and treatment of resistant bacterial strains. -
Antibiotic
Mycaminosyltylonolide is a potent antibiotic that targets bacterial pathogens. It exhibits significant antibacterial activity by inhibiting luciferase synthesis, disrupting essential bacterial processes. This compound is valuable for research applications focused on antibacterial mechanisms and the development of new therapeutic strategies against resistant bacterial strains. -
Calcium Ionophore Antibiotic, Methanogenic Bacteria Inhibitor
Chlortetracycline is a calcium ionophore antibiotic that primarily targets bacterial protein synthesis by inhibiting the binding of aminoacyl-tRNA to ribosomes. This compound demonstrates potent bactericidal activity and serves as a selective inhibitor of methanogenic bacteria. Chlortetracycline is widely utilized in research applications involving antibiotic resistance studies and metabolic pathway investigations in anaerobic organisms. -
Antibiotic
Carbomycin B is a macrolide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. Its potent antibacterial activity makes it effective against a variety of Gram-positive bacteria. Carbomycin B is commonly utilized in microbiological research to study antibiotic resistance mechanisms and explore new therapeutic strategies. -
Bacterial Inhibitor
Cefamandole is a semi-synthetic second-generation cephalosporin antibiotic that functions as a bacterial inhibitor by disrupting cell wall synthesis. It exhibits broad-spectrum antimicrobial activity against various Gram-positive cocci and several Gram-negative bacilli, while maintaining resistance to hydrolysis by certain β-lactamases. Although effective in many contexts, it shows limited efficacy against species such as Pseudomonas, Proteus vulgaris, and Providencia stuartii. Cefamandole is primarily excreted in the urine in its active form and is utilized in research applications focused on bacterial infections, although its penetration across the blood-brain barrier is minimal. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Antibacterial Agent
Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent that inhibits dihydropteroate synthase, thereby blocking folic acid synthesis. Its antibacterial properties make it useful in various applications, including blood kinetic studies and research focused on microbial resistance mechanisms. This compound is valuable for scientists investigating the effects of folate metabolism and the therapeutic potential of sulfonamides. -
Antibiotic
Nitrofurantoin sodium is a potent, orally active antibiotic targeting bacterial infections. It exhibits broad-spectrum antibacterial activity, making it particularly effective against urinary tract infections (UTIs), including cystitis and pyelonephritis. This reagent is valuable for research applications focusing on UTI treatment and mechanisms of bacterial resistance. -
Antibiotic
Oleandomycin phosphate is a macrolide antibiotic that exhibits similar structural characteristics to Erythromycin. It functions by inhibiting protein synthesis, specifically by interfering with the translation of activated amino acids into nascent peptide chains at the ribosomal site. This compound demonstrates significant antimicrobial activity, making it useful in various research applications related to bacterial infections and antibiotic resistance studies. -
Antibiotic
4-Epitetracycline hydrochloride is a reversible epimer of Tetracycline, functioning as an antibiotic with notable antibacterial activity. This compound has applications in microbiological research for studying bacterial resistance and the mechanisms of action of tetracycline antibiotics. Its ability to interconvert with Tetracycline in natural settings enhances its relevance in antibiotic studies. -
Antibiotic
Bacitracin A is an antibiotic that targets gram-positive bacteria by inhibiting bacterial cell wall biosynthesis. It forms a complex with long-chain polyisoprenyl pyrophosphates in the presence of metal ions, facilitating the dephosphorylation of the lipid carrier intermediate Css-bactoprenyl pyrophosphate. This mechanism of action underscores its utility in microbiological research and studies involving bacterial infections.
