Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Gatifloxacin sesquihydrate is a potent fluoroquinolone antibiotic that primarily targets bacterial type II topoisomerases. It exhibits broad-spectrum antibacterial activity, demonstrating significant inhibition of S. aureus topoisomerase IV and E. coli DNA gyrase with IC50 values of 13.8 μg/ml and 0.109 μg/ml, respectively. This compound is particularly useful in research related to bacterial infections and may serve as a therapeutic agent for conditions such as bacterial conjunctivitis. -
Antibacterial Agent
Ticarcillin is a semisynthetic carboxypenicillin with extended-spectrum antibacterial activity, primarily targeting bacterial cell wall synthesis. It is effective against a range of gram-positive cocci, such as streptococci and staphylococci, as well as most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin is relevant for research applications involving lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intra-abdominal infections. -
Antibiotic
Secnidazole hemihydrate is an orally active azole antibiotic that targets bacterial virulence through its amelioration of Serratia marcescens. This compound acts as an analog of acylhomoserine lactones, effectively inhibiting quorum sensing and reducing the pathogenesis of Pseudomonas aeruginosa. Secnidazole hemihydrate demonstrates antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria in vitro. Its versatile applications in research include the study of diseases such as amoebiasis, giardiasis, and bacterial vaginitis. -
Antibiotic
Teixobactin is a potent antibiotic that primarily targets cell wall synthesis in bacteria. It demonstrates significant antibacterial activity against gram-negative bacteria by binding to the conserved motifs of lipid II and lipid III. This mechanism of action makes Teixobactin a valuable reagent for research focused on bacterial resistance and the development of new antibiotic therapies. -
Antibiotic
Sitafloxacin hydrochloride is a potent fluoroquinolone antibiotic that functions by inhibiting bacterial DNA gyrase and topoisomerase IV, ultimately disrupting bacterial replication. It exhibits significant antibacterial activity against a wide spectrum of both gram-positive and gram-negative bacteria, including anaerobic organisms and atypical pathogens. This compound is primarily applied in research related to respiratory and urinary tract infections. -
Antibiotic
Amoxicillin arginine is an antibiotic that effectively inhibits cell wall biosynthesis by targeting polypeptide synthesis, leading to the disruption of bacterial growth. With good oral absorption and a broad spectrum of antimicrobial activity, it is utilized in various research applications related to bacterial infections and resistance mechanisms. This compound serves as an important tool for studying the pharmacological effects of β-lactam antibiotics in both clinical and laboratory settings. -
Antibiotic
Zanamivir (hydrate)(5:1) is a potent inhibitor of influenza viral neuraminidase, exhibiting IC50 values of 0.95 nM for influenza A and 2.7 nM for influenza B. This compound is widely employed in antiviral research to elucidate the mechanisms of viral infection and to develop therapeutic strategies against influenza viruses. Its high inhibitory efficacy makes it a valuable tool for studying the effects of neuraminidase inhibition in both laboratory and clinical settings. -
Antibacterial Agent
Cloxacillin is an orally active antibacterial agent and β-lactamase inhibitor, exhibiting an IC50 of 0.04 µM. It effectively suppresses the inflammatory response induced by Staphylococcus aureus by inhibiting the activation of mitogen-activated protein kinases (MAPKs), nuclear factor kappa B (NF-κB), and proteins associated with the NLRP3 inflammasome. This compound is useful for research applications focused on bacterial infections and inflammatory processes. -
Cephalosporin Antibiotic
Cefotiam is a parenteral cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, making it a valuable reagent for research in microbiology and infectious disease studies. This compound is commonly used in evaluating bacterial susceptibility and understanding the mechanisms of antibiotic resistance. -
Antibiotic
Netilmicin is a broad-spectrum semisynthetic aminoglycoside antibiotic targeting bacterial protein synthesis. It demonstrates significant antibacterial activity against aminoglycoside-susceptible gram-negative strains as well as aminoglycoside-resistant strains, including Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with a minimum inhibitory concentration (MIC) ranging from 0.125 to 8 μg/mL. This compound is widely used in research applications focusing on antimicrobial susceptibility and resistance mechanisms. -
Antibiotic
Cefepime chloride is a broad-spectrum cephalosporin antibiotic that effectively targets both Gram-positive and Gram-negative aerobic bacteria. Its ability to penetrate the blood-brain barrier makes it a valuable agent in the treatment of central nervous system infections. Additionally, it is noted for its neurotoxic effects, making it relevant for studies investigating antimicrobial toxicity and resistance mechanisms. -
Antibacterial Antibiotic
Tebipenem pivoxil hydrochloride is an orally active antibacterial agent that targets penicillin-binding proteins (PBPs) to inhibit cell wall synthesis in pathogenic bacteria. This mechanism of action makes it effective against a broad spectrum of Gram-positive and Gram-negative organisms. It is utilized in research applications focused on antibiotic resistance and the development of novel antibacterial therapies. -
Cephalosporin Antibiotic
Cephalexin hydrochloride monohydrate is a semisynthetic cephalosporin antibiotic that primarily targets penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis. It exhibits a wide antibacterial spectrum, effective against various gram-positive and gram-negative bacteria. This compound is utilized in research related to bacterial infections, including pneumonia, strep throat, and bacterial endocarditis. -
Dianionic Cephem Antibiotic
Ceftibuten monohydrate is a dianionic cephem antibiotic that exhibits potent antibacterial activity. It is effective against a broad spectrum of gram-negative bacteria and select gram-positive strains. Ceftibuten is primarily utilized in research applications focusing on antibiotic resistance and the pharmacological evaluation of cephalosporins. Its oral bioavailability makes it a valuable compound for studying systemic infection models. -
Antibiotic
Sitafloxacin monohydrate is a potent fluoroquinolone antibiotic that exhibits strong antibacterial activity against a wide spectrum of both gram-positive and gram-negative bacteria, including anaerobic organisms and atypical pathogens. Its antichlamydial properties make it a valuable reagent in the study of various infections. Sitafloxacin monohydrate is particularly relevant in research focused on respiratory and urinary tract infections. -
Cephalosporin Antibiotic
Cephalexin (lysine) is a semisynthetic cephalosporin antibiotic that primarily targets penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis. This compound exhibits broad-spectrum antibacterial activity against a range of gram-positive and gram-negative bacteria. Cephalexin (lysine) is used in research applications related to various infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. -
β-lactam Antibiotic
Dicloxacillin is a β-lactam antibiotic belonging to the penicillin family, primarily targeting Gram-positive bacteria. It demonstrates effectiveness against β-lactamase-producing organisms, including Staphylococcus aureus. This compound is widely utilized in research and clinical applications to investigate bacterial resistance mechanisms and evaluate the efficacy of antibacterial treatments. -
Antibiotic
A83016A is a kinamycin-type antibiotic that inhibits bacterial growth by targeting essential cellular processes. It exhibits a minimum inhibitory concentration (MIC) of 4 µg/ml against Enterococcus faecium, demonstrating its potent antibacterial activity. This compound is suitable for research applications focused on antibiotic resistance and efficacy studies in microbiology. -
Antibiotic
Antibiotic SF-2132 is a peptide antibiotic derived from Nocardiopsis sp., demonstrating potent inhibitory activity against β-lactam antibiotic-resistant strains, including Pseudomonas and Escherichia. This compound is particularly valuable in research aimed at addressing antibiotic resistance and investigating novel antimicrobial mechanisms. Its efficacy against resistant pathogens makes it a crucial tool for studies in microbiology and infectious disease. -
Antibiotic
Aurodox is an antibiotic derived from a variant of Streptomyces, primarily targeting gram-positive bacteria. It exhibits potent antibacterial activity while demonstrating low toxicity in murine models. Aurodox is utilized in research applications related to antibiotic efficacy and potential growth promotion in agricultural settings. -
Cephalosporin Antibiotic
Cefetecol is a broad-spectrum cephalosporin antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis, leading to cell lysis. In addition to its antibacterial properties, Cefetecol also acts as an α-glucosidase inhibitor, demonstrating in vivo anti-diabetic activity in diabetic mouse models. This compound is suitable for research applications in both antibacterial and anti-diabetic studies. -
Antibiotic
Anti-MRSA agent 19 is an antibiotic that targets methicillin-resistant Staphylococcus aureus (MRSA), demonstrating significant antimicrobial activity with a median MIC of 4 μg/mL. This compound effectively inhibits a diverse range of bacterial species, including those resistant to vancomycin, aminoglycosides, tetracyclines, and oxazolidinones. It serves as a valuable research tool for studying antibiotic resistance mechanisms and developing novel therapeutic strategies against resistant infections. -
Antibiotic
Antibiotic TAN-592B is a potent antibiotic targeting bacterial infections. It exhibits strong antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, making it suitable for research in bacterial pathogenesis and antibiotic resistance studies. This compound can be utilized in assays to evaluate the effectiveness of antibiotic treatments and to explore novel therapeutic approaches to combat bacterial infections. -
Siderophore-antibiotic Conjugate
Albomycin ε is a siderophore-antibiotic conjugate that primarily targets bacterial ribosomes, exhibiting a minimum inhibitory concentration (MIC) of >512 μg/mL. This compound demonstrates significant antibacterial activity, making it a valuable tool for research focused on Streptococcus pneumoniae and Staphylococcus aureus infections. Its unique mechanism of action offers potential insights into novel therapeutic strategies against resistant bacterial strains. -
Antibiotic
2-Acetyl-2-decarboxamidotetracycline functions as an antibiotic within the tetracycline class, targeting bacterial protein synthesis by inhibiting the 30S ribosomal subunit. This compound displays a UV absorption spectrum similar to that of tetracycline and 5-oxytetracycline, particularly above 300 nm, indicative of its BCD-ring structure. Its biological activity makes it a valuable reagent in microbiological research and antibiotic development studies. -
Antibiotic
KU13 is an antibiotic that acts as an inhibitor of nontuberculous mycobacteria (NTM). It demonstrates potent activity with minimum inhibitory concentrations (MIC) ranging from 0.032 to 8 μg/mL against Mycobacterium and 2 μg/mL against E. coli. This compound is valuable for research focused on anti-infective agents and the development of treatments for mycobacterial infections. -
Antibiotic
PD117588 is a quinolone antibacterial agent targeting a wide spectrum of bacterial infections. It demonstrates potent activity against both Gram-positive and Gram-negative bacteria, notably showing effectiveness against methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococci, and Enterococci. Additionally, PD117588 exhibits considerable efficacy against various Gram-negative bacilli, offering a competitive minimum inhibitory concentration compared to other quinolone antibiotics, including imipenem and ceftazidime. This compound is suitable for research applications in antimicrobial resistance and antibiotic development. -
Antibiotic
TANDEM (Des-N-tetramethyltriostin A) is a synthetic antibiotic that primarily inhibits the proliferation of tumor cells. This compound demonstrates significant anticancer activity across various cancer cell lines in vitro, making it a valuable tool for cancer research. TANDEM can be utilized in combination with chemotherapeutic agents to enhance their inhibitory effects. Its mechanism of action involves disruption of cell proliferation and survival pathways, effectively targeting malignant cells during treatment. -
Antibiotic
L-Azatyrosine is an antitumor antibiotic that targets transformed cells by restoring normal phenotypic behavior in those bearing oncogenic Ras genes. Isolated from the bacterium Streptomyces chibaensis, L-Azatyrosine exhibits significant biological activity in cancer research, making it a valuable tool for studying tumor biology and therapeutic interventions. Its unique properties can assist in elucidating the molecular mechanisms underlying oncogenesis and potential treatment strategies. -
Antibiotic
Kapurimycin A3 is an antibiotic with antitumor and antibacterial properties, primarily targeting DNA. Its mechanism involves DNA binding and inducing strand breakage, making it effective in disrupting cellular processes in both bacterial and cancer cells. This compound is isolated from the naturally occurring bacterium Streptomyces, offering a valuable tool for research in cancer therapeutics and antimicrobial studies. -
Antibacterial/Antimalarial
1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid that exhibits antibacterial and antimalarial properties. This compound is derived from an Indonesian sponge and has potential applications in the study of infectious and tropical parasitic diseases. Its unique structural features may offer insights into the development of new therapeutic strategies against challenging pathogens. -
Antitumor Antibiotic
Sarubicin A is an antitumor antibiotic that exhibits potent activity against various Gram-positive and Gram-negative bacteria. Its primary mechanism involves inhibition of bacterial protein synthesis, contributing to its antimicrobial properties. Additionally, Sarubicin A demonstrates significant antitumor activity, making it a valuable reagent for cancer research and the investigation of antibiotic resistance mechanisms. -
Macrocyclic Antibiotic
Soralimixin is a synthetic macrocyclic peptide antibiotic derived from polymyxins, designed for intravenous administration. This compound exhibits potent antibacterial activity against drug-resistant Gram-negative pathogens, making it a valuable tool for studying difficult-to-treat infections. Soralimixin's unique mechanism of action enhances therapeutic options in the fight against antibiotic-resistant bacterial strains, facilitating various research applications in infectious disease. -
Antibacterial Agents
Cefetamet pivoxyl is a cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of enteropathogens, specifically Gram-negative bacteria, with the exception of Pseudomonas aeruginosa, as well as Legionella pneumophila. This compound is primarily utilized in research related to antibacterial efficacy and the development of new antimicrobial therapies. -
Glycopeptide Antibiotic
Balhimycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the D-alanine-D-alanine termini of precursor units. This compound exhibits potent antibacterial activity against strains of staphylococci and various anaerobic bacteria, making it valuable in the study of antibiotic resistance and infection management. Its application extends to research focused on the mechanisms of antibacterial action and the development of novel therapeutic agents. -
Antibacterial Agent
Carumonam is a sulfonated monocyclic β-lactam antibiotic that specifically targets penicillin-binding proteins (PBPs). It demonstrates potent antibacterial activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while exhibiting limited to no inhibitory effect on Streptococcus pneumoniae and Staphylococcus aureus. Additionally, Carumonam is resistant to beta-lactamase-mediated hydrolysis, making it a valuable compound for research on antibiotic resistance and infection control studies. -
Antibiotic
Miloxacin is an orally active bacteriostatic agent that primarily targets Gram-negative bacteria. It exhibits antibacterial properties that are comparable to those of Oxolinic acid and Nalidixic acid. Miloxacin is utilized in research applications focusing on the mechanisms of antibiotic action and the development of resistance in bacterial populations. -
Antibiotic/Antitumor Agent
Acetomycin is an antibiotic with potent antitumor activity. It effectively inhibits the growth of CT-8 human colon adenocarcinoma cells with an IC50 of 1.5 μg/mL and L1210 murine leukemia cells with an IC50 of 2.2 μg/mL. This compound can be isolated from the actinomycete WP-2661 and is valuable for research in cancer biology and antibiotic studies. -
Antibiotic
AA-57 is an acidic lipophilic antibiotic derived from the fermentation broth of Actinomycetes strain AA-57, isolated from soil samples in Koriyama City, Fukushima Prefecture, Japan. This compound demonstrates potent antibacterial activity against a diverse range of microorganisms, including Gram-positive, Gram-negative, and acid-fast bacteria. AA-57 is utilized in research focused on antibiotic development and microbial resistance, providing a valuable tool for studying bacterial pathogenesis and therapeutic interventions. -
Antibiotic
OCA 983 is an orally active tetrahydrofuranyl 1β-methylcarbapenem antibiotic that primarily targets bacterial cell wall synthesis. It demonstrates potent inhibitory activity against both class A and class C β-lactamases, making it effective against resistant bacterial strains. This compound possesses a broad antibacterial spectrum and is relevant for research applications involving infectious diseases and antibiotic resistance mechanisms. -
Antitumour Antibiotic
Anthramycin is a potent antitumor antibiotic belonging to the pyrolobenzodiazepine (PBD) family. It exhibits significant cytotoxicity against various cancer cell lines, making it valuable for cancer research. Additionally, Anthramycin has been identified as a strong antagonist of cholecystokinin in the central nervous system of murine models, highlighting its potential in neurobiological studies. This compound is essential for investigations into its mechanisms of action in both cancer therapy and neuropharmacology. -
Antibacterial Agent
Pseudomonic acid C is an antibacterial agent that targets bacterial cell wall synthesis through inhibition of isoleucyl-tRNA synthetase. This compound exhibits potent antibacterial activity against various Gram-positive bacteria, making it a valuable tool for research in microbiology and antibiotic development. Its mechanism offers insights into bacterial resistance and the potential for novel therapeutic strategies. -
Antibiotic
Teicoplanin A2-4 is an antibiotic that targets Gram-positive bacteria, exhibiting potent activity against both aerobic and anaerobic strains. It disrupts cell wall synthesis, leading to bacterial cell lysis. This compound is widely used in research related to bacterial infections and in the study of antibiotic resistance mechanisms. -
Antibiotic
Tetracycline 10-O-ß-D-galactopyranoside is an antibiotic that targets bacterial protein synthesis by inhibiting the 30S ribosomal subunit. This compound exhibits broad-spectrum antimicrobial activity, making it effective against a variety of gram-positive and gram-negative bacteria. It is commonly utilized in molecular biology research for gene expression studies and the development of antibiotic resistance models. -
Antibacterial Agent
Pipemidic acid trihydrate is an antibacterial agent that targets DNA gyrase to exert its effects. This compound demonstrates activity against a range of gram-negative bacteria, including Pseudomonas aeruginosa, as well as certain gram-positive bacteria. It is suitable for research focused on intestinal, urinary, and biliary tract infections, providing a valuable tool for studying bacterial resistance and therapeutic interventions. -
Fluoroquinolone Antibiotic
DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies. -
Fluoroquinolone Antibiotic
Tosufloxacin hydrochloride is a fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. This compound is utilized in research applications involving the study of bacterial infections and the development of antibiotic resistance mechanisms. -
Antibiotic
Kazusamycin B is an antibiotic derived from the fermentation broth of Streptomyces sp. No. 81-484. It is known to inhibit cell proliferation and effectively arrests the cell cycle at the G1 phase. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Antibiotic
CB-182804 is a polypeptide antibiotic targeting Gram-negative pathogenic bacteria. It exhibits potent inhibitory activity against a range of pathogens, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa, with MIC50 values of 2 μg/mL. This compound is primarily utilized in research focused on refractory infections caused by multidrug-resistant Gram-negative bacteria, providing a valuable tool in the study of antimicrobial resistance and treatment strategies. -
Antibiotic
Zelkovamycin is a cyclic peptide antibiotic that targets bacterial cell growth. It demonstrates potent antimicrobial activity against a range of pathogens, including Xanthomonas oryzae, Pyricularia oryzae, Staphylococcus aureus, and Achromobacter laidlawii, with inhibitory effects observed at concentrations from 0.01 to 300 μg/mL. This compound is valuable for research applications focused on antibiotic resistance and bacterial pathogenesis.
