I-XW-053 is a specific inhibitor of the HIV-1 capsid protein, demonstrating antiviral activity by disrupting the interaction at the N-terminal domain interface (NTD-NTD) of the capsid protein. It effectively suppresses the replication of HIV-189BZ167 with an IC50 value of 164.2 μM. This compound serves as a valuable tool for researchers investigating HIV-1 pathogenesis and potential therapeutic approaches targeting viral replication.
I-XW-053 is a specific inhibitor of the HIV-1 capsid protein, demonstrating antiviral activity by disrupting the interaction at the N-terminal domain interface (NTD-NTD) of the capsid protein. It effectively suppresses the replication of HIV-189BZ167 with an IC50 value of 164.2 μM. This compound serves as a valuable tool for researchers investigating HIV-1 pathogenesis and potential therapeutic approaches targeting viral replication.
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