Catalog No.
Product Name
Application
Product Information
Citations
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Anticancer/Anti-inflammatory/Antibacterial Agent
Aspergillumarin A is a dihydroisocoumarin derivative that primarily targets antitumor and anti-inflammatory pathways. It inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 hepatocellular carcinoma cells, making it a valuable tool for cancer research, particularly in studies of hepatocellular carcinoma (HCC). Additionally, Aspergillumarin A demonstrates weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis, supporting its potential use in exploring antibacterial applications. -
Bacterial Biofilm Inhibitor
Antibacterial synergist 1 (compound 20P) is an effective bacterial biofilm inhibitor. It specifically inhibits the production of pyocyanin and biofilm formation in Pseudomonas aeruginosa with IC50 values of 8.6 μM and 4.5 μM, respectively. This compound is valuable for researching therapeutic strategies against P. aeruginosa infections, particularly in the context of chronic infections characterized by biofilm development. -
Antibacterial Agent
Cucurbitacin F is a bioactive compound extracted from Hemsleya gigantha, primarily acting as an antibacterial agent. It exhibits significant antibacterial properties, making it a valuable tool for studies focused on bacterial infections. This reagent can aid in the exploration of antimicrobial mechanisms and the development of new therapeutic approaches in combating bacterial pathogens. -
Bacterial Inhibitor
Eupatarone, also known as Caleprunin B, is a bacterial inhibitor derived from Calea platylepis. This compound exhibits significant antibacterial activity, making it a valuable tool in research focused on combating bacterial infections. Its ability to inhibit bacterial growth positions Eupatarone as an important reagent in microbiological studies and drug discovery efforts targeting antibiotic resistance. -
Antibacterial Agent
Antibacterial agent 106 is a potent antibacterial compound targeting multi-drug resistant Gram-positive pathogens. This orally active agent demonstrates significant antibacterial efficacy, achieving a 99.7% clearance of intracellular methicillin-resistant Staphylococcus aureus (MRSA) within macrophages. Additionally, antibacterial agent 106 features an alkyne moiety, facilitating its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, offering valuable applications in chemical biology and medicinal research. -
Bacterial Inhibitor
Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide derived from Bombina species, primarily functioning as a bacterial inhibitor. This peptide exhibits potent activity against a range of bacterial strains, making it a valuable tool for research in antimicrobial resistance and the development of new therapeutic agents. Its unique mechanism and efficacy position it as an important candidate for studies focused on infection control and peptide-based drug design. -
Antibacterial Agent
α-Mycolic acid (C80) is a structural lipid of the mycobacterial cell wall, primarily targeting membrane integrity. Isolated from Mycobacterium tuberculosis Canetti, this compound plays a crucial role in modulating membrane permeability and stability. It is valuable for research applications focused on understanding and treating infections caused by Mycobacterium tuberculosis. -
Antibacterial Agent
Antibacterial Agent 44 is a potent antibacterial compound designed to target bacterial pathogens. This agent exhibits significant antibacterial activity, making it suitable for investigating various bacterial infections. Its efficacy in research supports the development of novel therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 103 primarily targets bacterial cells, exhibiting strong antibacterial activity against a wide range of both Gram-positive and Gram-negative bacteria. This reagent is valuable for research involving the inhibition of resistant bacterial strains, making it a critical tool for studies aimed at addressing antibiotic resistance in clinical settings. -
Antibacterial Agent
Antibacterial Agent 79 is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research into antibiotic mechanisms and resistance. This agent is suitable for studies focused on understanding bacterial infections and developing new therapeutic strategies. -
Antibacterial Agent
Rupesin E is a natural antibacterial agent derived from Patrinia rupestris, exhibiting potent activity against Escherichia coli. This compound is valuable for research into antimicrobial strategies and the development of novel antibacterial therapies. Its efficacy in targeting bacterial infections highlights its potential applications in pharmaceutical research and infection control studies. -
Antibacterial Agent
U-97456 is an N-hydroxyacetyl derivative with potent antibacterial properties, specifically targeting Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of less than 50 μg/mL against the M. tuberculosis H37Rv strain. This compound is useful for research focused on infectious diseases, particularly in the development of novel antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 98 (Compound G37) is a potent orally active antibacterial compound that primarily targets Gyrase B by inhibiting its ATPase activity. This mechanism disrupts DNA supercoiling in Staphylococcus aureus, effectively exhibiting antibacterial activity. Notably, Antibacterial Agent 98 does not promote the development of resistance in methicillin-resistant S. aureus (MRSA), making it a valuable candidate for research in antimicrobial resistance. -
Anticandidal Agent
Anticandidal agent-1 is a potent broad-spectrum agent targeting Candida species, exhibiting significant anticandidal activity against Candida albicans and Candida glabrata, with MIC50 values of 8.65 and 13.51 μg/mL, respectively. This compound effectively inhibits biofilm formation by disrupting hyphal elongation and filamentation, making it a valuable tool for studying candidiasis and developing antifungal treatments. Its mechanism of action positions it as a crucial reagent for research in fungal pathogenesis and infection control. -
Bacterial Inhibitor
Antimicrobial agent-21 is a potent bacterial inhibitor that demonstrates significant activity against both gram-positive and gram-negative bacteria. This compound serves as a valuable tool in microbiological research and antibiotic development, aiding in the study of bacterial resistance mechanisms and the efficacy of new antimicrobial strategies. Its broad-spectrum activity makes it applicable in various experimental settings focused on understanding bacterial pathogenesis and treatment. -
Bacterial
MBX-1162 is a bisindole compound that primarily targets bacterial resistance mechanisms. This compound has been studied in relation to Staphylococcus aureus, demonstrating a unique resistance profile without cross-resistance to similar compounds. Research indicates that MBX-1162's activity is associated with the substrate specificity of the MepA and MepR proteins, making it a valuable tool for investigating bacterial resistance and developing novel therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 61 is a potent antibacterial compound targeting specific bacterial pathways. Its primary mechanism involves disruption of bacterial cell wall synthesis, leading to cell lysis and death. This reagent is essential for research applications focused on antibiotic resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
Carbendazim mixture with flusilazole is a potent bacterial inhibitor utilized in the management of sooty mold, particularly attributable to Botrytis narcissicola. This fungicide combination demonstrates efficacy in diminishing lesion size and alleviating secondary sooty mold symptoms, especially when employed alongside other fungicides. In field trials conducted in regions such as Cambridgeshire and Lincolnshire, the application of this mixture significantly controlled sooty mold and enhanced bulb production by employing a strategic spray program that alternated fungicides with varying modes of action. This research emphasizes the importance of selecting appropriate fungicides and methodologies to optimize disease management while minimizing the required applications. -
Antibacterial Agent
Angustifoline hydrochloride is an alkaloid derived from the extract of Lupinus angustifolius L. This compound demonstrates significant antibacterial properties, exhibiting bacteriostatic effects against a range of organisms, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Bacillus thuringiensis. Its antimicrobial activity makes it an important reagent for research in the field of antibacterial drug development and microbiology. -
Antibacterial Agent
Antibacterial Agent 154 is a derivative of fluoroquinolones designed to target bacterial strains effectively. It exhibits robust antibacterial activity against both Gram-positive and Gram-negative bacteria. In preclinical studies, Antibacterial Agent 154 displayed significant in vivo efficacy in a mouse model of staphylococcal sepsis, highlighting its potential for further research in antibacterial therapies. -
Antibacterial Agent
Cerastecin D is an antibacterial agent with activity against Acinetobacter baumannii ATCC19606, exhibiting an MITC95 value of 165 nM. This compound is valuable in research focused on bacterial resistance and development of new antimicrobial therapies. Its potential for targeting multi-drug resistant pathogens makes it significant in the field of infectious disease research. -
Antibiotic
Respinomycin A1 is a natural antibiotic derived from Streptomyces sp. RK-483, exhibiting antimicrobial activity against various bacterial strains. This compound has been shown to induce differentiation in leukemic K-562 cells, highlighting its potential utility in cancer research and therapeutic development. Its unique mechanism of action makes Respinomycin A1 a valuable tool for investigating cellular differentiation and the pathways involved in leukemia. -
Bacterial Inhibitor
Cellocidin is a bacterial inhibitor that targets the α-ketoglutarate-succinate system in Xanthomonas species. This agricultural antibiotic demonstrates preventive activity against rice bacterial leaf blight, offering a valuable tool for managing bacterial infections in crop production. Its mechanism of action makes it an essential reagent for research into plant-pathogen interactions and the development of sustainable agricultural practices. -
Bacterial Inhibitor
Phentolamine acetate is a bacterial inhibitor that targets and disrupts the growth of specific bacterial strains, including Staphylococcus aureus. This compound exhibits notable anti-inflammatory and anticancer properties, highlighting its potential for diverse biological applications. Its significant in vitro activity makes it a valuable tool for researchers studying bacterial infections and inflammation-related disorders. -
Antibacterial Agent
Sulfamethomidine is a sulfonamide antibiotic that primarily targets bacterial folic acid synthesis by inhibiting dihydropteroate synthase. This compound exhibits potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria. It is commonly utilized in research applications focusing on antimicrobial efficacy, resistance mechanisms, and the development of combination therapies. -
Antibacterial Agent
7-Phloroeckol is a potent antibacterial agent targeting virulence-associated proteins of Pseudomonas aeruginosa. It demonstrates strong and stable binding to 18 distinct proteins, highlighting its potential in combating bacterial infections. This compound is valuable for research focused on understanding and treating Pseudomonas aeruginosa infections. -
Antibacterial agent
Antibacterial agent 160 is a potent antibacterial compound that disrupts bacterial DNA function, leading to cell death. This reagent effectively eliminates bacterial cells and inhibits biofilm formation, making it a valuable tool for studies on bacterial infections and resistance mechanisms. Its application extends to researching antibacterial efficacy and strategies for combating biofilm-associated infections. -
Antibacterial Agent
Javanicin is an antibacterial agent that targets various pathogenic bacteria, demonstrating activity against Bacillus megaterium, Staphylococcus aureus, Salmonella typhi, and Escherichia coli. Additionally, Javanicin exhibits weak cytotoxicity against the human lung cancer cell line, making it a potential candidate for research into antibacterial and anticancer applications. -
Antibacterial Agent
Antibacterial agent 156 is a potent bactericidal compound that selectively targets cell-wall synthesis in Clostridium difficile. This agent demonstrates significant antibacterial activity, with a minimal inhibitory concentration (MIC) of 0.5 μg/mL against a broad range of strains (MIMIC50 of 101 strains) and an MIC90 of 1 μg/mL. It is an important tool for research applications focused on combating C. difficile infections and studying bacterial cell-wall biosynthesis. -
Antibacterial Agent
Antibacterial Agent 255 is a selective inhibitor of 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE), demonstrating potent antibacterial activity with IC50 values of 13.0 µM for E. coli IspE, 8.0 µM for K. pneumoniae IspE, and 20 µM for A. baumannii IspE. This compound is instrumental in the study of bacterial biosynthesis pathways and can be utilized in antibacterial drug development research. -
Bacterial Inhibitor
Ethionamide hydrochloride is an antituberculosis agent that acts as a bacterial inhibitor. It disrupts mycobacterial cell wall synthesis by inhibiting fatty acid synthesis, leading to potential bacteriostatic or bactericidal effects based on concentration and microorganism susceptibility. Ethionamide hydrochloride forms an adduct with NAD+, which is crucial for its antimicrobial activity. This compound is primarily utilized in research for understanding tuberculosis treatment and the mechanisms of drug resistance in Mycobacterium tuberculosis. -
Antibacterial Agent
5-Hydroxymethyl flucloxacillin is an active metabolite of Flucloxacillin, targeting bacterial infections. This compound demonstrates notable antibacterial activity, making it useful for research applications focused on antimicrobial resistance and bacterial pathogenesis studies. Its efficacy in inhibiting bacterial growth supports investigations into therapeutic strategies for treating infections caused by resistant strains. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Anti-Bacterial Agent
Saquayamycin C is an anti-bacterial agent with significant antimicrobial activity, though it exhibits a weaker efficacy against Gram-negative bacteria. This compound also demonstrates cytotoxic effects against leukemia P388 cells, including those resistant to Adriamycin. Its applications extend to research in cancer biology and microbial resistance, making it valuable for studies focused on therapeutic development and resistance mechanisms. -
Antibacterial
NR-NO2 is an innovative antibacterial agent that acts by producing reactive nitrogen species, thereby disrupting bacterial cell function. Its bioactivity involves the inhibition of bacterial growth, making it suitable for research applications in the development of new antibacterial therapies. Additionally, NR-NO2 offers potential in imaging-based guidance due to its unique targeting capabilities, enhancing its use in both antitumor and antibacterial research contexts. -
Antibacterial/anticancer Agent
1-Hydroxy-3,5-dimethoxyxanthone, a xanthone derivative, serves as an effective antibacterial and anticancer agent. Isolated from Lomatogonium rotatum, this compound demonstrates inhibitory effects on the growth of Pseudomonas aeruginosa and Escherichia coli, achieving a minimum inhibitory concentration (MIC) of 640 μg/mL. Additionally, 1-Hydroxy-3,5-dimethoxyxanthone shows significant anticancer activity against various cancer types, including cervical, breast, melanoma, liver, and gastric cancers, making it a valuable tool for biological research and therapeutic development. -
Lipopeptide Antibiotic
Friulimicin D is a lipopeptide antibiotic derived from the actinomycete Actinoplanes friuliensis. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria. Research applications include the study of bacterial resistance mechanisms and the potential development of novel antimicrobial therapies. -
Antibacterial Agent
4-Ethyloctane is a potent antibacterial agent targeting bacterial infections. Demonstrating strong activity against Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 0.04 mg/mL, it serves as a valuable compound for the study of antibacterial properties and mechanisms. Researchers can utilize 4-Ethyloctane in investigations aimed at understanding bacterial resistance and the development of potential therapeutic applications. -
Antibacterial Agent
8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid that functions as an antibacterial agent. It demonstrates significant activity against various bacterial strains, including Staphylococcus aureus, Shigella flexneri, and Salmonella paratyphi-B, with minimal inhibitory concentration (MIC) values of 6.25 μg/mL. This compound is valuable for research in antimicrobial efficacy and the development of new antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 108 is a potent antibacterial compound targeting bacterial pathogens. It exhibits a minimum inhibitory concentration (MIC) of 3 μM against methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant strains. This compound is suitable for research applications in studying bacterial infections and developing new antibacterial therapies. -
Antibacterial Agent
Altromycin A is a natural antibacterial agent classified as a Pluramycin analog. It demonstrates significant activity against a range of bacterial strains, making it a valuable tool for studying bacterial infections and developing new antimicrobial strategies. Its mechanism of action involves interference with protein synthesis, which is critical for bacterial growth and survival. Research applications include antibiotic susceptibility testing and the investigation of resistance mechanisms. -
Antibacterial Agent
YXL-13 is a potent inhibitor of Pseudomonas aeruginosa (PAO1) with an IC50 value of 3.686 μM. This compound effectively targets the quorum sensing (QS) system, leading to inhibition of virulence factors and biofilm formation, thereby reducing both pathogenicity and antibiotic resistance. YXL-13 is suitable for research applications focused on the development of antibacterial strategies against PAO1 infections. -
Antibacterial Agent
11-Keto fusidic acid is an antibacterial agent that demonstrates potent activity against Staphylococcus aureus, exhibiting a minimal inhibitory concentration (MIC) of 0.078 μg/mL. Its effectiveness makes it a valuable compound for research focused on microbial infections and the development of novel antibacterial therapies. This compound can aid in the exploration of resistance mechanisms and therapeutic strategies in bacterial pathogenesis. -
antibacterial
Emeguisin A is a depsidone that exhibits notable antibacterial activity. It has been shown to inhibit cell viability in human colon carcinoma (HCT-116) cells by approximately 87.06%. This compound is valuable for research applications focused on developing antibacterial agents and studying the effects of natural products on cancer cell lines. -
Anti-Bacterial Agent
Saframycin F is an anti-bacterial agent primarily targeting Gram-positive bacteria. It demonstrates potent inhibitory activity against mouse lymphocyte L-1210, with an ID50 of 0.59 μM. This compound is useful in research applications focused on antibacterial activity and immune response modulation. -
Antibacterial Agent
Antibacterial Agent 321 is a lipophilic compound that targets bacterial cell membranes, inducing structural disruption. This agent exhibits phototoxic effects against both Staphylococcus aureus and Escherichia coli, demonstrating significant antibacterial activity. Antibacterial Agent 321 is suitable for research applications focusing on bacterial infection mechanisms and therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 198 is a potent antibacterial compound targeting gram-positive bacteria, specifically Staphylococcus aureus and various Enterococcus strains. This reagent exhibits significant antibacterial activity, making it a valuable tool for research focused on bacterial resistance and infection control mechanisms. Its application in microbiological studies provides insights into the efficacy of antibacterial agents and contributes to the development of new therapeutic strategies. -
Asperlicin
Asperlicin D is an metabolite derived from the Aspergillus alliaceus strain (ATCC 20656), primarily involved in the regulation of fungal biosynthesis. It exhibits antifungal and antibacterial activities through inhibition of various biological pathways. Due to its potential therapeutic properties, Asperlicin D is of interest in studies related to natural product chemistry and antimicrobial drug development. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications.
