Catalog No.
Product Name
Application
Product Information
Citations
-
Antibacterial Agent
α-Mycolic acid (C80) is a structural lipid of the mycobacterial cell wall, primarily targeting membrane integrity. Isolated from Mycobacterium tuberculosis Canetti, this compound plays a crucial role in modulating membrane permeability and stability. It is valuable for research applications focused on understanding and treating infections caused by Mycobacterium tuberculosis. -
Antibacterial Agent
Antibacterial Agent 44 is a potent antibacterial compound designed to target bacterial pathogens. This agent exhibits significant antibacterial activity, making it suitable for investigating various bacterial infections. Its efficacy in research supports the development of novel therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 103 primarily targets bacterial cells, exhibiting strong antibacterial activity against a wide range of both Gram-positive and Gram-negative bacteria. This reagent is valuable for research involving the inhibition of resistant bacterial strains, making it a critical tool for studies aimed at addressing antibiotic resistance in clinical settings. -
Antibacterial Agent
Antibacterial Agent 79 is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research into antibiotic mechanisms and resistance. This agent is suitable for studies focused on understanding bacterial infections and developing new therapeutic strategies. -
Antibacterial Agent
Rupesin E is a natural antibacterial agent derived from Patrinia rupestris, exhibiting potent activity against Escherichia coli. This compound is valuable for research into antimicrobial strategies and the development of novel antibacterial therapies. Its efficacy in targeting bacterial infections highlights its potential applications in pharmaceutical research and infection control studies. -
Antibacterial Agent
U-97456 is an N-hydroxyacetyl derivative with potent antibacterial properties, specifically targeting Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of less than 50 μg/mL against the M. tuberculosis H37Rv strain. This compound is useful for research focused on infectious diseases, particularly in the development of novel antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 98 (Compound G37) is a potent orally active antibacterial compound that primarily targets Gyrase B by inhibiting its ATPase activity. This mechanism disrupts DNA supercoiling in Staphylococcus aureus, effectively exhibiting antibacterial activity. Notably, Antibacterial Agent 98 does not promote the development of resistance in methicillin-resistant S. aureus (MRSA), making it a valuable candidate for research in antimicrobial resistance. -
Anticandidal Agent
Anticandidal agent-1 is a potent broad-spectrum agent targeting Candida species, exhibiting significant anticandidal activity against Candida albicans and Candida glabrata, with MIC50 values of 8.65 and 13.51 μg/mL, respectively. This compound effectively inhibits biofilm formation by disrupting hyphal elongation and filamentation, making it a valuable tool for studying candidiasis and developing antifungal treatments. Its mechanism of action positions it as a crucial reagent for research in fungal pathogenesis and infection control. -
Bacterial Inhibitor
Antimicrobial agent-21 is a potent bacterial inhibitor that demonstrates significant activity against both gram-positive and gram-negative bacteria. This compound serves as a valuable tool in microbiological research and antibiotic development, aiding in the study of bacterial resistance mechanisms and the efficacy of new antimicrobial strategies. Its broad-spectrum activity makes it applicable in various experimental settings focused on understanding bacterial pathogenesis and treatment. -
Bacterial
MBX-1162 is a bisindole compound that primarily targets bacterial resistance mechanisms. This compound has been studied in relation to Staphylococcus aureus, demonstrating a unique resistance profile without cross-resistance to similar compounds. Research indicates that MBX-1162's activity is associated with the substrate specificity of the MepA and MepR proteins, making it a valuable tool for investigating bacterial resistance and developing novel therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 61 is a potent antibacterial compound targeting specific bacterial pathways. Its primary mechanism involves disruption of bacterial cell wall synthesis, leading to cell lysis and death. This reagent is essential for research applications focused on antibiotic resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
Carbendazim mixture with flusilazole is a potent bacterial inhibitor utilized in the management of sooty mold, particularly attributable to Botrytis narcissicola. This fungicide combination demonstrates efficacy in diminishing lesion size and alleviating secondary sooty mold symptoms, especially when employed alongside other fungicides. In field trials conducted in regions such as Cambridgeshire and Lincolnshire, the application of this mixture significantly controlled sooty mold and enhanced bulb production by employing a strategic spray program that alternated fungicides with varying modes of action. This research emphasizes the importance of selecting appropriate fungicides and methodologies to optimize disease management while minimizing the required applications. -
Antibacterial Agent
Angustifoline hydrochloride is an alkaloid derived from the extract of Lupinus angustifolius L. This compound demonstrates significant antibacterial properties, exhibiting bacteriostatic effects against a range of organisms, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Bacillus thuringiensis. Its antimicrobial activity makes it an important reagent for research in the field of antibacterial drug development and microbiology. -
Antibacterial Agent
Antibacterial Agent 154 is a derivative of fluoroquinolones designed to target bacterial strains effectively. It exhibits robust antibacterial activity against both Gram-positive and Gram-negative bacteria. In preclinical studies, Antibacterial Agent 154 displayed significant in vivo efficacy in a mouse model of staphylococcal sepsis, highlighting its potential for further research in antibacterial therapies. -
Antibacterial Agent
Cerastecin D is an antibacterial agent with activity against Acinetobacter baumannii ATCC19606, exhibiting an MITC95 value of 165 nM. This compound is valuable in research focused on bacterial resistance and development of new antimicrobial therapies. Its potential for targeting multi-drug resistant pathogens makes it significant in the field of infectious disease research. -
Antibiotic
Respinomycin A1 is a natural antibiotic derived from Streptomyces sp. RK-483, exhibiting antimicrobial activity against various bacterial strains. This compound has been shown to induce differentiation in leukemic K-562 cells, highlighting its potential utility in cancer research and therapeutic development. Its unique mechanism of action makes Respinomycin A1 a valuable tool for investigating cellular differentiation and the pathways involved in leukemia. -
Bacterial Inhibitor
Cellocidin is a bacterial inhibitor that targets the α-ketoglutarate-succinate system in Xanthomonas species. This agricultural antibiotic demonstrates preventive activity against rice bacterial leaf blight, offering a valuable tool for managing bacterial infections in crop production. Its mechanism of action makes it an essential reagent for research into plant-pathogen interactions and the development of sustainable agricultural practices. -
Bacterial Inhibitor
Phentolamine acetate is a bacterial inhibitor that targets and disrupts the growth of specific bacterial strains, including Staphylococcus aureus. This compound exhibits notable anti-inflammatory and anticancer properties, highlighting its potential for diverse biological applications. Its significant in vitro activity makes it a valuable tool for researchers studying bacterial infections and inflammation-related disorders. -
Antibacterial Agent
Sulfamethomidine is a sulfonamide antibiotic that primarily targets bacterial folic acid synthesis by inhibiting dihydropteroate synthase. This compound exhibits potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria. It is commonly utilized in research applications focusing on antimicrobial efficacy, resistance mechanisms, and the development of combination therapies. -
Antibacterial Agent
7-Phloroeckol is a potent antibacterial agent targeting virulence-associated proteins of Pseudomonas aeruginosa. It demonstrates strong and stable binding to 18 distinct proteins, highlighting its potential in combating bacterial infections. This compound is valuable for research focused on understanding and treating Pseudomonas aeruginosa infections. -
Antibacterial agent
Antibacterial agent 160 is a potent antibacterial compound that disrupts bacterial DNA function, leading to cell death. This reagent effectively eliminates bacterial cells and inhibits biofilm formation, making it a valuable tool for studies on bacterial infections and resistance mechanisms. Its application extends to researching antibacterial efficacy and strategies for combating biofilm-associated infections. -
Antibacterial Agent
Javanicin is an antibacterial agent that targets various pathogenic bacteria, demonstrating activity against Bacillus megaterium, Staphylococcus aureus, Salmonella typhi, and Escherichia coli. Additionally, Javanicin exhibits weak cytotoxicity against the human lung cancer cell line, making it a potential candidate for research into antibacterial and anticancer applications. -
Antibacterial Agent
Antibacterial agent 156 is a potent bactericidal compound that selectively targets cell-wall synthesis in Clostridium difficile. This agent demonstrates significant antibacterial activity, with a minimal inhibitory concentration (MIC) of 0.5 μg/mL against a broad range of strains (MIMIC50 of 101 strains) and an MIC90 of 1 μg/mL. It is an important tool for research applications focused on combating C. difficile infections and studying bacterial cell-wall biosynthesis. -
Antibacterial Agent
Antibacterial Agent 255 is a selective inhibitor of 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE), demonstrating potent antibacterial activity with IC50 values of 13.0 µM for E. coli IspE, 8.0 µM for K. pneumoniae IspE, and 20 µM for A. baumannii IspE. This compound is instrumental in the study of bacterial biosynthesis pathways and can be utilized in antibacterial drug development research. -
Bacterial Inhibitor
Ethionamide hydrochloride is an antituberculosis agent that acts as a bacterial inhibitor. It disrupts mycobacterial cell wall synthesis by inhibiting fatty acid synthesis, leading to potential bacteriostatic or bactericidal effects based on concentration and microorganism susceptibility. Ethionamide hydrochloride forms an adduct with NAD+, which is crucial for its antimicrobial activity. This compound is primarily utilized in research for understanding tuberculosis treatment and the mechanisms of drug resistance in Mycobacterium tuberculosis. -
Antibacterial Agent
5-Hydroxymethyl flucloxacillin is an active metabolite of Flucloxacillin, targeting bacterial infections. This compound demonstrates notable antibacterial activity, making it useful for research applications focused on antimicrobial resistance and bacterial pathogenesis studies. Its efficacy in inhibiting bacterial growth supports investigations into therapeutic strategies for treating infections caused by resistant strains. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Anti-Bacterial Agent
Saquayamycin C is an anti-bacterial agent with significant antimicrobial activity, though it exhibits a weaker efficacy against Gram-negative bacteria. This compound also demonstrates cytotoxic effects against leukemia P388 cells, including those resistant to Adriamycin. Its applications extend to research in cancer biology and microbial resistance, making it valuable for studies focused on therapeutic development and resistance mechanisms. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications. -
Antibacterial Agent
8-Desmethyleleutherin is an antibacterial agent derived from the bulbs of Eleutherine americana. It exhibits potent antibacterial activity with minimal inhibitory concentration (MIC) values of 62.5 µg/mL against Staphylococcus aureus strains ATCC27664 and ATCC25923. This compound is valuable for research applications focusing on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 80 is an antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant inhibitory activity against a wide range of gram-positive and gram-negative bacteria. This reagent is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Antibacterial Agent
Xanthoascin is a natural phenolic metabolite that exhibits strong antibacterial activity. Derived from the fermentation products of the endophytic fungus Aspergillus sp. IFB-YXS found in Ginkgo biloba leaves, Xanthoascin demonstrates a minimum inhibitory concentration (MIC) of 0.3125 µg/mL against Clavibacter michiganense subsp. sepedonicus, along with moderate activity against other bacterial pathogens (MIC = 5-20 µg/mL). Its mechanism involves disrupting bacterial cell membrane permeability, resulting in the leakage of nucleic acids. This compound holds potential for research applications in antimicrobial development and the study of plant pathogen interactions. -
Antibacterial Agent
Penamecillin is an acetoxymethyl ester of Penicillin G designed as an orally active antibacterial agent. It acts by inhibiting bacterial cell wall synthesis, rendering it effective against a range of gram-positive bacteria. This compound is primarily utilized in research applications focused on understanding bacterial resistance and the pharmacodynamics of antibiotic treatments. -
Antibacterial Agent
Anti-MRSA agent 8 is a DAPG derivative that exhibits potent antibacterial activity. This compound targets bacterial cell membranes, disrupting their integrity and function. It is particularly valuable for research focused on methicillin-resistant Staphylococcus aureus (MRSA), making it an essential tool for studies on antibiotic resistance and bacterial infection. -
Antibacterial Agent
Antibacterial Agent 57 is an antibacterial compound that exhibits potent activity against a variety of bacterial strains. Its primary mechanism involves the inhibition of bacterial growth, making it a valuable tool for research applications focused on antimicrobial resistance and the development of new therapeutic agents. This compound is essential for studies investigating the efficacy of novel antibacterial therapies and understanding bacterial pathogenesis. -
Bacterial Inhibitor
Levonadifloxacin arginine is a potent bacterial inhibitor targeting both methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA). This broad-spectrum antistaphylococcal agent exhibits significant antimicrobial activity and has been shown to reduce the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells. Its applications in research include studies focused on bacterial resistance mechanisms and potential therapeutic interventions for staphylococcal infections. -
Antibacterial Agent
WU-FA-01 is a hydrogenated derivative of WU-FA-00, functioning primarily as an antibacterial agent. It demonstrates potent antibacterial activity against Gram-positive bacterial strains, making it a valuable compound for research into antimicrobial therapies. Additionally, WU-FA-01 exhibits some anti-inflammatory properties, suggesting potential applications in studies focused on the interplay between bacterial infections and inflammation. -
Antibacterial Agent
Isomagnolol is a lignan known for its antibacterial properties. Isolated from the roots of the tea plant, it exhibits significant antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections. This compound can be utilized in studies investigating the mechanisms of action behind antibacterial agents and in the development of novel therapeutic strategies. -
Bacterial Inhibitor
Antibacterial Agent 53 is a potent bacterial inhibitor that targets specific bacterial pathways to disrupt cell function. Demonstrating significant antibacterial activity, this compound is primarily utilized in research focusing on the development of novel antimicrobial agents and therapeutic strategies against bacterial infections. Its effectiveness makes it a valuable reagent for studies aimed at understanding bacterial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 109 is an effective antibacterial compound that targets protein synthesis by inhibiting the elongation of peptide chains. It demonstrates strong activity against both gram-positive and gram-negative bacteria while exhibiting non-mutagenic properties. This compound is suitable for research applications focused on bacterial resistance and the mechanisms of antibiotic action. -
Bacterial Inhibitor
Anti Gram-Positive/Negative Bacteria Agent 1 is a bacterial inhibitor that functions through the mechanism of an antibiotic conjugate linked to an artificial MECAM-based siderophore. This compound exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria. It is suitable for research applications aimed at studying bacterial infections and developing new antimicrobial strategies. -
Antibacterial Agent
Antibacterial Agent 117 is a triazole derivative that functions as an effective antibacterial agent targeting MetAP1 in Rickettsia prowazekii, exhibiting an IC50 value of 15 μM. This compound demonstrates the ability to inhibit rickettsial growth, making it valuable for research focused on infectious diseases. Its potential applications include investigating mechanisms of bacterial resistance and developing therapeutic strategies against rickettsial infections. -
Antibacterial Agent
ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies. -
Bacterial Inhibitor
Antitubercular agent-9 is a bacterial inhibitor that demonstrates effective antitubercular activity, with a minimum inhibitory concentration (MIC) ranging from 1.03 to 2.32 μM. This compound is suitable for research focused on tuberculosis treatment mechanisms and the development of new antitubercular therapies. It serves as a valuable tool for understanding bacterial resistance and evaluating potential drug candidates in infectious disease research. -
Antibacterial Agent
Antibacterial Agent 143 (Compound 5a) is a synthetic antibacterial agent that demonstrates effective antimicrobial activity with minimum inhibitory concentrations (MICs) of 25 μg/mL against Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 6538, and 50 μg/mL against Pseudomonas aeruginosa ATCC 13525 and Escherichia coli ATCC 35218. Its potency against a range of Gram-positive and Gram-negative bacteria makes it a valuable tool in antibacterial research and the development of novel therapeutic strategies. This compound is suitable for studies focusing on bacterial resistance mechanisms and the evaluation of new antibacterial formulations. -
Bacterial Inhibitor
Antibacterial Agent 62 is a novel redox cycling compound that targets bacterial cells, demonstrating potent bactericidal activity against both growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria. This reagent is particularly useful in research applications focused on tuberculosis and the development of new antibacterial therapies. Its unique mechanism of action may also aid in understanding resistance mechanisms in various bacterial strains. -
Antibacterial Agent
D-K6L9 is an antibacterial agent that exhibits significant antimicrobial and antibiofilm activities against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. This compound demonstrates stability and resistance to degradation by proteases found in cystic fibrosis sputum, which contributes to its effective performance. Importantly, D-K6L9 does not promote bacterial resistance, making it a valuable tool for research in infectious diseases associated with cystic fibrosis. -
Antibacterial Agent
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] is a cyclic peptide exhibiting potent antibacterial properties, effective against both drug-resistant Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MICs) of 3.1 µg/mL against MRSA (ATCC BAA-1556) and S. aureus (ATCC 29213), and 12.5 µg/mL and 25 µg/mL against P. aeruginosa (ATCC 27883) and E. coli (ATCC 25922), respectively. This compound serves as a crucial tool for researchers exploring novel antibacterial strategies and understanding resistance mechanisms in pathogenic bacteria. -
Antibacterial Agent
Antibacterial Agent 46 is a potent antibacterial agent, specifically developed for targeting bacterial infections. It demonstrates significant inhibitory activity against a range of pathogenic bacteria, making it a valuable tool for research in the field of microbiology. This compound can be utilized in studies aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies.
