Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
IMB-H4 is an antibacterial agent that specifically targets BamA, disrupting the interaction between BamA and BamD. This compound demonstrates significant growth inhibition against various bacterial strains, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. IMB-H4 serves as a valuable tool for research focused on bacterial resistance and the development of novel antibacterial strategies. -
Anti-Bacterial Agent
Elloramycin is an anti-bacterial agent that exhibits weak activity against Gram-positive bacteria and certain leukemic cells, specifically L-1210. Additionally, it demonstrates significant inhibition of Streptomyces activity, including the suppression of their own production. However, it has no effect on mouse leukemic P388 cells in vivo. This compound is relevant for research exploring bacterial inhibition and leukemia treatment alternatives. -
Anti-Bacterial Agent
Senfolomycin A is an anti-bacterial agent that exhibits activity against Gram-positive bacteria and mycobacteria. Notably, it is effective against penicillin-resistant Staphylococcus aureus as well as strains resistant to Streptomycin, Neomycin, and macrolide antibiotics. Senfolomycin A also demonstrates reduced efficacy against Gram-negative bacteria, making it a valuable compound for research in the study of antibiotic resistance and bacterial infections. -
Anti-Bacterial Agent
Leucomycin A6 is an effective anti-bacterial agent targeting Gram-positive bacteria. It exhibits potent antibacterial activity, making it valuable in microbiological research and the study of bacterial infections. Its utility in identifying and characterizing bacterial resistance mechanisms further supports its application in research settings focused on antibiotic efficacy. -
Anti-Bacterial Agent
Cremimycin acts as an anti-bacterial agent with significant activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), demonstrating a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. Additionally, Cremimycin exhibits cytotoxic properties against various mouse tumor cell lines, including P388, L1210, IMC, S180, B16, and SS3 in vitro, making it a valuable compound for cancer research and antibiotic studies. -
Antibacterial Peptide
Plantaricin F is an antibacterial peptide that demonstrates potent inhibitory activity against various gram-negative bacteria, including the foodborne pathogens Salmonella enteritidis and Pseudomonas aeruginosa. Additionally, Plantaricin F effectively targets several species of Lactobacillus, Pediococcus, and Leuconostoc. This reagent is suitable for research applications focused on antibiotic development and the study of antimicrobial peptides. -
Anti-Bacterial Agent
7-O-Isopentenyl-γ-fagarine is an alkaloid derived from Peltostigma guatemalense, known for its antibacterial properties. This compound exhibits significant antimicrobial activity, making it a valuable reagent for research in the development of antibacterial agents and potential therapeutics against various infections. Additionally, it demonstrates antimalarial activities in vitro, contributing to investigations into malaria treatment options. -
Antibacterial Agent
9-Oxonerolidol is a farnesane-type sesquiterpenoid known for its antibacterial properties. Isolated from the plant Chiliadenus lopadusanus, this compound exhibits significant activity against both Gram-positive and Gram-negative bacteria, including strains resistant to conventional antibiotics. It serves as a valuable research tool for studies focused on combating bacterial infections and exploring natural antimicrobial agents. -
Antibacterial Agent
(3R)-7,4’-Dihydrohomoisoflavanone targets bacterial pathogens and exhibits significant antibacterial activity. It has been shown to be effective against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research aimed at developing new antibacterial strategies and understanding the mechanisms of bacterial resistance. -
Antibacterial Inhibitor
HA5 is an antibacterial inhibitor that targets biofilm formation in Streptococcus mutans. It demonstrates a potent inhibitory effect with an IC50 value of 6.42 μM, selectively disrupting biofilm structure without impacting bacterial growth. Additionally, HA5 reduces glucan production and extracellular DNA levels, making it a valuable tool for studying bacterial pathogenesis and potential therapeutic interventions in dental caries research. -
Anthraquinone
Rheoemodin is an anthraquinone compound with notable antibacterial properties. Isolated from Cordyceps morakotii BCC 56811, it demonstrates significant antibacterial activity against Acinetobacter baumannii, with a minimum inhibitory concentration of 12.5 μg/mL. Additionally, Rheoemodin exhibits weak to moderate activity against mycobacterial and fungal pathogens, as well as anticancer effects in breast cancer and small cell lung cancer models. Its diverse biological activities make Rheoemodin a valuable tool for research in microbiology and cancer therapeutics. -
Anti-Neuroinflammatory/Antibacterial Agent
Anti-neuroinflammation agent 2 is an effective anti-neuroinflammatory and antibacterial agent. It exhibits potent inhibition of pro-inflammatory cytokines, with IC50 values of 3.06 µM for TNF-α and 4.31 µM for IL-6. Additionally, it demonstrates antibacterial activity against Gram-positive bacteria, with EC50 values ranging from 0.87 to 3.16 µM. This compound is suitable for research applications targeting neuroinflammatory pathways and microbial infection studies. -
Bacterial Inhibitor
7-O-Methylaloeresin A is a 5-methylchromone glycoside isolated from Commiphora socotrana, acting primarily as a bacterial inhibitor. It demonstrates significant antimicrobial activity against methicillin-resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255), with minimum inhibitory concentrations (MIC) of 0.72 mM and 0.18 mM, respectively. Additionally, 7-O-Methylaloeresin A exhibits antioxidant properties, with IC50 values of 0.026 mM for the DPPH assay and 0.021 mM for the 2-deoxyribose degradation assay, making it useful in studies related to microbial resistance and oxidative stress. -
Antibacterial Agent
Guajaphenone A is a benzophenone glycoside identified as an antibacterial agent, derived from the leaves of Psidium guajava L. It exhibits notable inhibitory effects against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. This compound is valuable for research focused on bacterial infections and the development of antibacterial therapeutics. -
Carbapenem Antibiotic
Tomopenem is a parenteral carbapenem antibiotic known for its extended half-life and broad-spectrum efficacy against various bacterial species. It exhibits potent antibacterial activity with a MIC90 ranging from 0.06 to 4 µg/mL across 293 clinical isolates, effectively targeting both aerobic and anaerobic organisms. Tomopenem is suitable for research applications focused on combating resistant bacterial infections and studying the mechanisms of action of carbapenem antibiotics. -
Antibacterial Agent
Antibacterial Agent 261 is a potent inhibitor of peptidomimetic peptide deformylase (PDF), demonstrating IC50 values of 2.5 nM against Staphylococcus aureus and 10.6 nM against Escherichia coli. This compound exhibits significant antibacterial activity, making it a valuable tool for research focused on combating bacterial infections and understanding bacterial resistance mechanisms. Its efficacy against key pathogens highlights its potential applications in drug development and antibacterial studies. -
Antibacterial Agent
Bromamphenicol is a potent antibacterial agent that functions by binding to the 50S ribosomal subunit, thereby inhibiting peptidyl transferase activity and disrupting protein synthesis. This compound demonstrates significant antibacterial activity and is valuable in research applications involving bacterial infections and antibiotic resistance mechanisms. Its effectiveness in targeting bacterial protein synthesis makes it an essential tool for studying antibiotic efficacy and ribosomal function. -
Antibacterial Peptide
Zaloganan is an antibacterial peptide that functions by disrupting bacterial membranes. This compound displays broad-spectrum antibacterial activity against various pathogens, making it useful in research related to antimicrobial resistance and infection control. Its ability to compromise membrane integrity can provide insights into peptide-mediated mechanisms of action and the development of novel therapeutic agents. -
Antibacterial Agent
Antibacterial agent 199 is an activator of caseinolytic protease (ClpP) with a dissociation constant (Kd) of 0.7 μM. This compound demonstrates significant antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae, as well as the Gram-negative bacterium Neisseria meningitidis, with minimum inhibitory concentrations (MICs) of 16 μg/mL, 0.5 μg/mL, and 0.5 μg/mL, respectively. Antibacterial agent 199 is suitable for studies focused on bacterial resistance and the development of novel antimicrobial therapies. -
Bacterial
Acridine-9-carboxaldehyde is a bioactive compound recognized for its antibacterial and antitumor properties. This reagent serves as an essential building block in the synthesis of diverse bioactive derivatives, facilitating compound development in medicinal chemistry. Additionally, Acridine-9-carboxaldehyde demonstrates notable cytotoxic effects against specific cancer cell lines, positioning it as a valuable candidate for research in cancer inhibition. -
Antibacterial Agent
Antibacterial Agent 37 is a potent antibacterial compound derived from patent WO2015063714A1, specifically compound B. This agent exhibits significant activity against a range of bacterial pathogens, making it suitable for the study of bacterial infections and their mechanisms. It provides researchers with a valuable tool for investigating antibacterial properties and developing potential therapeutic strategies. -
Antibacterial Agent
Macrocarpal E is a phloroglucinol dialdehyde diterpene derivative with demonstrated antibacterial properties. Isolated from the leaves of Eucalyptus macrocarpa, it exhibits significant activity against a range of bacterial strains. This compound is valuable for research focused on antibacterial drug development and the investigation of natural product pharmacology. -
Antibacterial Agent
α-Mycolic acid, keto cis is a structural lipid component of the mycobacterial cell wall, serving as a potential antibacterial agent. Isolated from Mycobacterium tuberculosis Canetti, this compound plays a key role in modulating membrane permeability and stability. Its unique properties make it a valuable tool for research focused on mycobacterial infections, particularly those caused by Mycobacterium tuberculosis. -
Anti-Mycobacterial Agent
BM635 hydrochloride is a potent MmpL3 inhibitor recognized for its exceptional anti-mycobacterial activity. It exhibits a MIC50 of 0.08 μM against Mycobacterium tuberculosis H37Rv, demonstrating significant efficacy in inhibiting bacterial growth. This compound also enhances the in vivo exposure compared to its free base form, making it a valuable reagent for research targeting mycobacterial infections. -
Antibacterial Agent
Antibacterial Agent 169 is a pyrrolamide-based inhibitor targeting GyrB and ParE, demonstrating significant antibacterial activity. It effectively inhibits Gyrase and Topo IV in Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L, respectively. This compound is valuable for research applications focused on combating bacterial infections and exploring mechanisms of antibiotic resistance. -
Antibacterial Agent
NU-3 (Bisphosphocin NU-3) is a potent antibacterial agent that targets bacterial DNA and cell wall integrity. It induces DNA condensation and cell wall deformation, leading to impaired bacterial function. NU-3 is suitable for research applications focused on the pathogenicity of Escherichia coli and Pseudomonas aeruginosa, enabling the investigation of mechanisms underlying bacterial infections and potential therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 83 (compound 17h) acts as a potent antibacterial agent targeting vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). This compound effectively reduces biofilm formation in MRSA and demonstrates promising selectivity against resistant bacterial strains. Additionally, Antibacterial Agent 83 shows metabolic stability in human liver microsomes, making it a valuable candidate for further research in the development of novel antibacterial therapies. -
Antibacterial Agent
BT-33 is a fluorinated macrobicyclic oxepanoprolinamide that functions as a potent antibacterial agent. It exhibits broad-spectrum activity against multidrug-resistant bacterial pathogens, making it a valuable tool for combating infections caused by resistant strains. This compound is particularly useful for research applications aimed at understanding antibacterial mechanisms and developing new therapeutic strategies. -
Anti-Bacterial Agent
11-Hydroxynovobiocin is an anti-bacterial agent that primarily targets Gram-negative bacteria. This compound exhibits potent antibacterial activity, making it suitable for research applications focused on the development of novel antimicrobial therapies. Its efficacy against resistant bacterial strains provides valuable insights into combating bacterial infections. -
Aldehyde Compound
Phellandral is an aldehyde compound primarily sourced from Eucalyptus camaldulensis and Thymus seravschanicus. This compound demonstrates potent antifungal activity, particularly against the plant pathogen Aspergillus flavus. Additionally, phellandral contributes to the antibacterial properties of eucalyptus essential oil, making it valuable for research in phytopathology and natural product development. -
Antibiotic Agent
OES2-0017 is an antibiotic agent that targets spermine/spermidine acetyltransferase (SpeG) with an IC50 of 34.82 μM. This compound exhibits significant activity in inhibiting growth through low micromolar concentrations, demonstrating potent synergy with polyamines. At elevated concentrations, OES2-0017 disrupts bacterial membrane integrity, making it a valuable reagent for investigating bacterial growth inhibition mechanisms and polyamine metabolism in microbial research. -
Bacterial Inhibitor
1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone is a bacterial inhibitor derived from the genus Garcinia. This compound exhibits significant antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentration (MIC) values of 128 μg/mL and 200 μg/mL, respectively. It serves as a valuable tool in research applications aimed at understanding bacterial resistance and developing new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 32 functions primarily as an antibacterial agent, demonstrating potent activity against E. coli strains with minimum inhibitory concentrations (MIC) of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL for NCTC 13351, M 50, and 7 MP, respectively. This compound is valuable for research applications targeting bacterial infections and can be utilized in studies focused on antibiotic resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
Urease-IN-1 is a specific urease inhibitor, demonstrated by an IC50 value of 2.21 ± 0.45 µM. This compound is primarily used for research into bacterial inhibition and is relevant for studies investigating the role of urease in microbial metabolism and pathogenesis. Further applications may include exploring its potential in controlling microbial infections associated with urease-producing bacteria. -
Bacterial Inhibitor
CysHHC10 is a synthetic antimicrobial peptide that acts as a bacterial inhibitor by disrupting the integrity of microbial membranes. This compound demonstrates potent antibacterial activity against a range of both Gram-positive and Gram-negative bacteria, with minimum inhibitory concentrations (MIC) of 10.1 mM for E. coli, 20.2 mM for P. aeruginosa, 2.5 mM for S. aureus, and 1.3 mM for S. epidermidis. CysHHC10 is valuable for research applications focused on combating bacterial infections and studying microbial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 88 (Compound 5h) is a highly effective antibacterial agent that targets a range of bacterial strains. It demonstrates minimal inhibitory concentration (MIC) values of ≤0.0156 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), and Staphylococcus aureus. Additionally, Antibacterial Agent 88 exhibits inhibitory activity against Bacillus subtilis with an MIC of 4 μg/mL. This compound is suitable for research applications focused on bacterial resistance and infection control. -
Bacterial Inhibitor
SCH-538415 is an acyl carrier protein synthase inhibitor that disrupts bacterial cell functions by targeting the AcpS enzyme. It demonstrates significant antibacterial activity, specifically against Staphylococcus aureus, with an IC50 value of 4.19 μM in enzymatic assays. This compound is valuable for research focused on bacterial inhibition mechanisms and the development of new antimicrobial agents. -
Antibacterial Agent
Antimicrobial agent-22 (THI 6c) is a broad-spectrum antibacterial agent that targets multiple pathways within bacterial cells. It exhibits rapid bactericidal activity and demonstrates significant anti-biofilm properties, making it effective in combating bacterial infections. With low cytotoxicity and minimal hemolytic effects, it is suitable for various biological research applications focusing on antimicrobial efficacy and biofilm prevention. -
Bacterial Inhibitor
(±)-Heraclenol is a coumarin compound known for its antibacterial properties. Isolated from the fruits of Angelica lucida, it demonstrates effective inhibition against various bacterial strains. This compound is utilized in research applications focused on understanding bacterial resistance mechanisms and exploring novel antimicrobial agents. -
Antimycobacterial Agent
Tetrahydroxysqualene is a triterpene with demonstrated antimycobacterial activity against Mycobacterium tuberculosis, exhibiting a minimum inhibitory concentration (MIC) of 10.0 μg/mL. This compound can be isolated from the methanolic extracts of Rhus taitensis Guill. Its efficacy makes it a valuable tool for research into possible treatments for tuberculosis and other mycobacterial infections. -
Antibacterial Agent
MC 304 is a β-resorcylate compound derived from the cultures of Phanerochaete chrysosporium, acting primarily as an antibacterial agent. This compound demonstrates significant antibacterial activity, making it valuable for microbiological research. Additionally, MC 304 promotes root elongation in Lepidium sativum, highlighting its potential applications in plant growth studies. -
Anti-bacterial Agent
Kumbicin C is a bis-indolyl benzenoid compound derived from the Australian soil fungus Aspergillus kumbius. This compound primarily functions as an anti-bacterial agent, exhibiting inhibitory effects on the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis. Kumbicin C holds potential applications in antimicrobial research and the development of new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
E 5065 is an orally active antibacterial agent that targets a broad spectrum of microorganisms. This compound exhibits potent in vitro activity against Gram-negative bacteria, Gram-positive cocci, and anaerobes, with an MIC90 of 0.5 μg/mL against Clostridium spp. E 5065 is effective in providing protection against experimental infections caused by Pseudomonas aeruginosa, making it a valuable tool for research in infectious disease and antibiotic efficacy studies. -
Bacterial Inhibitor
Pyrithione sodium primarily targets bacterial inhibition and exhibits antimicrobial properties. This compound is commonly utilized in research applications related to skin microbiome studies and the development of anti-fungal and anti-bacterial treatments. While it is noted for its effectiveness in inhibiting bacterial growth, its limited skin penetration should be considered in experimental designs. -
Anticancer/Anti-inflammatory/Antibacterial Agent
Aspergillumarin A is a dihydroisocoumarin derivative that primarily targets antitumor and anti-inflammatory pathways. It inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 hepatocellular carcinoma cells, making it a valuable tool for cancer research, particularly in studies of hepatocellular carcinoma (HCC). Additionally, Aspergillumarin A demonstrates weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis, supporting its potential use in exploring antibacterial applications. -
Bacterial Biofilm Inhibitor
Antibacterial synergist 1 (compound 20P) is an effective bacterial biofilm inhibitor. It specifically inhibits the production of pyocyanin and biofilm formation in Pseudomonas aeruginosa with IC50 values of 8.6 μM and 4.5 μM, respectively. This compound is valuable for researching therapeutic strategies against P. aeruginosa infections, particularly in the context of chronic infections characterized by biofilm development. -
Antibacterial Agent
Cucurbitacin F is a bioactive compound extracted from Hemsleya gigantha, primarily acting as an antibacterial agent. It exhibits significant antibacterial properties, making it a valuable tool for studies focused on bacterial infections. This reagent can aid in the exploration of antimicrobial mechanisms and the development of new therapeutic approaches in combating bacterial pathogens. -
Bacterial Inhibitor
Eupatarone, also known as Caleprunin B, is a bacterial inhibitor derived from Calea platylepis. This compound exhibits significant antibacterial activity, making it a valuable tool in research focused on combating bacterial infections. Its ability to inhibit bacterial growth positions Eupatarone as an important reagent in microbiological studies and drug discovery efforts targeting antibiotic resistance. -
Antibacterial Agent
Antibacterial agent 106 is a potent antibacterial compound targeting multi-drug resistant Gram-positive pathogens. This orally active agent demonstrates significant antibacterial efficacy, achieving a 99.7% clearance of intracellular methicillin-resistant Staphylococcus aureus (MRSA) within macrophages. Additionally, antibacterial agent 106 features an alkyne moiety, facilitating its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, offering valuable applications in chemical biology and medicinal research. -
Bacterial Inhibitor
Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide derived from Bombina species, primarily functioning as a bacterial inhibitor. This peptide exhibits potent activity against a range of bacterial strains, making it a valuable tool for research in antimicrobial resistance and the development of new therapeutic agents. Its unique mechanism and efficacy position it as an important candidate for studies focused on infection control and peptide-based drug design.
