Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Chevalone B is a bacterial inhibitor derived from the marine sponge-associated fungus Aspergillus similanensis. It exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans and multidrug-resistant environmental strains. Its potential applications in antimicrobial research highlight its significance in the development of novel therapeutic agents. -
Antibacterial Agent
SCH 25393 is a potent antibacterial agent that targets bacterial growth mechanisms. Its biological activity includes inhibiting the proliferation of various bacterial strains, making it valuable for research applications in microbiology and antibiotic resistance studies. This compound serves as a useful tool for investigating the efficacy of new antibacterial therapies and understanding bacterial pathogenesis. -
Antibacterial Agent
Leptosperin is a glycoside derivative of methyl syringate, primarily sourced from manuka honey of the Leptospermum scoparium species. This compound demonstrates notable antibacterial properties, making it a valuable tool for studying bacterial infections and developing potential therapeutic agents. Its unique activity profile may provide insights into the mechanisms of action and efficacy in various infection-related research applications. -
Bacterial
BAS00127538 is a Lipid II inhibitor known for its antibacterial activity. As the first small molecule of its kind, BAS00127538 exhibits a unique structure that differentiates it from naturally occurring Lipid II binders, like vancomycin. Its binding affinity for Lipid II and associated cytotoxicity are critical to its mechanisms of action against bacterial infections. Research applications include investigating its potential as a therapeutic agent in combatting antibiotic-resistant bacterial strains. -
Anti-Bacterial Agent
Dienomycin A is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria and mycobacteria. This compound is valuable in research applications focusing on bacterial infections and antibiotic resistance mechanisms. Its unique mechanism of action makes it a useful tool for studying bacterial physiology and developing new antimicrobial therapies. -
Anti-Bacterial Agent
Pyloricidin A2 is an antibiotic that specifically targets Helicobacter pylori, derived from Bacillus sp. HC-70. This compound exhibits potent antibacterial activity against H. pylori, making it a valuable tool for research into gastric pathogens. Notably, Pyloricidin A2 shows no activity against other bacterial strains or yeast, underscoring its specificity. -
Anti-Bacterial Agent
4"-Demethylgentamicin C1 functions as an anti-bacterial agent, exhibiting potent activity against both Gram-positive and Gram-negative bacteria. Its key biological activity underscores its potential in combating bacterial infections, making it a valuable reagent for microbiological research and applications in antibiotic susceptibility testing. -
Anti-Bacterial Agent
Rifamycin L, an anti-bacterial agent, exhibits potent activity against a variety of Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial RNA synthesis, effectively interfering with transcription processes. This compound is widely utilized in microbiological research to study bacterial resistance mechanisms and to develop new therapeutic strategies against infectious diseases. -
Anti-Bacterial Agent
Oxasetin is an antibacterial agent with selective activity against Gram-positive bacteria, exhibiting a minimum inhibitory concentration (MIC) of 16 μg/mL against Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis. It demonstrates no efficacy against Gram-negative bacteria or fungi. This compound serves as a valuable tool for research focused on combating resistant bacterial infections. -
Antibacterial Agent
(R)-Mucronulatol is a flavonoid with antibacterial properties, primarily isolated from Astragalus adsurgens. This compound exhibits significant antibacterial activity against a range of pathogens, including Escherichia coli, Bacillus cereus, Staphylococcus aureus, Erwinia carotovora, and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 15.5, 15.5, 7.8, 7.8, and 15.5 µg/mL, respectively. Its potential applications include the study of antibacterial mechanisms and the development of new antimicrobial agents. -
Anti-Bacterial Agent
5-Deoxygentamicin C1 is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria. It is commonly utilized in microbiological research to study bacterial resistance mechanisms and the efficacy of antibiotic treatments. This compound serves as a valuable tool for exploring the therapeutic potential of aminoglycosides in combating bacterial infections. -
Antibiotic
Enopeptin A is a depsipeptide antibiotic primarily targeting Gram-positive and certain Gram-negative bacteria. Isolated from Streptomyces sp. RK-1051, it demonstrates potent activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, it exhibits efficacy against mutant strains of Escherichia coli and Pseudomonas aeruginosa, with MICs of 200 μg/mL. Enopeptin A is not effective against fungal pathogens, making it a valuable compound for studies focused on antibiotic resistance and bacterial infections. -
Antibacterial Agent
Antibacterial Agent 279 is a potent antibacterial compound that specifically targets the SOS response in Pseudomonas aeruginosa. This agent exhibits significant antibacterial activity, making it suitable for research focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies. Its efficacy in modulating bacterial stress responses supports studies aimed at understanding and combating multidrug-resistant infections. -
Antimicrobial Agent
Antimicrobial agent-30 is an effective antimicrobial agent that targets various bacterial and fungal strains. It demonstrates minimum inhibitory concentration (MIC) values ranging from 18.7 to 21.0 µg/mL against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger, and Aspergillus fumigatus. This compound is suitable for research applications involving antimicrobial susceptibility testing and the development of new antimicrobial therapies. -
Antibiotic
Phenelfamycins D is an antibiotic derived from the actinobacteria Streptomyces violaceoniger AB 9991-80 and AB 1047T-33. It exhibits potent anti-eutrophic bacterial activity, making it a valuable tool for researching bacterial growth inhibition and antibiotic efficacy. Researchers can utilize Phenelfamycins D to explore its biological mechanisms and potential therapeutic applications in combating bacterial infections. -
Anti-Bacterial Agent
Kigamicin D acts as an effective anti-bacterial agent, demonstrating activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with minimum inhibitory concentrations (MICs) ranging from 0.025 to 0.78 μg/mL. In addition to its antibacterial properties, Kigamicin D exhibits cytotoxicity against L-1210 LB32T and various tumor cell lines, showing an IC50 of 1 μg/mL. This compound is valuable in research focused on combating resistant bacterial strains and investigating therapeutic options for cancer treatment. -
Antibacterial Agent
2-Chloroisonicotinohydrazide is an antibacterial agent primarily targeting Mycobacterium tuberculosis. It demonstrates significant antibacterial activity, exhibiting a MIC50 of 392.0 μM against the H37Rv strain. This compound serves as a valuable tool for research applications focused on tuberculosis and the development of novel therapeutic strategies. -
Anti-Bacterial Agent
Kibdelin C2 is an effective anti-bacterial agent targeting Gram-positive bacteria, exhibiting potent activity against Staphylococcus aureus, including methicillin-resistant strains. Its mechanism of action parallels that of Vancomycin, making it a valuable reagent for research into bacterial resistance and infection treatments. This compound is suitable for studies aimed at exploring novel therapeutic options against resistant bacterial pathogens. -
Antibiotic
Saccharocarcin A is an antibiotic that targets a variety of bacterial and fungal pathogens. It has demonstrated activity against Mycobacterium luteus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans in disc diffusion assays. Additionally, Saccharocarcin A significantly inhibits Chlamydia trachomatis infection by 88% at a concentration of 0.5 μg/mL, while exhibiting low cytotoxicity in McCoy cells, making it a valuable reagent for studying infectious diseases and microbial resistance. -
Bacterial
18:1-14:0 PC is an asymmetric phospholipid that features an unsaturated acyl chain in the sn-1 position. This compound acts as a surfactant, creating a hydrophobic surface in mucus that impedes bacterial penetrance. Additionally, it serves as a dietary source of choline, making it valuable for research applications related to bacterial interactions and membrane dynamics. -
Anti-Bacterial Agent
Cycloheptamycin is an anti-bacterial agent that demonstrates significant activity against Gram-positive bacteria and mycobacteria. Its unique structure allows it to disrupt bacterial cell processes, making it a valuable tool for microbiological research and antibiotic development. This compound is particularly useful in studies focused on combating resistant strains of bacteria. -
Anti-Bacterial Agent
Chimeramycin B is an anti-bacterial agent targeting Gram-positive bacteria and mycoplasma. It exhibits potent inhibitory activity against a range of these microorganisms, making it a valuable tool in microbiological research. This compound is particularly useful in studying bacterial resistance mechanisms and evaluating potential therapeutic applications against infections caused by Gram-positive pathogens. -
Antibacterial Agent
Antibacterial Agent 322 is a potent antibacterial compound that targets and inhibits the growth of various bacterial strains. Its primary mechanism involves disrupting bacterial cell proliferation, making it suitable for research on bacterial infections and the development of new antimicrobial therapies. Utilize Antibacterial Agent 322 to explore bacterial resistance mechanisms and evaluate therapeutic efficacy in preclinical studies. -
Anti-Bacterial Agent
Lycomarasmin is an anti-bacterial agent that targets Lactobacillus casei. This compound exhibits inhibitory effects on the growth of this specific bacterial strain, providing potential applications in microbiological research and the study of bacterial interactions. Its plant-derived nature underscores its utility in exploring natural products for antimicrobial properties. -
Bacterial Ribosome Inhibitor
Capreomycin IA is a bactericidal agent that inhibits bacterial ribosomes, primarily affecting mycobacterial species. By blocking the translocation of peptidyl-transfer RNA from the A to the P site, Capreomycin IA effectively interrupts protein synthesis. This compound demonstrates significant antimicrobial activity against Mycobacterium tuberculosis and is useful for research applications related to tuberculosis and other mycobacterial infections. -
Anti-Bacterial Agent
Pacidamycin 4N is an antibiotic that targets Pseudomonas aeruginosa, exhibiting a minimal inhibitory concentration (MIC) range of 4-16 μg/mL. This compound demonstrates selective antibacterial activity specifically against this pathogen, with no discernible effect on other Gram-negative or Gram-positive bacteria, including drug-resistant strains of Pseudomonas aeruginosa. It is a valuable tool for research on bacterial infections and the development of targeted antimicrobial therapies. -
Anti-Bacterial Agent
Juglomycin A, an anti-bacterial agent, exhibits a broad spectrum of antibacterial and mycobacterial activity. Notably, it has demonstrated efficacy in inhibiting Ehrlich ascites carcinoma in murine models, leading to extended survival rates at a dosage of 1 mg/kg. This compound is of significant interest in research applications aimed at understanding microbial resistance and cancer therapeutic interventions. -
Anti-Bacterial Agent
Paulomenol B is an anti-bacterial agent effective against Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae. This compound exhibits significant inhibitory effects on bacterial growth, making it a valuable tool for research in microbiology and infectious disease. Its application may extend to the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Cephaibol B is an anti-bacterial agent primarily effective against Gram-positive bacteria. This compound exhibits notable anti-bacterial activity while lacking efficacy against Gram-negative strains. In addition to its antibacterial properties, Cephaibol B also demonstrates deworming effects and activity against ectoparasites, making it relevant for research applications in microbiology and parasitology. -
Antibacterial Agent
T145 is an oxazolidinone antibacterial agent that demonstrates potent inhibitory activity against a range of Gram-negative bacteria, including Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter cloacae. It also targets Gram-positive organisms such as Enterococcus faecalis and Staphylococcus aureus, as well as acid-fast pathogens like Mycobacterium abscessus, Mycobacterium avium, and Mycobacterium tuberculosis. This compound is useful in the development of new strategies to combat multi-drug resistant bacterial infections. -
Anti-Bacterial Agent
Nocardicin B is a natural antibacterial agent derived from Nocardia uniformis subsp. tsugamanensis. It exhibits selective antibacterial properties, demonstrating effectiveness primarily against specific Gram-negative bacteria such as Proteus species and axillary bacillus. Research applications include studying its mechanism of action and potential therapeutic roles in combating bacterial infections. -
Anti-Bacterial Agent
Midecamycin A2 is a macrolide antibiotic that exerts its primary antibacterial action against Gram-positive bacteria, demonstrating significant efficacy while showing limited activity against Gram-negative bacteria, mycobacteria, and fungi. This compound is valuable for research applications focusing on the mechanisms of antibiotic resistance, bacterial pathogenesis, and the development of new antimicrobial agents. Its unique profile positions it as a useful reagent in studies involving bacterial infections and treatment strategies. -
Bacterial Metabolite
Leucanicidin is a macrolide bacterial metabolite that targets various pathogenic larvae. Demonstrating significant toxicity, it effectively affects L. separata fourth instar larvae at a concentration of 20 ppm, as well as H. contortus, T. colubriformis, and O. circumcincta larvae, with LD50 values ranging from 0.23 to 0.42 μg/mL. This compound is applicable in research exploring biological pest control and the development of antimicrobial agents. -
Antibacterial Agent
FK 089 is an antibacterial agent that targets bacterial cell function. It exhibits significant antimicrobial activity, making it valuable for research into infection mechanisms and potential therapies. This compound is particularly useful for studies investigating bacterial resistance and the development of new antibacterial strategies. -
Antimycobacterial Agent
Antibacterial Agent 328 is an enoyl-ACP reductase (InhA) inhibitor targeting mycolic acid biosynthesis in Mycobacterium tuberculosis. This compound demonstrates significant activity against both drug-resistant and drug-susceptible strains of M. tuberculosis. With favorable pharmacokinetic properties and a promising safety-related selectivity index, Antibacterial Agent 328 is a valuable tool for research focused on tuberculosis and related infections. -
Antibacterial Agent
CCR-11 is an antibacterial agent that targets bacterial cell division by inhibiting the assembly of FtsZ. It demonstrates potent activity against B. subtilis with an IC50 value of 1.2 μM and is also effective in inhibiting HeLa cell proliferation at an IC50 of 18.1 μM. CCR-11 is a valuable reagent for research focused on FtsZ-targeted antibacterial strategies and the mechanistic understanding of bacterial cytokinesis. -
Anti-Bacterial Agent
6-Deoxyparomomycin is a glycoside antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. Derived from the strain of Streptomyces rimosus forma paromomycinus, it exhibits significant antibacterial activity against a range of Gram-positive and Gram-negative bacteria. This compound is of interest for research into antibiotic mechanisms and the development of novel antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 300 ((S)-3-[4-(Methylthio)phenyl]-2-oxo-5-(aminomethyl)-oxazolidine) is a potent antibacterial compound targeting bacterial protein synthesis. This aminomethyl oxooxazolidinyl benzene derivative exhibits significant antimicrobial activity, making it a valuable tool for research in microbiology and pharmacology. It can be utilized in studies focused on developing new antibacterial therapies and understanding antibiotic resistance mechanisms. -
Bacterial Inhibitor
Timcodar mesylate is a bacterial efflux pump inhibitor that targets multidrug-resistant strains by directly inhibiting ethidium bromide efflux in Staphylococcus aureus. This compound enhances the effectiveness of antibiotic treatments by reducing the minimum inhibitory concentration required against Gram-positive pathogens, including Staphylococcus aureus, Enterococcus, and Streptococcus pneumoniae. Timcodar mesylate serves as a valuable tool in microbial resistance studies and antibiotic synergy research. -
Bacterial
Novobiocic acid is the aglycone form of the antibiotic Novobiocin, targeting bacterial DNA gyrase. This compound exhibits potent antibacterial activity by inhibiting the ATPase activity of the enzyme, thereby disrupting bacterial DNA replication and transcription. Novobiocic acid is widely utilized in microbial research to study antibiotic resistance mechanisms and to evaluate new antibacterial agents. -
Bacterial Inhibitor
Anti-MRSA agent 24 is a potent antimicrobial compound specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with particular efficacy against penicillin-resistant strains. This reagent demonstrates significant antibacterial activity, making it essential for research applications focused on combating resistant bacterial infections and studying mechanisms of antibiotic resistance. -
Bacterial Inhibitor
Streptovitacin A is a potent antibacterial agent derived from microorganisms, designed to inhibit a wide range of bacterial strains and demonstrate antiproliferative effects on tumor cells. Its primary mechanism involves interference with essential bacterial processes, making it a valuable tool in microbiological research and cancer studies. Researchers can utilize Streptovitacin A to explore bacterial resistance mechanisms and evaluate its therapeutic potential in oncology. -
Anti-Bacterial Agent
Chloropolysporin C is an antibacterial agent with potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus species. Its efficacy in inhibiting these pathogens makes it a valuable tool for research related to bacterial resistance and the development of new antimicrobial therapies. Chloropolysporin C is particularly useful in studies focused on combating antibiotic-resistant infections. -
Antibacterial Agent
6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an antibacterial agent that exhibits significant activity against Escherichia coli and Staphylococcus epidermidis, with a minimum inhibitory concentration (MIC) of 10 μg/mL. This compound can be isolated from the plant species Piper obliquum and may serve as a valuable tool for research into antibacterial mechanisms and potential therapeutic applications. -
Anti-Bacterial Agent
Coriolin A is an anti-bacterial agent that demonstrates significant inhibitory activity against Gram-positive bacteria, with some effectiveness against Gram-negative bacteria and yeast, as well as the protozoan Trichomonas vaginalis. At a concentration of 5 μg/mL, it has been shown to inhibit the growth of Yoshida sarcoma by 61.6%. However, Coriolin A does not exhibit inhibitory effects on Ehrlich ascites carcinoma in animal models. Its diverse biological activities make it a valuable reagent for research in antimicrobial therapies and cancer studies. -
Anti-Bacterial Agent
Norplicacetin is an anti-bacterial agent primarily targeting Gram-positive bacteria and mycobacteria. Isolated from Str. plicatus NCIB 11305, it exhibits significant antimicrobial activity, making it a valuable reagent for research into bacterial infections. Its effectiveness against resistant strains can be pivotal in studies aimed at developing new therapeutic strategies in infectious disease management. -
Antibacterial/Antitumor Agent
10-Thiofolic acid is an effective antibacterial and antitumor agent that functions by targeting folate metabolism. This compound demonstrates significant inhibitory activity against Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 7469). Its properties make 10-Thiofolic acid a valuable tool for research focused on leukemia and other related oncological pathways. -
Anti-Bacterial Agent
Amicoumacin C is an anti-bacterial agent that demonstrates moderate activity against various bacterial strains. While its pharmacological effects may be limited, it serves as a valuable tool for research in microbial studies and the development of antibacterial agents. This compound can assist in exploring mechanisms of bacterial resistance and contribute to the identification of new therapeutic targets. -
Anti-Bacterial Agent
Antibiotic U 44590 primarily targets bacterial pathogens as an anti-bacterial agent. It exhibits effective activity against Gram-positive and Gram-negative bacteria, as well as DNA viruses. This compound is valuable for research applications focusing on bacterial resistance mechanisms and the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Saframycin H is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits potent inhibitory activity against mouse lymphocyte L-1210 cells, with an ID50 value of 0.033 μM. This compound is valuable for research applications exploring bacterial infections and immune response mechanisms.
