Puromycin is an aminoglycoside antibiotic that functions as a protein synthesis inhibitor through its action on bacterial ribosomes. By mimicking aminoacyl-tRNA, puromycin interferes with the elongation step of translation, leading to the premature termination of peptide chains. This compound is widely utilized in molecular biology studies, particularly in selection and maintenance of genetically modified cells, as well as in cancer research to elucidate apoptosis pathways.
Puromycin is an aminoglycoside antibiotic that functions as a protein synthesis inhibitor through its action on bacterial ribosomes. By mimicking aminoacyl-tRNA, puromycin interferes with the elongation step of translation, leading to the premature termination of peptide chains. This compound is widely utilized in molecular biology studies, particularly in selection and maintenance of genetically modified cells, as well as in cancer research to elucidate apoptosis pathways.
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