Conimine

Catalog No.: B21828
Antibacterial Agents and Synergist
Conimine is a steroidal alkaloid with significant antibacterial properties, specifically targeting bacteria such as methicillin-sensitive and methicillin-resistant Staphylococcus aureus. Isolated from the seeds of Holarrhena antidysenteriaca, Conimine not only exhibits intrinsic antibacterial activity but also acts as a potentiator. When used in combination with Penicillin or Vancomycin, Conimine enhances the antibacterial efficacy against both strains of Staphylococcus aureus, making it a valuable reagent for research in antibiotic synergy and resistance studies.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionConimine is a steroidal alkaloid with significant antibacterial properties, specifically targeting bacteria such as methicillin-sensitive and methicillin-resistant Staphylococcus aureus. Isolated from the seeds of Holarrhena antidysenteriaca, Conimine not only exhibits intrinsic antibacterial activity but also acts as a potentiator. When used in combination with Penicillin or Vancomycin, Conimine enhances the antibacterial efficacy against both strains of Staphylococcus aureus, making it a valuable reagent for research in antibiotic synergy and resistance studies.
Product Information
Catalog NumB21828
FormulaC22H36N2
Molecular Weight328.53
CAS Number468-41-7
SMILESC[C@H]1[C@]2([H])[C@]3(CN1)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)NC)=CC4)C)([H])CC3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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