Catalog No.
Product Name
Application
Product Information
Citations
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Antitubercular Agent
Antituberculosis agent-8 is a potent antitubercular compound exhibiting a minimum inhibitory concentration (MIC) of 3.53 μM (1.6 μg/mL) against Mycobacterium tuberculosis H37Rv. In addition to its significant antibacterial properties, this compound demonstrates notable antifungal activity against Aspergillus niger, with an MIC of 62.50 μM. It serves as a valuable tool for research in tuberculosis and antifungal studies, aiding in the development of therapeutic strategies for these infections. -
Antifungal Agent
Oosponol is a potent inhibitor of dopamine beta-hydroxylase, known for its hypotensive properties. In addition to its cardiovascular effects, Oosponol displays significant antifungal activity against a wide range of pathogenic fungi. It serves as a valuable reagent for research in antifungal drug discovery and the study of fungal pathogenesis. -
Antifungal Agent
Oxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research. -
Fungicide
Pencycuron is a benzoylurea fungicide that acts by inhibiting the synthesis of fungal cell walls. It exhibits effective antifungal activity against a range of pathogens, including those responsible for sheath blight, powdery mildew, and late blight in crops. Pencycuron is a valuable reagent for research focused on developing strategies for managing fungal diseases in agricultural settings. -
SDH Inhibitor
SDH-IN-25 is a selective inhibitor of succinate dehydrogenase (SDH), with an IC50 value of 4.82 mg/L. This compound displays significant antifungal activity by disrupting respiratory metabolism through its binding to complex II, consequently inducing hyphal morphology changes, generating reactive oxygen species (ROS), and affecting mitochondrial membrane potential (MMP) in fungal mycelia. SDH-IN-25 is suitable for research applications focused on agricultural disease management and the development of novel antifungal strategies. -
Tunicamycin Derivative
Tunicamycin B is a derivative of Tunicamycin known for its antimicrobial properties. It demonstrates significant antibacterial activity against Bacillus thuringiensis strains BT01 and W102, with minimum inhibitory concentrations (MICs) of 0.125 and 0.063 μg/mL, respectively. Additionally, it exhibits antifungal activity against Candida albicans strains ATCC 96901 and CMCC (F) 98001, with MICs of 8.0 and 4.0 μg/mL, respectively. Tunicamycin B is suitable for research applications focused on antimicrobial mechanisms and efficacy. -
Quinine Derivative
Quininone is a quinine derivative that targets various fungal pathogens, exhibiting notable in vitro antifungal activity. This compound is instrumental in antifungal research, facilitating the exploration of novel therapeutic strategies against fungal infections. Its unique chemical properties make it a valuable reagent for scientists investigating the mechanisms of antifungal action and resistance. -
Drug Derivative
Procyanidin A3 is a polyphenolic compound belonging to the proanthocyanidin subclass, characterized by its electrophilic flavanyl unit. This reagent exhibits significant antioxidant and anti-cancer activities and demonstrates anti-inflammatory, cardioprotective, antibacterial, and antifungal properties. Procyanidin A3 is utilized in research applications related to chronic venous insufficiency, capillary fragility, sunburn, and retinopathy, making it a valuable tool for studying its therapeutic potential in various diseases. -
Fungal
PF-184563 is a fungal metabolite derived from the tremorigen-producing fungus Penicillium. This compound exhibits significant neurotoxic properties and is proposed as a potential causative agent of ryegrass spurt disease. PF-184563 serves as an important tool for studying fungal neurotoxicity and its implications in agricultural settings. -
Antifungal Agent
Cascaroside B is a flavonoid known for its antifungal properties, derived from the bacterium Pseudomonas aeruginosa Ld-08. This compound exhibits significant activity against various fungal strains, making it a valuable reagent for studying antifungal mechanisms and developing therapeutic agents. Its application in research can contribute to the understanding of fungal resistance and identification of potential treatment strategies. -
Fungal Inhibitor
Fungicide5 is a potent fungal inhibitor that specifically targets succinate dehydrogenase, exhibiting an inhibitory constant (Ki) of 0.095 μM. This compound is designed for research applications in evaluating antifungal properties and exploring metabolic pathways in fungi. Its selective action makes it a valuable tool for studying fungal biology and developing antifungal strategies. -
Antifungal Agent
Stemphyperylenol is a potent antifungal agent primarily targeting the plant pathogen Alternaria solani, demonstrating an impressive minimum inhibitory concentration (MIC) of 1.57 μM. This compound is useful in studying fungal resistance mechanisms and developing antifungal strategies in agricultural research. Its effectiveness against key plant pathogens highlights its potential for protecting crops from fungal infections. -
Antifungal/Anticancer Agent
Globosuxanthone A is a dihydroxanthenone that exhibits significant antifungal activity against Fusarium graminearum, Fusarium solani, and Botrytis cinerea, displaying minimum inhibitory concentration (MIC) values of 4, 8, and 16 μg/mL, respectively. Additionally, it demonstrates potential anticancer properties, making it a valuable tool for research in both mycology and oncology. This compound can be utilized in studies aimed at developing new antifungal therapies as well as anticancer agents. -
Antifungal Agent
Aminocandin is a water-soluble antifungal agent belonging to the echinocandin class, primarily targeting fungal cell wall synthesis. It demonstrates significant potency against Aspergillus and Candida species, making it a valuable tool for studying antifungal mechanisms and treatments. Its effective inhibition of fungal growth supports research in clinical microbiology and therapeutic development. -
Antibacterial/Antifungal Agent
Sporminarin B is an antibacterial and antifungal agent known for its inhibitory effects on various microorganisms, including Candida albicans and Staphylococcus aureus. It is a valuable candidate for research applications aimed at understanding microbial resistance and developing new therapeutic strategies against bacterial and fungal infections. -
Fungal
Laxifloran is a compound with potent antifungal activity, targeting various fungal pathogens. It demonstrates effective inhibition of fungal growth, making it a valuable reagent for research in mycology and the development of antifungal therapies. Its antibacterial properties further enhance its utility in investigations of microbial interactions and the study of infection dynamics. -
14α-Demethylase Inhibitor
14α-Demethylase-IN-1 is a selective inhibitor of 14α-demethylase, primarily targeting fungal biosynthesis pathways. This compound demonstrates significant antifungal activity, exhibiting MIC50 values of 2.47 μM against C. albicans, 1.23 μM against C. parapsilosis, and 19.70 μM against both C. krusei and C. glabrata over a 48-hour period. 14α-Demethylase-IN-1 is valuable for research focused on antifungal resistance mechanisms and the development of novel antifungal therapies. -
Antifungal Agent
Antifungal Agent 66 is a potent antifungal compound that exhibits broad-spectrum activity against a variety of phytopathogenic fungi. Notably, it demonstrates significant inhibitory effects on the spores of Botrytis cinerea, with an IC50 value of 47.7 μg/mL. This compound is useful for investigating antifungal mechanisms and developing strategies for crop protection against fungal pathogens. -
Antifungal Agent
Chaetoviridin A is an antifungal agent that demonstrates significant activity against various plant pathogens, particularly Verticillium dahliae. It acts by inducing cell necrosis and mycelial deformation, leading to increased sensitivity of V. dahliae to environmental stress. This compound has potential applications in agricultural research, particularly in enhancing cotton growth metrics, such as emergence rate and plant height. -
Antifungal Agent
(±)-Pinoresinol is a potent antifungal agent that targets fungal cell growth and viability. It exhibits significant antifungal activity, making it a valuable reagent for research into fungal pathogenesis and treatment strategies. Its effectiveness in inhibiting fungal proliferation supports its application in studies aimed at understanding fungal infections and developing antifungal therapies. -
Fungicide
Ferbam (Iron(III) dimethyldithiocarbamate) is a potent fungicide that operates by inhibiting the activity of specific enzymes in fungal organisms. It demonstrates significant efficacy against a wide range of fungal pathogens, making it valuable in agricultural research and plant pathology studies. Ferbam is primarily utilized to investigate the mechanisms of fungal resistance and to develop effective fungicidal strategies. -
Pah Inhibitor
Phosphatase-IN-1 is a phosphatidate phosphatase (Pah) inhibitor that selectively targets MoPah1 with an affinity constant of 19.8 μM. This compound demonstrates significant antifungal activity, effectively inhibiting the growth of various plant pathogens. Importantly, Phosphatase-IN-1 exhibits low toxicity towards rice seedlings and wheat heads, making it a valuable tool for research in plant pathology and agricultural applications. -
Antifungal Agent
Antifungal Agent 35 is a potent antifungal compound that enhances the activity of Fluconazole against Candida albicans. This compound functions by inhibiting key fungal pathways, thereby improving therapeutic efficacy. It is suitable for research applications focused on improving antifungal treatments and understanding drug interactions in fungal pathogens. -
Antifungal Agent
Antifungal Agent 58 (Compound A21) is a potent antifungal compound specifically targeting Fluconazole-resistant Candida albicans strains. Demonstrating superior efficacy compared to Miconazole, it exhibits minimal inhibitory concentration (MIC) values ranging from 0.06 to 8 μg/mL. This compound is promising for research applications focused on developing new treatments for antifungal resistance and studying fungal biology. -
Antifungal Agent
γ-Thujaplicin is a naturally occurring compound with antifungal properties derived from the wood of Thujopsis dolabrata. It demonstrates significant cytotoxic effects against human stomach cancer cell lines, including KATO-III and Ehrlich’s ascites carcinoma, while also exhibiting broad-spectrum antifungal activity against wood-rotting fungi. Additionally, γ-Thujaplicin possesses insecticidal effects on harmful insect species. This compound is valuable for research in cancer biology, infectious disease studies, and integrated pest management strategies. -
Antifungal Agent
Antifungal Agent 94, a flavonoid derivative, primarily targets various fungal pathogens. It demonstrates significant antifungal activity with an EC50 of 0.28 μM and a half-maximal effective concentration of 0.46 μg/mL specifically against Rhizoctonia solani. This compound is useful for research in fungal biology and the development of antifungal therapies. -
Anti-Fungal Agent
5-Geranoxy-7-methoxycoumarin is a coumarin derivative exhibiting significant antifungal activity. This compound has demonstrated the ability to induce apoptosis in fungal cells, making it a valuable tool for research into antifungal therapies. Its unique structure and biological properties make it suitable for further investigation in the study of fungal infections and related applications. -
Antiproliferative Agent
Antiproliferative Agent-33 is a potent antiproliferative compound known for its ability to inhibit cell proliferation, particularly in MDA-MB-231 breast cancer cells with an IC50 value of 16.38 μM. Additionally, this compound exhibits antifungal and antibacterial properties, effectively inhibiting growth of gram-negative bacteria and demonstrating a minimum inhibitory concentration (MIC) of 8 μg/mL against Enterococcus faecalis. It is suitable for research applications focused on cancer biology, microbiology, and drug development. -
Antifungal Agent
Hemigossypol is a sesquiterpene natural product derived from Gossypium barbadense, primarily recognized for its antifungal properties. This compound exhibits notable efficacy against various fungal strains, making it valuable for research applications focused on antifungal drug development and the study of fungal pathogenesis. Hemigossypol serves as a useful tool in understanding the mechanisms of fungal resistance and may contribute to the advancement of therapeutic strategies in mycology. -
Fungicidal Agent
FM-678 is a potent fungicidal agent designed to target and inhibit fungal growth. It exhibits exceptional efficacy against Phakopsora pachyrhizi, with an effective concentration (EC50) of 0.14 mg/L. This compound is valuable for research applications involving plant pathology and the development of antifungal strategies. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 13 is a non-competitive inhibitor specifically targeting chitin synthase, demonstrating an IC50 value of 106.7 μM. This compound exhibits broad-spectrum antifungal activity, making it a valuable tool for research in fungal biology and the development of antifungal therapies. Its mechanism of action can provide insights into chitin biosynthesis and contribute to the understanding of fungal cell wall integrity. -
Antifungal Agent
Effusanin B is a diterpenoid compound isolated from Rabdosia effusa (Maxim.) Hara, exhibiting potent antifungal properties. This compound targets fungal cell membrane integrity, making it a valuable tool for researching antifungal mechanisms and developing new therapeutic strategies against fungal infections. Its unique structure and biological activity provide opportunities for exploring applications in pharmacology and mycology. -
Fungal
Janthitrem F is a metabolite derived from the tremorigenic fungus Penicillium, primarily targeting fungal pathways. This compound is associated with inducing neurological effects in mammals and is investigated for its potential role in ryegrass spurt disease pathology. Janthitrem F serves as a valuable tool in studying fungal metabolites and their impacts on animal health. -
Antifungal Agent
(4S)-(+)-Ascochin serves as an antifungal agent primarily targeting Microbotryum violaceum, Phytophthora infestans, and Septoria tritici. Additionally, it demonstrates antialgal activity against Chlorella fusca. This compound is valuable for research in plant pathology and the study of fungal-algal interactions. -
antifungal agent
Croconazole is an antifungal agent that features imidazole rings with an aryl vinyl substituent at the N-1 position. This compound exhibits potent antifungal activity, making it useful for research on fungal infections. Additionally, Croconazole can be utilized for the identification and quantitative analysis of major metabolites in rat urine and bile, aiding in pharmacokinetic studies. -
Antifungal Drug
Rabdoserrin A is a diterpenoid known for its antifungal properties. This compound demonstrates significant activity against various fungal pathogens, making it a valuable tool in the study of antifungal mechanisms and the development of antifungal therapies. Researchers can utilize Rabdoserrin A in assays aimed at understanding fungal resistance and evaluating the efficacy of novel antifungal agents. -
Fungal Inhibitor
Bac2A TFA is an antimicrobial peptide that acts as a potent inhibitor of fungal pathogens. This linear variant of bactenecin exhibits significant antifungal activity, making it suitable for research applications focused on fungal infections and immunomodulation studies. Its unique properties offer potential insights into host-pathogen interactions and the development of novel therapeutic strategies against fungal diseases. -
Antifungal Agent
Antifungal agent 32 primarily targets Candida albicans, exhibiting potent antifungal activity. This compound effectively inhibits filamentation and biofilm formation, preventing morphological switching and adherence to epithelial cells. Antifungal agent 32 serves as a valuable tool for research focused on Candida albicans infections and related antifungal treatments. -
Antifungal Agent
(+)–Pinoresinol diacetate is an antifungal agent that targets fungal cells by disrupting membrane integrity. Isolated from Sambucus williamsii, it exhibits significant antifungal activity, making it a valuable compound for studying fungal infections. This reagent is applicable in research focused on developing novel antifungal therapies and understanding antifungal mechanisms. -
Antifungal Antibiotic
Echinocandin B is an antifungal antibiotic that targets the synthesis of β-glucan in the fungal cell wall. It exhibits potent activity against a variety of pathogenic fungi, making it a valuable reagent in antifungal research. This compound is particularly useful for studying fungal infections and evaluating the efficacy of new antifungal therapies. -
Antifungal Agent
Ys-II is a spirostanol glycoside derived from the stem of Yucca elephantipes, exhibiting significant antifungal activity. It demonstrates inhibitory effects against Candida albicans and Cryptococcus neoformans, with IC50 values of 5 μg/mL and 6 μg/mL, respectively. This compound is useful in research applications focused on fungal infections and the exploration of potential antifungal therapies. -
Chitin Synthase Inhibitor
Chitin Synthase Inhibitor 5 specifically targets chitin synthase, demonstrating an IC50 value of 0.14 mM. This compound exhibits broad-spectrum antifungal activity in vitro, effectively inhibiting the growth of Candida albicans, Aspergillus flavus, Aspergillus fumigatus, and Cryptococcus neoformans. Chitin Synthase Inhibitor 5 is valuable for research focused on fungal pathogenesis and potential therapeutic strategies against fungal infections. -
Fungal Inhibitor
Deoxyviolacein is a bacterial metabolite that acts as a potent fungal inhibitor. It demonstrates significant antifungal activity against Rhizoctonia solani at a concentration of 2 mg/mL. Additionally, Deoxyviolacein exhibits antibacterial properties against Gram-positive bacteria, such as Staphylococcus aureus, Bacillus subtilis, and Bacillus megaterium, with effective inhibition observed at 125 μg/mL. This compound has potential applications in cancer research, particularly in inhibiting the proliferation of hepatocellular carcinoma cells at concentrations ranging from 0.1 to 1 μM. -
Fungicide
Metalaxyl-M-d6 is a deuterium-labeled derivative of Metalaxyl-M, a selective inhibitor of fungal RNA polymerase. This compound exhibits potent fungicidal activity by obstructing the synthesis of fungal ribosomal RNA. In addition to its primary function as a fungicide, Metalaxyl-M-d6 is utilized in studies involving inflammation in hepatocytes and the regulation of tryptophan metabolism. Furthermore, it serves as a valuable reagent in ecotoxicology research. -
Antifungal Agent
Eberconazole is a dichlorinated imidazole derivative that exerts its antifungal activity by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This compound demonstrates significant effectiveness against dermatophytes, making it a valuable tool for research in dermatophytosis and other fungal infections. Eberconazole's unique mechanism of action supports its application in studying antifungal therapies and resistance mechanisms in pathogenic fungi. -
Antifungal Agent
Antifungal agent 127 is an antifungal compound that targets a broad spectrum of fungal pathogens. It demonstrates potent inhibitory activity against Botrytis cinerea, Rhizoctonia solani, and various other fungal species. This compound is valuable in research applications aimed at understanding fungal infections and developing effective antifungal treatments. -
Antifungal Agent
Trianthenol is a tetraterpenoid compound that functions as an antifungal agent. It exhibits significant inhibitory activity against various fungal pathogens, making it a valuable tool for research in mycology and the development of antifungal therapies. Isolated from the whole plant of Trianthema portulacastrum, Trianthenol serves as a potential candidate for studies aimed at understanding fungal resistance mechanisms and exploring new antifungal treatments. -
Anthraquinone Fungicide
Dithianon is a broad-spectrum anthraquinone fungicide that exhibits strong adhesion to the surfaces of leaves and fruits. It effectively controls various fungal pathogens, including anthracnose caused by Colletotrichum spp. and Elsinoe ampelina, as well as mildew due to Plasmopara viticola and phomopsis infections in Phomopsis viticola. This compound is widely utilized in agricultural research to enhance crop protection and improve yield by mitigating fungal disease incidence in fruits and vegetables. -
Antifungal Agent
Antifungal Agent 27 primarily targets fungal pathogens exhibiting antifungal activity. This compound demonstrates moderate antibacterial effects against Methicillin-Resistant Staphylococcus aureus (MRSA) and weak antifungal activity against Candida albicans SS5314, with minimal inhibitory concentration (MIC) values of 8 μg/mL and 32 μg/mL, respectively. It is suitable for research applications focusing on the development of novel antifungal therapies and the study of resistance mechanisms in pathogenic microbes. -
Antifungal Agent
2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin with notable antifungal properties, primarily targeting fungal pathogens. Isolated from the root tissue of Sanguisorba minor, this compound demonstrates strong inhibition of spore germination in Botrytis cinerea, making it valuable for research into antifungal mechanisms and plant defense responses. Its biological activity supports investigations into natural compounds for enhancing plant resistance to fungal infections.
