Catalog No.
Product Name
Application
Product Information
Citations
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Antifungal Agent
Antifungal Agent 31 is a potent triazole antifungal agent that targets fungal cell membranes through inhibition of ergosterol biosynthesis. It exhibits significant antifungal activity against various Candida species and filamentous fungi. In preclinical studies using murine models, Antifungal Agent 31 demonstrated a marked reduction in mortality rates and kidney fungal burden, highlighting its potential in treating lethal systemic fungal infections. -
Volatile Organic Compound
Cis-3-Hexenyl benzoate is a volatile organic compound primarily utilized in fragrance and cosmetic applications due to its characteristic grassy aroma. This compound displays weak antifungal properties, making it suitable for various formulations. Additionally, cis-3-Hexenyl benzoate has an established safety profile, with negligible risks related to genotoxicity, reproductive toxicity, and environmental toxicity, while its skin sensitization potential is manageable within specified concentration limits. -
Secondary Metabolite
Neoaspergillic acid is a microbial secondary metabolite primarily isolated from the endophytic fungus Aspergillus sp. SPH2. It exhibits potent antifungal activity against several plant pathogens, including Alternaria alternata, Botrytis cinerea, and Fusarium oxysporum. Additionally, neoaspergillic acid demonstrates antitumor and antibacterial properties, making it a valuable compound for research in antifungal therapeutics and disease management in agricultural applications. Its presence during the exponential growth phase of fungi further highlights its significant biological role. -
Antifungal Agent
Antifungal agent 47 is a potent fungicide that acts by inhibiting adenosine 5'-triphosphate synthesis, resulting in robust respiratory inhibition across a variety of fungal strains. Its broad-spectrum fungicidal activity makes it suitable for research applications aimed at understanding fungal resistance mechanisms and developing new treatments for fungal infections. This compound is a valuable tool for exploring antifungal pharmacology and potential therapeutic interventions. -
Anti-fungal Agent
1,3,6-Trihydroxy-5-methoxyxanthone is a natural compound known for its anti-fungal properties. Isolated from the root bark of Tovomita krukovii, it exhibits significant inhibitory effects against various fungal pathogens. This compound is valuable for research applications focused on fungal infections and the development of new antifungal agents. -
Defensin-like Antifungal Peptide
Gymnin is a defensin-like antifungal peptide that exhibits notable antifungal activity against both phytopathogenic and mycotoxigenic fungi. Additionally, Gymnin inhibits HIV-1 reverse transcriptase with an IC50 of 200 μM and suppresses tumor cell proliferation, although it demonstrates only weak mitogenic activity in murine splenocytes. This compound is suitable for research applications related to plant disease treatment and the exploration of antifungal mechanisms. -
Fungal
(Rac)-Paclobutrazol-15N3 is a nitrogen-15 isotopically labeled derivative of Rac-Paclobutrazol, primarily targeting fungal organisms. This reagent is utilized in studying the metabolic pathways and ecological interactions of fungi, enabling researchers to trace compound distribution and assess its biological impacts in various environments. Its applications include research in plant-fungal interactions, agricultural science, and biochemistry related to fungal inhibition. -
Anti-fungal Agent
Guignardone K is a meroterpene compound derived from the endophytic fungus Guignardia sp. This compound exhibits potent antifungal activity, making it a valuable tool for research focused on fungal infections and the development of novel antifungal agents. Its mechanism of action contributes to an enhanced understanding of fungal biology and potential therapeutic strategies. -
Anti-fungal Triterpene Saponin
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin targeting fungal cell membranes. Derived from the aerial parts of Clematis tangutica, this compound demonstrates significant antifungal activity against various strains, including P. avellaneum, C. glabrata, S. cerevisiae, and T. beigelii, with the most pronounced effect noted against S. cerevisiae. Its bioactivity makes it a valuable reagent for studies investigating antifungal mechanisms and potential therapeutic applications. -
Antifungal Agent/C-4 Sterol Methyl Oxidase Inhibitor
PF-1163A is an antifungal agent that functions as a C-4 sterol methyl oxidase inhibitor, effectively disrupting ergosterol synthesis with an IC50 of 12 ng/mL. This compound demonstrates notable antifungal activity, characterized by a minimum inhibitory concentration (MIC) of 12.5 µg/mL. PF-1163A is valuable for research applications focused on fungal infections and the mechanistic understanding of ergosterol biosynthesis. -
Antifungal Agent
Antifungal Agent 125 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 3.59 μg/mL. This compound exhibits significant fungicidal activity against the fungal pathogen Alternaria alternata, making it a valuable tool for research in antifungal mechanisms and treatments. Its specific action on SDH positions it as a candidate for further exploration in the development of antifungal strategies. -
Chitin Deacetylase Inhibitor
AnCDA-IN-1 is a selective inhibitor of chitin deacetylase (CDA), demonstrating significant antifungal properties. It exhibits an IC50 value of 4.24 μM against AnCDA from Aspergillus nidulans and shows a minimum inhibitory concentration (MIC) of 260 μg/mL against various food spoilage and plant pathogenic fungi, with a minimum fungicidal concentration (MFC) of 520 μg/mL. This compound is valuable for research in the antifungal domain, particularly in understanding CDA's role in fungal cell wall integrity and potential therapeutic applications. -
Fungicide
Furmecyclox is a potent fungicide targeting basidiomycetes. It exhibits significant antifungal activity, making it suitable for both agricultural and laboratory applications in managing fungal diseases. Furmecyclox can be used to investigate the mechanisms of fungal growth inhibition and is essential for research focusing on mycology and plant pathogenesis. -
Fungal
3',5,5'-Trichlorosalicylanilide (TCSA) primarily inhibits fungal morphogenesis by disrupting key developmental processes. This compound effectively prevents biofilm formation and restricts the ability of fungi to invade host cells. TCSA is valuable in researching antifungal mechanisms and developing potential therapeutic strategies against fungal infections. -
Antimycotic Agent
Buclosamide is an antimycotic agent that exhibits potent antifungal activity by inhibiting the growth of various pathogenic fungi. It is primarily used in topical formulations to treat fungal infections of the skin and mucous membranes. Its efficacy in targeting fungal pathogens makes it a valuable tool in dermatological research and therapeutic applications. -
Antifungal Agent
SDZ89-485 is an orally active triazole antifungal agent that targets fungal cells, specifically disrupting ergosterol biosynthesis. In preclinical studies, SDZ89-485 demonstrated a superior antifungal effect against spore-forming fungi in mouse models, despite lower peak concentrations compared to traditional therapies. This compound is suitable for research applications focused on antifungal activity and mechanisms of resistance in fungal pathogens. -
Antifungal Agent
Antifungal agent 77 (Compound 13h) primarily targets fungal pathogens, exhibiting potent antifungal activity. At a concentration of 500 μg/mL, it demonstrates noteworthy insecticidal effects against various pests, including Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda, resulting in mortality rates of 30%, 25%, 40%, and 25%, respectively. Additionally, antifungal agent 77 exhibits toxicity in zebrafish embryos with a calculated LC50 of 2.43 μg/mL, highlighting its potential implications in ecological toxicology studies. -
Antifungal and Antiparasitic Agent
Oleylphosphocholine is an orally active antifungal and antiparasitic agent targeting invasive fungal infections and parasitic diseases. It demonstrates significant efficacy in the treatment of conditions such as aspergillosis and visceral leishmaniasis. This compound is valuable for research focused on developing therapeutic strategies against these challenging infectious diseases. -
Antifungal Agent
Antifungal Agent 25 is a potent broad-spectrum antifungal compound that targets various fungal pathogens. It exhibits significant antifungal activity against Candida albicans, including strains resistant to fluconazole. Additionally, this agent demonstrates stable metabolic properties in vivo, making it a valuable tool for researching antifungal mechanisms and potential therapeutic applications in fungal infections. -
Antifungal Agent
N-(2-hydroxy-2-phenylethyl)acetamide is an antifungal agent derived from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. This compound demonstrates significant antifungal activity against Alternaria solani, making it a valuable tool in the study of fungal pathogens. Its properties aid in the exploration of antifungal mechanisms and potential therapeutic applications in combating fungal infections. -
Antifungal Agent
[6]-Gingerdiol is an antifungal agent primarily derived from Zingiber officinale. It demonstrates effective antifungal activity against M. gypseum, exhibiting a minimum lethal concentration (MLC) of 422 μg/mL. This compound holds potential for research applications focused on developing antifungal therapies and studying fungal resistance mechanisms. -
Sesquiterpenoid
1β-Acetoxypolygodial is a sesquiterpenoid derived from Tasmannia lanceolata, exhibiting significant biological activity against cancer cells and fungal pathogens. Its properties make it a valuable tool for investigating therapeutic strategies in oncology and mycology research. The compound can be utilized in studies exploring its mechanisms of action and potential as a lead compound for drug development. -
Antifungal Agent
Bitertanol is a potent antifungal agent that targets various fungal species through inhibition of fungal sterol synthesis. It has demonstrated activity against a broad spectrum of fungi and is utilized in research applications involving antifungal drug development. Additionally, Bitertanol acts as an inducer of CYP1A1, CYP2B, and CYP3A in vivo, while inhibiting CYP1A in vitro, highlighting its relevance in studying cytochrome P450 enzyme interactions. -
Antifungal Agent
LW3 is a potent antifungal agent that targets a variety of fungal pathogens. It exhibits significant antifungal activity with EC50 values of 0.54 mg/L against Botrytis cinerea, 0.09 mg/L against Rhizoctonia solani, 1.52 mg/L against Sclerotinia sclerotiorum, and 2.65 mg/L against Fusarium graminearum. This compound is valuable for research applications aimed at developing effective treatments for fungal infections in agriculture and plant pathology. -
Antifungal Agent
Savirin is an antifungal agent that demonstrates potent in vitro antibacterial and antibiofilm properties. This compound has been shown to prevent skin infections caused by Staphylococcus aureus in vivo. Additionally, Savirin displays increased efficacy when used in combination with antibiotics, making it a valuable tool for research in microbial resistance and skin infection treatment. -
Antifungal Agent
Decussatin is an α-Amylase inhibitor derived from the Tibetan medicinal plant Swertia mussotii. By inhibiting the enzymatic activity of α-Amylases, Decussatin effectively reduces the hydrolysis of complex carbohydrates, leading to decreased glucose absorption in the intestines and lower blood glucose levels. While it demonstrates limited antibacterial and antifungal properties, Decussatin is primarily utilized in the study of type 2 diabetes and its management. -
Hyphal Formation Inhibitor
2-Dodecanol is an effective hyphal formation inhibitor with targeted activity against Candida albicans. By inhibiting SIR2 expression, it disrupts the morphological transition essential for pathogenicity. This compound is valuable for researchers studying fungal biology and the mechanisms of infection, as well as for developing potential antifungal strategies. -
Phytoalexin
Avenanthramide L is a phytoalexin that targets fungal spores, specifically inhibiting the germination of Puccinia coronata f. sp. avenae. Detected in infected Avena sativa L. leaves, it demonstrates significant antifungal activity with approximately 50% inhibition at concentrations of 200-300 μg/mL. Notably, Avenanthramide L is not present in healthy oat seedlings, making it a valuable tool for investigating oat crown rust resistance mechanisms. -
Glutamate Transport Inhibitor
Avenaciolide is a bis-γ-lactone derived from Aspergillus avenaceus that acts as a specific inhibitor of glutamate transport. This compound demonstrates antifungal and antibacterial properties while also interfering with the stimulatory effect of ADP on glutamate oxidation in rat liver mitochondria. Avenaciolide's unique mechanism makes it valuable for studying metabolic processes and the regulation of glutamate transport in cellular and mitochondrial contexts. -
Antifungal Agent
Nystatin A2 is a polyene antifungal antibiotic that targets fungal cell membrane integrity by binding to ergosterol. It exhibits potent activity against various yeast and mycoplasma strains, making it invaluable for research in mycology and antibiotic efficacy studies. This compound is particularly useful for investigating antifungal mechanisms and developing treatment strategies against fungal infections. -
Phosphomannose Isomerase
Phosphomannose isomerase is a key enzyme that catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate, playing a vital role in the biosynthesis of GDP-mannose. This enzyme is crucial for cell wall synthesis and protein glycosylation processes. Targeting phosphomannose isomerase offers potential in antifungal research, particularly in addressing challenges posed by Aspergillus flavus. Its inhibition may provide insights into novel therapeutic strategies against fungal infections. -
Antifungal Agent
BI-10 is an antifungal agent that demonstrates potent inhibitory effects on hyphal growth. When used in combination with Fluconazole, BI-10 promotes reactive oxygen species (ROS) accumulation, leading to a decrease in mitochondrial membrane potential (MMP) and altered membrane permeability. This makes BI-10 a valuable tool for researching antifungal mechanisms and evaluating therapeutic strategies against fungal pathogens. -
Antimicrobial Agent
(Rac)-CPI-098 is an antimicrobial agent with demonstrated antibacterial properties. It exhibits significant antifungal activity, particularly against Monascus ruber, and shows enhanced efficacy against Aspergillus fumigatus. Additionally, (Rac)-CPI-098 displays good activity against Aspergillus niger and Aspergillus species, while maintaining moderate effectiveness against Candida albicans. This compound is suitable for research applications focused on antimicrobial efficacy and fungal pathogenicity. -
Succinate Dehydrogenase Inhibitor
SDH-IN-3 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 of 7.2 μg/mL. This compound exhibits significant antifungal activity against Nigrospora oryzae, with an EC50 of 1.9 μg/mL. SDH-IN-3 is suitable for research applications focused on anti-infection studies and the modulation of metabolic pathways in fungal pathogens. -
Metabolite
Nidulol is a metabolite derived from the fungus Aspergillus nidulans. This compound exhibits a lack of phytotoxic activity against Zea mays and Medicago polymorpha L. at a concentration of 5 mM, making it a valuable tool for studying plant-fungal interactions and assessing biocompatibility in agricultural research. Its unique properties may provide insights into fungal metabolic pathways and their potential applications in biotechnology. -
Picolinic Acid Derivative
Penicolinate B is a picolinic acid derivative with significant biological activity. It demonstrates potent antimalarial properties (IC50: 1.40 μg/mL), along with effective antitubercular activity (MIC: 25.0 μg/mL) and inhibition of Bacillus cereus (IC50: 25.0 μg/mL). Additionally, it shows antifungal activity against Candida albicans (IC50: 1.45 μg/mL) and exhibits cytotoxic effects on cancer cell lines, including MCF-7, KB, and NCI-H187. This compound is useful in research focused on malaria, tuberculosis, bacterial and fungal infections, as well as cancer. -
Antifungal Agent
1-Heptadecene is a long-chain hydrocarbon with demonstrated antifungal and antibacterial properties. Isolated from the metabolite profile of Aporosa cardiosperma, it serves as a valuable tool in research exploring novel antimicrobial agents. Its efficacy against various fungal strains makes it a suitable candidate for studies focusing on infection control and the development of antifungal therapies. -
Triazole Fungicide
Triadimenol is a triazole fungicide that inhibits sterol biosynthesis in fungi, disrupting cell membrane integrity. This compound exhibits effective antifungal activity against a range of pathogens, making it valuable for agricultural research focused on crop protection. Additionally, Triadimenol's toxicity to non-target organisms underscores the importance of careful application and environmental assessment in agricultural practices. -
SARS CoV-2 3CLpro Inhibitor
SARS-CoV-2 3CLpro-IN-4 is a potent inhibitor of the SARS-CoV-2 3CL protease, a critical enzyme for viral replication. This compound exhibits significant antiviral activity, making it relevant for research in COVID-19 therapeutics. Its broad-spectrum impact also extends to antibacterial and antifungal activities, aiding investigations into multi-faceted infectious disease mechanisms. -
Antifungal Agent
Cytosporone C is an antifungal metabolite derived from the fungus Diaporthe eucalyptorum, associated with Melia azedarach. This compound demonstrates potent antifungal activity against Alternaria solani, making it valuable for research in fungal pathogenesis and therapeutic development. Its efficacy in inhibiting fungal growth positions Cytosporone C as a promising candidate for studying antifungal mechanisms and potential treatments. -
Ras Inhibitor
Antifungal agent 46 is a potent Ras inhibitor that targets protein farnesyltransferase, effectively disrupting Ras signaling pathways. This compound demonstrates significant antifungal activity and holds potential for research applications focused on understanding Ras-related mechanisms in fungal infections. Studies may explore its utility in elucidating the role of Ras in cellular signaling and its implications in therapeutic developments. -
Antimicrobial
Monogalactosyl diglyceride is an antimicrobial compound that exhibits both antibacterial and antifungal activity in vitro. It is primarily utilized in research focused on understanding the mechanisms of microbial inhibition and the development of novel antimicrobial agents. Its ability to disrupt microbial cell membranes makes it a valuable tool in pharmaceutical and biomedical investigations. -
Fungal Inhibitor
Antibacterial agent 188 is a potent fungal inhibitor that targets dermatophyte activity. This compound demonstrates significant antifungal properties, making it suitable for research applications focused on fungal infections and dermatological studies. Its mechanism of action involves disrupting fungal cell processes, thereby inhibiting growth and proliferation. -
Fungal
Bivittoside A is a non-sulfated hexoside analog derived from the bovine sea cucumber, primarily targeting fungal pathogens. This compound exhibits significant antifungal activity, making it a valuable tool for research into fungal infections. Additionally, Bivittoside A shows potential for antitumor applications, highlighting its versatility in cancer research. -
Succinate Dehydrogenase Inhibitor
Harzianopyridone is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 80 nM. Isolated from the fungus Trichoderma harzianum, this compound demonstrates significant antifungal, antibacterial, and herbicidal properties. Harzianopyridone is valuable for research applications exploring metabolic modulation and the study of fungal and bacterial pathways. -
Gamma-Glutamyl Transferase Inhibitor
Gamma-Glutamyl Transferase-IN-1 is a potent inhibitor of gamma-glutamyl transferase, specifically designed to disrupt its enzymatic function. This β-carboline 1-hydrazide compound exhibits significant antifungal and antibacterial activities by promoting the accumulation of reactive oxygen species, leading to cell membrane disruption and alterations in histone acetylation. It serves as a valuable tool for research investigating the roles of gamma-glutamyl transferase in various biological processes and disease states. -
Antiproliferative/Antimicrobial Agent
Antiproliferative agent-18 is an anti-proliferative compound that exhibits significant effects in inhibiting cell growth. This agent also exhibits moderate antibacterial and antifungal properties, making it valuable for research in microbiological studies and cancer treatment. Its diverse biological activity positions it as a useful tool for scientists exploring cellular proliferation and antimicrobial mechanisms. -
Antifungal Agent/LOX-1 Inhibitor
Sclerotiorin is a reversible uncompetitive inhibitor of soybean lipoxygenase-1 (LOX-1), with an IC50 value of 4.2 μM. This compound exhibits significant antioxidant activity by scavenging free radicals (ED50: 0.12 μM) and inhibiting nonenzymatic lipid peroxidation. Additionally, Sclerotiorin demonstrates antifungal properties and the ability to inhibit platelet aggregation. It can be isolated from the fermented broth of Penicillium frequentans, making it a valuable reagent for research in antifungal mechanisms and oxidative stress studies. -
SDH Inhibitor
SDH-IN-18 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 8.70 mg/L. This compound demonstrates significant antifungal activity, disrupting the morphology and reproduction of fungi. It is particularly effective against Rhizoctonia solani and Sclerotinia sclerotiorum, with EC50 values of 0.48 mg/L and 1.4 mg/L, respectively. SDH-IN-18 can be utilized in research studying fungal pathology and SDH-related metabolic pathways. -
Antifungal Drug
Isobellidifolin is a xanthone that acts as a free radical scavenger and antioxidant. It exhibits significant antifungal activity, making it a valuable compound for research applications focused on fungal infections and oxidative stress. This compound may be useful for studying mechanisms of antifungal resistance and the development of novel antifungal therapies.
