14α-Demethylase-IN-1 is a selective inhibitor of 14α-demethylase, primarily targeting fungal biosynthesis pathways. This compound demonstrates significant antifungal activity, exhibiting MIC50 values of 2.47 μM against C. albicans, 1.23 μM against C. parapsilosis, and 19.70 μM against both C. krusei and C. glabrata over a 48-hour period. 14α-Demethylase-IN-1 is valuable for research focused on antifungal resistance mechanisms and the development of novel antifungal therapies.
14α-Demethylase-IN-1 is a selective inhibitor of 14α-demethylase, primarily targeting fungal biosynthesis pathways. This compound demonstrates significant antifungal activity, exhibiting MIC50 values of 2.47 μM against C. albicans, 1.23 μM against C. parapsilosis, and 19.70 μM against both C. krusei and C. glabrata over a 48-hour period. 14α-Demethylase-IN-1 is valuable for research focused on antifungal resistance mechanisms and the development of novel antifungal therapies.
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