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Ys-II

Catalog No.: A27731
Antifungal Agent
Ys-II is a spirostanol glycoside derived from the stem of Yucca elephantipes, exhibiting significant antifungal activity. It demonstrates inhibitory effects against Candida albicans and Cryptococcus neoformans, with IC50 values of 5 μg/mL and 6 μg/mL, respectively. This compound is useful in research applications focused on fungal infections and the exploration of potential antifungal therapies.
Ys-II 897386-27-5 Antifungal Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionYs-II is a spirostanol glycoside derived from the stem of Yucca elephantipes, exhibiting significant antifungal activity. It demonstrates inhibitory effects against Candida albicans and Cryptococcus neoformans, with IC50 values of 5 μg/mL and 6 μg/mL, respectively. This compound is useful in research applications focused on fungal infections and the exploration of potential antifungal therapies.
Product Information
Catalog NumA27731
FormulaC45H76O19
Molecular Weight921.07
CAS Number897386-27-5
SMILESC[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H](C(O)(O3)CC[C@@H](C)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)([H])[C@@]5([H])[C@]([C@@]6([C@](C[C@H](CC6)O[C@H]7[C@@H]([C@H]([C@H]([C@H](O7)CO)O)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)([H])CC5)C)([H])CC1
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Microbiology > Antifection > Fungal