Oxiconazole

Catalog No.: A27674
Antifungal Agent
Oxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research.
Grouped product items
Size Price Stock Qty
1mg
$235.00
In stock
5mg
$590.00
In stock
10mg
$830.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOxiconazole is a broad-spectrum antifungal agent that effectively inhibits the growth of various fungi, including Candida, Aspergillus, and Trichophyton. In addition to its antifungal properties, Oxiconazole serves as a potent activator of CYP3A4 transactivation, with potential competitive antagonism by Rifampicin. Furthermore, Oxiconazole demonstrates an inhibitory effect on colorectal cancer through the mediation of peroxiredoxin-2 (PRDX2)-induced autophagy arrest, highlighting its potential application in cancer research.
Product Information
Catalog NumA27674
FormulaC18H13Cl4N3O
Molecular Weight429.13
CAS Number64211-45-6
SMILESClC1=CC=C(/C(CN2C=CN=C2)=N/OCC3=CC=C(Cl)C=C3Cl)C(Cl)=C1
SynonymsRo 13-8996 free base
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