SS-750 is an orally active triazole derivative that functions as an antifungal agent by binding to fungal cytochrome P450 enzymes. This compound exhibits potent antifungal activity against various Candida species, including C. parapsilosis, C. krusei, and C. glabrata, with MIC90 values of 0.25, 1, and 2 μg/mL, respectively. Additionally, SS-750 demonstrates efficacy in improving systemic and pulmonary infections caused by C. albicans. Its profile makes SS-750 a valuable reagent for research into antifungal therapies and resistance mechanisms.
SS-750 is an orally active triazole derivative that functions as an antifungal agent by binding to fungal cytochrome P450 enzymes. This compound exhibits potent antifungal activity against various Candida species, including C. parapsilosis, C. krusei, and C. glabrata, with MIC90 values of 0.25, 1, and 2 μg/mL, respectively. Additionally, SS-750 demonstrates efficacy in improving systemic and pulmonary infections caused by C. albicans. Its profile makes SS-750 a valuable reagent for research into antifungal therapies and resistance mechanisms.
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