3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester

Catalog No.: A27801
Anti-fungal Triterpene Saponin
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin targeting fungal cell membranes. Derived from the aerial parts of Clematis tangutica, this compound demonstrates significant antifungal activity against various strains, including P. avellaneum, C. glabrata, S. cerevisiae, and T. beigelii, with the most pronounced effect noted against S. cerevisiae. Its bioactivity makes it a valuable reagent for studies investigating antifungal mechanisms and potential therapeutic applications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin targeting fungal cell membranes. Derived from the aerial parts of Clematis tangutica, this compound demonstrates significant antifungal activity against various strains, including P. avellaneum, C. glabrata, S. cerevisiae, and T. beigelii, with the most pronounced effect noted against S. cerevisiae. Its bioactivity makes it a valuable reagent for studies investigating antifungal mechanisms and potential therapeutic applications.
Product Information
Catalog NumA27801
FormulaC41H66O12
Molecular Weight750.96
CAS Number639515-41-6
SMILESO[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1OC([C@]23[C@](CC(C)(CC3)C)([H])C4=CC[C@@]([C@@]5([C@@]([C@@](C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@H](CO6)O)O)O)CO)([H])CC7)C)([H])[C@]7(C)[C@@]4(CC2)C)=O
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