Antifungal agent 122

Catalog No.: A27757
Antifungal Agent
Antifungal Agent 122 is a potent broad-spectrum antifungal compound, primarily targeting fungal phase transition and biofilm formation. This agent inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11 µM and 4.53 µM, respectively. Notably, Antifungal Agent 122 demonstrates no cytotoxic effects, making it a valuable candidate for antifungal research applications.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAntifungal Agent 122 is a potent broad-spectrum antifungal compound, primarily targeting fungal phase transition and biofilm formation. This agent inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11 µM and 4.53 µM, respectively. Notably, Antifungal Agent 122 demonstrates no cytotoxic effects, making it a valuable candidate for antifungal research applications.
Product Information
Catalog NumA27757
FormulaC28H24F4N4O
Molecular Weight508.51
CAS Number3054212-80-2
SMILESFC1=CC=C([C@@]([C@H](N(C)CC2=CC=C(C#CC3=CC=C(F)C=C3F)C=C2)C)(O)CN4N=CN=C4)C(F)=C1
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