PF-1163A is an antifungal agent that functions as a C-4 sterol methyl oxidase inhibitor, effectively disrupting ergosterol synthesis with an IC50 of 12 ng/mL. This compound demonstrates notable antifungal activity, characterized by a minimum inhibitory concentration (MIC) of 12.5 µg/mL. PF-1163A is valuable for research applications focused on fungal infections and the mechanistic understanding of ergosterol biosynthesis.
PF-1163A is an antifungal agent that functions as a C-4 sterol methyl oxidase inhibitor, effectively disrupting ergosterol synthesis with an IC50 of 12 ng/mL. This compound demonstrates notable antifungal activity, characterized by a minimum inhibitory concentration (MIC) of 12.5 µg/mL. PF-1163A is valuable for research applications focused on fungal infections and the mechanistic understanding of ergosterol biosynthesis.
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