Antifungal agent 77 (Compound 13h) primarily targets fungal pathogens, exhibiting potent antifungal activity. At a concentration of 500 μg/mL, it demonstrates noteworthy insecticidal effects against various pests, including Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda, resulting in mortality rates of 30%, 25%, 40%, and 25%, respectively. Additionally, antifungal agent 77 exhibits toxicity in zebrafish embryos with a calculated LC50 of 2.43 μg/mL, highlighting its potential implications in ecological toxicology studies.
Antifungal agent 77 (Compound 13h) primarily targets fungal pathogens, exhibiting potent antifungal activity. At a concentration of 500 μg/mL, it demonstrates noteworthy insecticidal effects against various pests, including Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda, resulting in mortality rates of 30%, 25%, 40%, and 25%, respectively. Additionally, antifungal agent 77 exhibits toxicity in zebrafish embryos with a calculated LC50 of 2.43 μg/mL, highlighting its potential implications in ecological toxicology studies.
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