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Bioactive Alkaloid
Jatrorrhizine hydroxide is a bioactive alkaloid derived from Coptis chinensis, primarily known for its neuroprotective, antimicrobial, antiplasmodial, and antioxidant properties. It functions as a potent and orally active inhibitor of acetylcholinesterase (AChE) with an IC50 of 872 nM, exhibiting over 115-fold selectivity for butyrylcholinesterase (BuChE). Additionally, Jatrorrhizine hydroxide inhibits the uptake of serotonin (5-HT) and norepinephrine (NE) through the modulation of uptake-2 transporters, making it valuable for research in neuropharmacology and neurodegenerative disorders. -
GABAA/BZ Receptor Agonist
(E)-3,4,5-Trimethoxycinnamic acid is a potent GABAA/BZ receptor agonist characterized by multiple methoxy substitutions on its cinnamic acid structure. This compound demonstrates significant biological activity, including anticonvulsant and sedative effects, making it a valuable tool in research related to insomnia, headaches, and epilepsy. Additionally, (E)-3,4,5-Trimethoxycinnamic acid exhibits favorable binding affinity to the 5-HT2C and 5-HT1A receptors, with IC50 values of 2.5 and 7.6 μM, respectively, supporting its potential in neuropharmacological studies. -
GABAA Activator
Valerenic acid is a sesquiterpenoid that acts as a positive allosteric modulator of GABAA receptors, particularly enhancing the function of receptors containing the β3 subunit. Its anxiolytic properties are primarily mediated through this modulation. Additionally, Valerenic acid serves as a partial agonist at the 5-HT5a receptor and exhibits significant antioxidant activity, making it valuable in research related to anxiety disorders and oxidative stress. -
nAChR Agonist
Facinicline hydrochloride is a selective partial agonist of the nicotinic α7 acetylcholine receptor (nAChR), exhibiting a Ki of 6 nM. This compound has demonstrated potential in enhancing cognitive function and sensorimotor gating in rodent models, making it a valuable tool for research on cognitive disorders. Additionally, Facinicline hydrochloride shows high affinity as an antagonist at the 5-HT3 receptor, with a Ki of 1.2 nM, widening its applicability in neurological and psychiatric research. -
GABAB Receptor Positive allosteric modulator
ADX71441 is an orally active positive allosteric modulator of the GABAB receptor, capable of crossing the blood-brain barrier. With an EC50 of 96 nM, it enhances the effect of endogenous GABA, while also functionally inhibiting adenosine transporters and the 5-HT2B receptor. ADX71441 demonstrates a range of biological activities, including anxiolytic, analgesic, muscle relaxant, and hypothermic effects. Additionally, it reduces acute locomotor activity, decreases the voluntary intake of alcohol and saccharin, mitigates stress-induced neuronal activation, and exhibits anti-hyperalgesic properties, making it a valuable tool for research in neuropharmacology and related fields. -
mAChR Agonist
Isopteropodine is a positive modulator that selectively targets muscarinic acetylcholine receptors (mAChRs), exhibiting notable agonistic activity. It demonstrates an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-hydroxytryptamine (5-HT), highlighting its potential in neuroscience research related to cognitive function. Additionally, Isopteropodine displays antibacterial efficacy against Gram-positive bacteria, with minimum inhibitory concentrations (MICs) of 150 μg/mL for Staphylococcus aureus and 250 μg/mL for Bacillus subtilis, making it suitable for studies in antimicrobial activity and cognitive impairment. -
D1-like Dopamine-Receptor Antagonist
SKF-83566 hydrobromide is a selective antagonist of the D1-like dopamine receptors, exhibiting high blood-brain barrier permeability and oral bioavailability. This compound functions as a competitive inhibitor of the dopamine transporter (DAT), with an IC50 of 5.7 μM, and demonstrates a weaker antagonistic effect on the vascular 5-HT2 receptor (Ki=11 nM). Additionally, SKF-83566 selectively inhibits adenylyl cyclase 2 (AC2) over AC1 and AC5, making it a valuable tool for studying Parkinson's disease and nicotine dependence. -
Bioactive Alkaloid
Jatrorrhizine is a bioactive alkaloid derived from Coptis chinensis, known for its neuroprotective, antimicrobial, antiplasmodial, and antioxidant properties. This compound serves as a potent, orally active inhibitor of acetylcholinesterase (AChE) with an IC50 value of 872 nM, demonstrating over 115-fold selectivity for butyrylcholinesterase (BuChE). Additionally, Jatrorrhizine inhibits the uptake of serotonin (5-HT) and norepinephrine (NE) through the inhibition of uptake-2 transporters, making it a valuable reagent for neurological and pharmacological research. -
GABA Receptor Activator
2'-O-Methylisoliquiritigenin is a GABA receptor activator that enhances neurotransmitter activity across various pathways, including serotonin (5-HT), norepinephrine (NE), dopamine (DA), and GABA. Isolated from the Arachis species, this compound plays a significant role in modulating nervous system functions and offers valuable insights for research applications related to neurochemistry and pharmacology. Its selective influence on neurotransmitter pathways makes it a useful tool for studying neuropharmacological mechanisms. -
GABA transport system Inhibitor
Arecaidine is a potent inhibitor of the GABA transport system, impacting neurotransmitter uptake and signaling. It has been shown to inhibit the proliferation of oral mucosal fibroblasts, while also regulating cytokine secretion, specifically increasing IL-6, TGF-β, and TNF-α levels, and altering the expression of PPAR-γ and PCK1. Additionally, Arecaidine inhibits hPAT1-mediated proline uptake, making it a valuable tool for research into neurological diseases and related mechanisms. -
α7 nAChR Agonist
NS-6740 is a partial agonist of the α7 nicotinic acetylcholine receptor (α7 nAChR), exhibiting an IC50 of 3 nM. This compound functions as a potent modulator of the cholinergic anti-inflammatory pathway, influencing α7 signaling in an ion channel-independent manner, which ultimately reduces synaptic function. NS-6740 promotes the desensitized state of α7 nAChR and elicits substantial nAChR-mediated currents. It is effective in decreasing LPS-induced TNF-α release from microglia, making it a valuable tool for research into neuroinflammation and neuropathic pain mechanisms. -
α7 Nicotinic Acetylcholine Receptor Inhibitor
NS-6740 hydrochloride is a potent partial agonist of the α7 nicotinic acetylcholine receptor (α7 nAChR), exhibiting an IC50 of 3 nM. It functions as a modulator of the cholinergic anti-inflammatory pathway and alters α7 signaling in an ion channel-independent manner, which diminishes synaptic function and promotes receptor desensitization. NS-6740 hydrochloride has been shown to significantly reduce LPS-induced TNF-α release from microglia, making it a valuable tool in the study of neuroinflammation and neuropathic pain mechanisms. -
Dopamine Transporter Inhibitor
LH2-051 is a selective dopamine transporter (DAT) inhibitor with a Ki of 0.95 μM, effectively blocking DAT-mediated dopamine uptake with an IC50 of 3.0 μM. This compound also promotes the nuclear translocation of transcription factor EB (TFEB), enhancing lysosome biogenesis. LH2-051 has demonstrated potential in improving cognitive function in amyloid precursor protein (APP)/Presenilin 1 (PS1) mouse models, making it valuable for research focused on Alzheimer’s disease mechanisms and therapies. -
AAK1 Inhibitor
BMT-090605 hydrochloride is a selective inhibitor of the adapter protein-2 associated kinase 1 (AAK1), exhibiting a potent IC50 of 0.6 nM. This compound demonstrates significant antinociceptive activity, making it valuable for neuropathic pain research. Additionally, BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively, supporting its role in diverse biological investigations. -
AAK1 Inhibitor
BMT-090605 is a potent and selective inhibitor of adaptor protein-2 associated kinase 1 (AAK1), featuring an IC50 value of 0.6 nM. This compound exhibits significant antinociceptive activity and also demonstrates inhibitory effects on BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively. BMT-090605 is a valuable tool for research into mechanisms underlying neuropathic pain. -
AAK1/GAK Inhibitor
AAK1-IN-8 is a selective inhibitor of AAK1 and GAK, demonstrating effective inhibition with EC50 values of 50 nM and 190 nM, respectively. This compound significantly hinders the phosphorylation of the AP2-µ2 subunit at threonine 156, providing insight into clathrin-mediated endocytosis. AAK1-IN-8 is utilized in research applications focused on uncovering the roles of AAK1 and GAK in cellular processes and their implications in diseases related to endocytic pathways. -
P2Y11 Receptor Agonist
ATPγS tetralithium salt is a highly effective agonist of the P2Y11 receptor, playing a pivotal role in various cellular signaling pathways. This compound exhibits notable antioxidant properties and provides neuroprotection, enhancing its utility in neuroscience research. Additionally, ATPγS serves as a substrate for nucleotide hydrolysis and RNA unwinding activities mediated by the eukaryotic translation initiation factor eIF4A, making it valuable for studies related to translation and RNA biology. Its activity in ATP hydrolysis further supports its application in metabolic research. -
P2Y11 Receptor Agonist
ATP-γ-S tetrasodium is a potent agonist of the P2Y11 receptor, known for its antioxidant and neuroprotective properties. This compound serves as a substrate for nucleotide hydrolysis and facilitates RNA unwinding activities of the eukaryotic translation initiation factor eIF4A. Additionally, ATP-γ-S tetrasodium demonstrates significant activity in ATP hydrolysis, making it valuable for studies in cellular signaling and translational control. -
α7 nAChR Inhibitor
Conofurin-Delta is a potent inhibitor of the α7 nicotinic acetylcholine receptor (nAChR), exhibiting an IC50 of 177 nM. Additionally, it demonstrates inhibitory activity against the α9α10 nAChR with an IC50 of 98.1 nM. This compound is relevant for research applications in the study of SARS-CoV-2 infection and its impact on cholinergic signaling pathways. -
Anti-tumor Agent
Scoulerine hydrochloride is a multi-target inhibitor primarily acting as an anti-tumor agent. It disrupts the PI3K/Akt/mTOR signaling pathway and α1D-adrenergic receptors, leading to microtubule destabilization, cell cycle arrest, and apoptosis in cancer cells. This compound also inhibits mitochondrial dehydrogenase activity and demonstrates effects on GABA receptors and BACE1, suppressing tumor cell proliferation, migration, invasion, and stem cell-like properties. Additionally, Scoulerine hydrochloride exhibits pharmacological activities against Plasmodium falciparum, as well as antibacterial, antiemetic, and antitussive properties, while also influencing endoplasmic reticulum stress and mitochondrial function. It is particularly relevant in studies focused on leukemia, ovarian cancer, and colorectal cancer. -
Insecticide
Chlorphoxim is a highly efficient insecticide that acts by inhibiting acetylcholinesterase (AChE), leading to the disruption of neurotransmission in target pests. This compound also demonstrates the ability to inhibit superoxide dismutase (SOD) and catalase (CAT) activities in zebrafish embryos, thereby inducing oxidative stress through the activation of reactive oxygen species (ROS). Additionally, Chlorphoxim promotes apoptosis in zebrafish embryos by modulating the expression of pro-apoptotic and anti-apoptotic proteins such as Bax, Bcl2, and p53. Its neurotoxic and developmental effects make Chlorphoxim a key compound for agricultural research aimed at pest control. -
COX-1 Inhibitor
NCX 466 is a selective inhibitor of COX-1 and COX-2, demonstrating notable anti-inflammatory and analgesic properties. It functions as a nitric oxide (NO) donor, enhancing microcirculation while exerting antioxidant effects. NCX 466 effectively reduces levels of transforming growth factor-β (TGF-β) and oxidative stress markers, including thiobarbituric acid reactive substances (TBARS) and 8-hydroxy-2'-deoxyguanosine (8-OHdG). Furthermore, it mitigates leukocyte recruitment during inflammatory responses by decreasing myeloperoxidase (MPO) activity, contributing to the prevention of bleomycin-induced pulmonary fibrosis in murine models. -
P2Y14R Antagonist
HDL-16 is a highly potent antagonist of the P2Y14 receptor, exhibiting an IC50 of 0.3095 nM. This compound demonstrates significant biological activity by alleviating dextran sulfate sodium (DSS)-induced colitis, primarily through the inhibition of necroptosis in intestinal epithelial cells (IECs) and the preservation of mucosal barrier function. HDL-16 is valuable for research applications focused on inflammatory bowel diseases and related gastrointestinal disorders. -
Stable Isotope
Aldicarb sulfone-13C2,d3 is a labeled version of Aldicarb sulfone, incorporating both deuterium and carbon-13 isotopes. This compound acts as a cholinesterase inhibitor and is one of the primary metabolites of the carbamate pesticide Aldicarb, showcasing notable insecticidal activity. Aldicarb sulfone-13C2,d3 is valuable for chemical research applications, particularly in studies involving pesticide metabolism and its impact on cholinergic signaling pathways. -
Anti-colorectal Cancer Agent
ACS03 is a hybrid thiophene-acridine compound that targets colorectal cancer. It enhances the activity of key enzymes such as lactate dehydrogenase, glutathione S-transferase, and acetylcholinesterase, indicating its potential role in cellular metabolism. ACS03 exhibits selective anti-cancer effects, particularly against colon carcinoma, making it a valuable reagent for research applications in cancer biology and therapy development. Additionally, it demonstrates antileishmanial activity, broadening its relevance in infectious disease research. -
COX-2 Inhibitor
Hirsutanonol, a diarylheptanoid derived from the bark of Alnus hirsute var. sibirica, functions primarily as an inhibitor of cyclooxygenase-2 (COX-2). This compound exhibits significant anti-filarial activity, demonstrated by an IC50 value of 44.11 μg/mL against microfilariae. Hirsutanonol is valuable in research focused on inflammation reduction and parasitic disease interventions. -
COX-1 Inhibitor
Dihydroflavokawin B is a selective COX-1 inhibitor, exhibiting an IC50 of 1.22 μM, with moderate effects on COX-2 and 5-LOX. This compound demonstrates significant activity against the promastigote forms of Leishmania panamensis and Leishmania braziliensis, making it a valuable tool for leishmaniasis research. Additionally, Dihydroflavokawin B inhibits rabbit platelet aggregation induced by arachidonic acid, platelet-activating factor, and adenosine diphosphate, highlighting its potential for in vitro anti-inflammatory studies. -
Pesticide
(S)-Dinotefuran is a neonicotinoid pesticide that primarily targets the α8 subunit of nicotinic acetylcholine receptors (nAChRs) in honeybees, Apis mellifera. It exhibits higher toxicity compared to its R-enantiomer, R-dinotefuran, affecting the survival and behavior of these important pollinators. This compound is utilized in ecological and toxicological research to study the impact of pesticides on non-target species and to evaluate the risks associated with neonicotinoid exposure in agricultural settings. -
Parasite
Trimethacarb is a carbamate insecticide that primarily targets the nervous system of parasites. It inhibits key cholinesterase enzymes, leading to accumulation of acetylcholine and subsequent paralysis of target organisms. This compound is commonly utilized in research settings to study pest control methods and the biochemical mechanisms underlying insecticide action against various parasites. -
Stable Isotope
Pirimiphos-methyl-d6 is a deuterium-labeled derivative of Pirimiphos-methyl, an organophosphorus insecticide and acaricide that acts primarily through the inhibition of acetylcholinesterase (AChE) in target organisms. This compound is utilized in research for the development of analytical methods and for studying the biological activities of organophosphates. Its applications extend to the investigation of pest control mechanisms and the management of storage pests in agricultural grains. -
Stable Isotope
Pirimicarb-d6 is a deuterium-labeled derivative of Pirimicarb, serving as a stable isotope for analytical research. Pirimicarb functions as a selective carbamate insecticide, effectively inhibiting acetylcholinesterase (AChE) and displaying acaricidal properties. This reagent is widely applicable in studies related to insecticide action mechanisms and environmental fate assessments of carbamate pesticides in agricultural settings. -
Insecticide
Thiacloprid is an orally active neurotoxic insecticide that functions as an agonist of nicotinic acetylcholine receptors (nAChR). It has been shown to reduce cellular viability, deplete reduced glutathione, and elevate malondialdehyde (MDA) levels, leading to cytotoxicity and oxidative stress. While Thiacloprid exhibits lower acute toxicity to honeybees compared to some other insecticides, it adversely affects their learning, memory, immune function, and overall survival. Additionally, this compound disrupts intestinal microbiota, increasing the risk of premature colony collapse in bumblebees. Thiacloprid is utilized in the broad-spectrum control of agricultural pests across various crops, including potatoes, cabbages, fruits, vegetables, and nuts. -
Stable Isotope
Triazophos-d5 is a deuterium-labeled derivative of Triazophos, a non-systemic insecticide and acaricide that primarily targets acetylcholinesterase (AChE). By covalently and irreversibly binding to the acetylcholine binding site, Triazophos-d5 inhibits the hydrolysis of acetylcholine, resulting in increased neuromuscular activity and hyperexcitability in target pests. This compound is widely utilized in research to study insect resistance and as a tracer in ecological and environmental studies, particularly concerning its effects on various soil insects and mites affecting major crops such as cotton, rice, and soybeans. -
Ingredient In Insecticide And Acaricide Compositions
Primidophos is an organophosphorus compound that functions as an inhibitor of acetylcholinesterase. Its primary application lies in the formulation of insecticide and acaricide compositions, which target a variety of insect and mite pests. This compound is valuable in research focused on pest control and management strategies in agricultural and environmental settings. -
COX Inhibitor
Serratiopeptidase is a zinc-containing metalloprotease that primarily acts as a cyclooxygenase (COX) inhibitor. It effectively reduces the release of inflammatory mediators such as prostaglandins and interleukins, alleviating pain and swelling. In addition to its anti-inflammatory properties, Serratiopeptidase exhibits mucolytic, antibiofilm, and wound-healing activities. Its enzymatic action allows it to dissolve fibrin and blood clots, while also demonstrating potential anti-Alzheimer's effects by degrading amyloid fibrils. Furthermore, Serratiopeptidase shows cytotoxicity against colon cancer cells, making it a versatile reagent for research applications in inflammation and oncology. -
COX-2 Inhibitor
Thymohydroquinone is a selective inhibitor of cyclooxygenase-2 (COX-2) with noted anti-SARS-CoV-2 activity. It exhibits cytotoxic properties, antiproliferative effects, and the ability to suppress tumor growth in various cancer models. This compound is applicable in research focused on squamous cell carcinoma, fibrosarcoma, and the pathogenesis and treatment of COVID-19 caused by SARS-CoV-2. -
nAChR Aagonist
Simpinicline (OC-02) is a highly selective agonist of the nicotinic acetylcholine receptor (nAChR). This compound exhibits potent antiviral activity against SARS-CoV-2 variants in cell culture, with an IC50 value of 0.04 µM. Its unique selectivity and efficacy make it a valuable tool for research in virology and neuropharmacology. -
Natural Compound
Lucidadiol is a natural compound derived from Ganoderma lucidum, functioning as an acetylcholinesterase inhibitor with an IC50 value of 31 μM. This compound also demonstrates antiviral activity against influenza virus type A and herpes simplex virus type 1 (HSV-1). Lucidadiol is valuable for research applications exploring neuroprotective mechanisms and viral infection inhibition. -
Anthelmintic Agent/Immunoregulatory Agent
Levamisole is an anthelmintic agent recognized for its immunoregulatory properties. This compound functions as a positive allosteric modulator of the α3β2 (EC50 = 300 μM) and α3β4 (EC50 = 100 μM) subtypes of nicotinic acetylcholine receptors (nAChRs), enhancing receptor activity. It is orally active and is commonly used in research applications related to parasitic infections and immune response modulation. -
AChE Inhibitor
Coumaran, also known as 2,3-Dihydrobenzofuran, is an inhibitor of acetylcholinesterase (AChE) and exhibits notable antileishmanial activity. Its mechanisms include the activation of macrophages, contributing to its antiparasitic effects and immunomodulatory properties. Coumaran is also applicable in the field of biopesticides, providing a potential tool for agricultural and biological research. -
Nicotinic acetylcholine receptors Inhibitor
Dinotefuran is a competitive inhibitor targeting insect nicotinic acetylcholine receptors (nAChRs). This compound effectively disrupts neural signaling in insects, leading to dysfunction. With an IC50 of 890 nM for [3H]epibatidine and 36.1 μM for [3H]α-bungarotoxin in American cockroach neural membranes, Dinotefuran demonstrates significant knockdown (KD50=0.351 nmol/g) and lethal activity (LD50=0.173 nmol/g) against German cockroach. Its primary applications include agricultural pest control, specifically targeting piercing-sucking and chewing insects like aphids and planthoppers, and it also serves as a tool for studying environmental toxicological impacts such as oxidative stress and reproductive neurotoxicity in earthworms. -
Glucosylceramide Synthase Inhibitor
DL-threo-PDMP hydrochloride is a competitive inhibitor of glucosylceramide synthase (GCS), demonstrating significant potential in antimalarial research. This compound effectively inhibits GCS activity, leading to restored sensitivity to cisplatin in cisplatin-resistant testicular germ cell tumor cells. Additionally, DL-threo-PDMP hydrochloride has been shown to impede the growth of ring-stage Plasmodium falciparum parasites, making it a valuable tool for studying malaria and its treatment. -
ChE Inhibitor
N-p-trans-Coumaroyltyramine is a natural phenolic amide compound that acts as an inhibitor of acetylcholinesterase (AChE) with an IC50 of 122 μM and α-glucosidase with an IC50 of 2.7 μM. It demonstrates significant anti-trypanosomal activity, exhibiting an IC50 of 13.3 µM against Trypanosoma brucei rhodesiense. This compound is valuable for research into neurodegenerative diseases such as Alzheimer's disease, as well as for studies focusing on trypanosomiasis. -
Parasite Inhibitor
Diazinon is an irreversible acetylcholinesterase (AChE) inhibitor with primary applications in pest control as an insecticide. By inhibiting AChE, Diazinon leads to the accumulation of acetylcholine, resulting in overstimulation of acetylcholine receptors and disruption of nervous system function. Additionally, Diazinon generates reactive oxygen species (ROS), contributing to oxidative stress across various biological tissues. This compound is predominantly utilized in agricultural settings but may also hold implications for human and animal health research. -
AChE Inhibitor
Carbosulfan is an orally active acetylcholinesterase (AChE) inhibitor that hydrolyzes to carbofuran, leading to significant insecticidal properties. This compound demonstrates broad-spectrum insecticidal activity while inducing oxidative stress through increases in lipid peroxidation and impairment of antioxidant defenses. Carbosulfan is associated with reproductive toxicity in male rats and developmental disorders in offspring, making it a relevant subject in studies focused on reproductive toxicity and environmental risk assessment. Its persistence in aquatic environments raises concerns regarding potential hazards to non-target organisms. -
Parasite Inhibitor
8-Deoxygartanin, a prenylated xanthone derived from Garcinia mangostana, serves as a selective inhibitor of butyrylcholinesterase (BChE). This compound demonstrates significant antiplasmodial activity, with an IC50 value of 11.8 μM against the W2 strain of Plasmodium falciparum. Additionally, 8-Deoxygartanin inhibits NF-κB (p65) activation, displaying an IC50 of 11.3 μM, making it a valuable reagent for research in parasitic infections and inflammation pathways. -
Organophosphorus Insecticide
Pirimiphos-methyl is an organophosphorus insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor in target organisms. This compound is effective in the prevention and control of a variety of pests, including beetles, snout beetles, moths, and Ephestia cautella, particularly during the storage of agricultural grains. Its efficacy in disrupting neural signaling makes it valuable for research into pest management strategies and environmental impact studies in agricultural settings. -
nAChR Antagonist
Derquantel is a spirocyclic anthelmintic that functions as a competitive antagonist of nicotinic acetylcholine receptors (nAChRs). It inhibits acetylcholine-induced depolarization with an IC50 of 0.22 μM, leading to flaccid paralysis of nematode somatic muscles. This mechanism effectively dislodges parasites from the host gastrointestinal tract, making Derquantel a valuable tool in research related to Haemonchus contortus and Ascaris suum infections. -
Cholinesterase (ChE) Inhibitor
Fenchlorphos is an organophosphate compound that acts as a potent inhibitor of acetylcholinesterase (AChE), an important enzyme in cholinergic signaling. By disrupting AChE activity, Fenchlorphos leads to the accumulation of acetylcholine, resulting in increased cholinergic neurotransmission. Additionally, this compound has been shown to induce mitochondrial dysfunction, making it a valuable tool for research on neurobiology and toxicology. Its applications include studies on the mechanisms of insecticide action and investigations into the impacts of cholinergic inhibition on cellular metabolism. -
Carbamate Insecticide
Pirimicarb is a selective carbamate insecticide that functions as an acetylcholinesterase (AChE) inhibitor, making it effective against a variety of pests. It exhibits rapid action and is suitable for use on a broad spectrum of crops, including cereals, sugar beet, potatoes, fruits, and vegetables. Pirimicarb's efficacy extends to its acaricidal properties, supporting extensive research in agricultural pest control mechanisms.

