Fig. 1 · Structure
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Levamisole
Anthelmintic Agent/Immunoregulatory Agent
Levamisole is an anthelmintic agent recognized for its immunoregulatory properties. This compound functions as a positive allosteric modulator of the α3β2 (EC50 = 300 μM) and α3β4 (EC50 = 100 μM) subtypes of nicotinic acetylcholine receptors (nAChRs), enhancing receptor activity. It is orally active and is commonly used in research applications related to parasitic infections and immune response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 14769-73-4 |
| Applications | Anthelmintic Agent/Immunoregulatory Agent |
| Formula | C11H12N2S |
| Molecular Weight | 204.30 |
| Synonyms | (-)-Tetramisole |
| SMILES | C12=N[C@@H](C3=CC=CC=C3)CN1CCS2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.