Fig. 1 · Structure
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Isopteropodine
Cat. No.
A45983
CAS
5171-37-9
mAChR Agonist
Isopteropodine is a positive modulator that selectively targets muscarinic acetylcholine receptors (mAChRs), exhibiting notable agonistic activity. It demonstrates an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-hydroxytryptamine (5-HT), highlighting its potential in neuroscience research related to cognitive function. Additionally, Isopteropodine displays antibacterial efficacy against Gram-positive bacteria, with minimum inhibitory concentrations (MICs) of 150 μg/mL for Staphylococcus aureus and 250 μg/mL for Bacillus subtilis, making it suitable for studies in antimicrobial activity and cognitive impairment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 5171-37-9 |
| Applications | mAChR Agonist |
| Formula | C21H24N2O4 |
| Molecular Weight | 368.43 |
| SMILES | O=C(C1=CO[C@@H](C)[C@]([C@]1([H])C[C@]23[H])([H])CN2CC[C@]43C(NC5=C4C=CC=C5)=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.