BMT-090605 hydrochloride is a selective inhibitor of the adapter protein-2 associated kinase 1 (AAK1), exhibiting a potent IC50 of 0.6 nM. This compound demonstrates significant antinociceptive activity, making it valuable for neuropathic pain research. Additionally, BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively, supporting its role in diverse biological investigations.
BMT-090605 hydrochloride is a selective inhibitor of the adapter protein-2 associated kinase 1 (AAK1), exhibiting a potent IC50 of 0.6 nM. This compound demonstrates significant antinociceptive activity, making it valuable for neuropathic pain research. Additionally, BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively, supporting its role in diverse biological investigations.
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