SPL-B

Catalog No.: A16085

TACC3 inhibitor

SPL-B

SPL-B Chemical Structure

CAS NO. 1465248-60-5

SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $140.00

Special Price $112.00

10 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $980.00

Special Price $784.00

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Biological Activity

SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22 mL 110.02 mL 220.03 mL
0.5 mM 4.4 mL 22 mL 44.01 mL
1 mM 2.2 mL 11 mL 22 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16085
Actions Inhibitor
CAS No. 1465248-60-5
Formula C27H22N2O5
M. Wt 454.48
Purity >98%
Synonyms Spindlactone B
SMILES CCN(CC1=CC=NC=C1)CC2=C(C=CC3=C2OC(=O)C=C3C4=CC5=CC=CC=C5OC4=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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