Catalog No.
Product Name
Application
Product Information
Citations
- Bisoctrizole is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays. Also a hybrid UV absorber, reflecting and scattering UV.
- (Z)-2-decenoic acid is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a disp .
- 9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.
- Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1), an antioxidant dietary supplement.
- Deferasirox Fe3+ chelate is a rationally-designed oral iron chelator; its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.
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DA neurotoxin
MPTP hydrochloride induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats.- Sai Teja Meka, .et al. , Eur J Pharmacol, 2023, Nov 15:959:176067 PMID: 37751833
- Philemon Dauda Shallie, .et al. , Annual Research & Review in Biology, 2017, 13(5): 1-11
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SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. -
SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.- Gia-Buu Tran, .et al. , Cancer Res, 2023, Apr 14;CAN-22-3450 PMID: 37057874
- Weber RA, .et al. , Mol Cell, 2020, Feb 6;77(3):645-655 PMID: 31983508
- Garcia-Bermudez J, .et al. , Nature, 2019, Feb 13 PMID: 30760928
- Pafuramidine is an orally bioavailable prodrug of furamidine, which has clinical activity against Pneumocystis pneumonia.
- Retinyl glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.
- sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types.
- Sodium formononetin-3'-sulfonate is a water-sol. derivate of formononetin.
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MyD88 dimerization Inhibitor
ST 2825 is a MyD88 pharmacologic inhibitor.- Bernard Kan, .et al. , Nat Commun, 2018, 9: 4822 PMID: 30446641
- Shira Dishon, .et al. , Sci Rep, 2018, 8: 9476 PMID: 29930295
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Morphine-like substance
Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides. -
TPA/PMA inhibitor
Cyclosporin H is a TPA/PMA inhibitor and a selective inhibitor of formyl peptide receptors (Ki = 0.1 uM).- Jean-Philippe Auger, .et al. , Nature, 2024, May;629(8010):184-192 PMID: 38600378
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Cell adhesion inhibitor
K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1beta or TNF-alpha. -
DNA repair inhibitor
KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma. -
mitochondria-targeted antioxidant
SKQ1 is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. SKQ1 showed activities (1) to prevent amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices.- Massimo Costanza, .et al. , PNAS, 2019, 2019 PMID: 30988194
- Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases.
- CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = <0.5 μM in a cell-free assay) and inhibits LPS-induced IL-6 secretion in THP-1 cells (IC50 = <0.5 μM).
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luminescent enzyme substrate
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques. - Brevianamide F belongs to a class of naturally occurring 2,5-diketopiperazines.
