2,3-Dehydro-3,4-dihydro ivermectin is an impurity of ivermectin, primarily exhibiting anthelmintic properties. It demonstrates anti-parasitic activity against Leishmania amazonensis promastigotes and amastigotes, with IC50 values of 13.8 µM and 3.6 µM, respectively. Importantly, this compound does not induce cytotoxicity in macrophages, with an IC50 of 65.5 µM, making it suitable for studies in parasitology and drug development research.
2,3-Dehydro-3,4-dihydro ivermectin is an impurity of ivermectin, primarily exhibiting anthelmintic properties. It demonstrates anti-parasitic activity against Leishmania amazonensis promastigotes and amastigotes, with IC50 values of 13.8 µM and 3.6 µM, respectively. Importantly, this compound does not induce cytotoxicity in macrophages, with an IC50 of 65.5 µM, making it suitable for studies in parasitology and drug development research.
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