Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes.
Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes.
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