Catalog No.
Product Name
Application
Product Information
Citations
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Antimicrobial Peptide
Polistes mastoparan is an antimicrobial peptide that exerts its effect by increasing potassium ion (K+) efflux in Staphylococcus aureus, leading to impaired cell viability. With an effective concentration (EC50) of 5 μM, it serves as a valuable tool for research focused on bacterial cell physiology and antimicrobial mechanisms. This compound is particularly relevant for studies investigating the development of new antimicrobial strategies. -
Bioactive Peptide
BMAP-18 is a bioactive peptide derived from the antimicrobial peptide BMAP-27, belonging to the Cathelicidin family. It exhibits potent bactericidal activity against Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-18 demonstrates improved cell selectivity compared to its parental form, showing reduced hemolytic activity while maintaining effective antimicrobial properties. This peptide is suitable for research applications focused on antimicrobial mechanisms and therapeutic strategies against bacterial infections. -
Antibacterial Peptide
Astacidin 1 is an antibacterial peptide that exerts its effects through targeted activity against a wide range of bacterial pathogens. Produced via proteolytic cleavage from hemocyanin under acidic conditions, Astacidin 1 demonstrates broad-spectrum antibacterial activity, effectively inhibiting the growth of both Gram-positive and Gram-negative bacteria. This peptide serves as a valuable tool for antimicrobial research and the development of new therapeutic strategies. -
Antimicrobial Peptide, stable
K11 is a stable antimicrobial peptide that exhibits significant activity against multidrug-resistant and extensively drug-resistant K. pneumoniae isolates, demonstrating a minimum inhibitory concentration (MIC) range of 8-512 μg/mL. This peptide not only inhibits bacterial biofilm formation but also displays synergistic effects when combined with various antibiotics, including chloramphenicol, meropenem, and rifampicin, enhancing the efficacy against drug-resistant strains. K11 maintains high thermal stability and demonstrates effective function across a broad pH range, making it a valuable tool for antimicrobial research and therapeutic applications. -
Peptide
CAP 37 (20-44) is a peptide derived from amino acid residues 20 to 44 of CAP37, a cationic antimicrobial protein. This peptide exhibits significant antimicrobial activity, making it a valuable tool for studying innate immune responses. CAP 37 (20-44) is applicable in research focused on antimicrobial mechanisms and the development of host defense peptides. -
Antimicrobial Peptide
Defensin NP-3A is an antimicrobial peptide derived from human granulocytes, known for its potent cytotoxic activity against various pathogens. It also exhibits anti-adrenocorticotropic hormone (ACTH) effects. This peptide is valuable for research applications focused on innate immunity, antimicrobial activity, and the modulation of endocrine responses. -
Immunogen Peptide
Tetanus toxin peptide is an immunogen peptide derived from the toxin of Clostridium tetani. This peptide has demonstrated utility in inducing diabetes in murine models, making it a valuable tool for studying the mechanisms of type 1 diabetes. Its application in research facilitates a deeper understanding of autoimmune responses and potential therapeutic intervention strategies. -
Polypeptide
LL-37 FKR is a C-terminal fragment of the antimicrobial peptide LL-37, targeting bacterial membranes. This polypeptide exhibits significant antibacterial activity, making it an essential tool in studies focused on innate immunity and antimicrobial resistance. Its role in modulating immune responses also positions it for applications in inflammation and infection research. -
Antimicrobial Peptide
Retrocyclin-3 is an antimicrobial peptide that targets viral infections, specifically human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). It exhibits potent antiviral activity, making it a valuable tool for research into antiviral therapies and the mechanisms of viral resistance. Its unique structure and function offer insights into the development of novel antimicrobial strategies. -
Antimicrobial Peptide
Palicourein is a 37 amino acid cyclic polypeptide that functions as an antimicrobial peptide. It exhibits potent inhibitory activity against the cytopathic effects of HIV-1RF infection in CEM-SS cells, with an EC50 value of 0.1 μM and an IC50 value of 1.5 μM. This compound is valuable for research applications focused on antiviral activity and the study of peptide-based therapeutics. -
Antimicrobial Peptide
Onc112 is a proline-rich antimicrobial peptide that primarily targets Gram-negative bacteria. It exerts its biological activity by inhibiting translation, specifically by blocking and destabilizing the initiation complex. This mechanism makes Onc112 a valuable tool for research applications focusing on bacterial resistance and the development of novel antimicrobial strategies. -
Antimicrobial Peptide
Mel4 is an antimicrobial peptide that exhibits broad-spectrum antimicrobial activity. It effectively neutralizes bacterial lipopolysaccharide in a dose-dependent manner, making it a valuable tool for investigating the mechanisms underlying bacterial infections. Mel4 can be utilized in research focused on the prevention and treatment of bacterial infectious diseases, including ocular infections. -
Antimicrobial Peptide
Hp1404 is a novel cationic antimicrobial peptide with specific inhibitory activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This compound exhibits significant antimicrobial activity while maintaining low toxicity and a reduced likelihood of inducing drug resistance. Hp1404 serves as a valuable research tool in the investigation of antimicrobial agents and their mechanisms of action. -
Bioactive Peptide
Lactoferricin H, a bioactive peptide derived from human lactotransferrin (amino acids 37-61), exhibits significant antimicrobial properties. This peptide plays a crucial role in innate immunity, demonstrating the ability to combat a range of microorganisms. Its applications in research include studying host defense mechanisms and developing novel antimicrobial therapies. -
Antimicrobial Peptide
BMAP 28 (bovine) is an antimicrobial peptide known for its potent antibacterial properties. It targets both gram-positive and gram-negative bacteria by disrupting cell membrane integrity, leading to increased permeability and leakage of intracellular contents. Additionally, BMAP 28 demonstrates cytotoxic effects on cancer cells and activated human lymphocytes, inducing apoptosis via depolarization of mitochondrial membrane potential. This peptide is valuable for research applications focused on antimicrobial resistance and cancer therapeutics. -
Antimicrobial Peptide
Maximin S4 is an antimicrobial peptide derived from the skin secretions of the toad Bombina maxima. This peptide exhibits significant antibacterial activity, particularly against mycoplasma species. It serves as a valuable reagent for research into peptide-based antimicrobial strategies and the exploration of innate immune mechanisms. -
Antimicrobial Peptide
Pexiganan acetate is an antimicrobial peptide that disrupts the cell membrane permeability of bacterial cells, leading to their death. This compound exhibits broad-spectrum activity against both Gram-positive and Gram-negative aerobic bacteria, achieving up to 99% inhibition. Pexiganan acetate is primarily utilized in research applications focusing on infections, including those associated with diabetic foot ulcers. -
Antimicrobial Peptide
Cyclic L27-11 is a cyclic peptide antibiotic primarily targeting bacterial outer membrane protein LptD. It exhibits potent nanomolar antibacterial activity against Pseudomonas species, particularly Pseudomonas aeruginosa. By disrupting the transport of lipopolysaccharide (LPS), Cyclic L27-11 leads to the accumulation of membrane-like substances within bacterial cells, ultimately impacting bacterial viability. This compound serves as a valuable tool in the development of new antibacterial agents. -
Antimicrobial Peptide
Dermaseptin-B4 is an antimicrobial peptide that primarily targets microbial cell membranes. It exhibits potent antibacterial, antifungal, and antiviral activities, making it a valuable tool in the study of host defense mechanisms and the development of novel therapeutic agents. Its broad-spectrum activity is especially relevant for research in infectious diseases and antimicrobial resistance. -
Antimicrobial Peptide
Pardaxin P 4 is an antimicrobial peptide that targets and interacts with biomembranes. It exhibits a unique mechanism of inducing cytotoxicity and pore formation by disrupting phospholipid bilayers of varying compositions. This peptide is valuable for research applications focused on developing antimicrobial drugs and exploring membrane-disruptive mechanisms in microbial defense. -
Antimicrobial Peptide
Myxinidin is an antimicrobial peptide that targets bacterial and fungal biofilms. It demonstrates significant activity against biofilms formed by Pseudomonas aeruginosa and various Candida species, effectively inhibiting and eradicating these resilient microbial colonies. Myxinidin is suitable for research applications focusing on infection control and biofilm-related studies. -
Antimicrobial Peptides
Hispidalin is a novel antimicrobial peptide that exhibits broad-spectrum antibacterial and antifungal activity by disrupting microbial membrane integrity. Its mechanism of action makes it a valuable candidate for applications in antibacterial therapeutics and food preservation. Research with Hispidalin may further elucidate its potential in combating resistant strains of pathogens. -
pH-responsive And Self-assembling Peptide
IKFQFHFD is a pH-responsive self-assembling peptide that exhibits biocompatibility at neutral pH. When exposed to acidic conditions, it transforms into an antimicrobial peptide-like structure, demonstrating significant potential in targeting biofilm infections. This peptide can be applied in research focused on chronic wound management, including venous ulcers, diabetic ulcers, and pressure ulcers, offering insights into novel therapeutic strategies. -
Bioactive Peptide
Retro-indolicidin is a bioactive peptide that functions as an antimicrobial agent. This synthetic reverse peptide, derived from indolicidin, consists of 13 amino acid residues and retains significant antimicrobial and protease inhibitory activities in vitro. Retro-indolicidin is applicable in research focused on antimicrobial properties, host defense mechanisms, and potential therapeutic strategies against microbial infections. -
Oligopeptide
Cyclamide is an oligopeptide derived from cyanobacterial algae strains, known for its potential therapeutic effects. It has been studied for its impact on glucose metabolism and insulin regulation, making it relevant for diabetes mellitus research. Cyclamide serves as a valuable tool in the exploration of metabolic disorders and may aid in the development of novel treatments for diabetes. -
Antimicrobial Peptide
Temporin SHF is a broad-spectrum antimicrobial peptide that targets microbial membranes. This peptide effectively combats both Gram-positive and Gram-negative bacteria as well as yeasts, while exhibiting a lack of hemolytic activity. Its mechanism involves disrupting acyl chain stacking within anionic lipid bilayers, resulting in membrane disintegration. Temporin SHF demonstrates significant potential for developing new antimicrobial therapies. -
Antibacterial Peptide
Acetyl-Adhesin (1025-1044) amide is a 20-peptide fragment derived from the cell surface adhesin of Streptococcus pyogenes, functioning as an antibacterial peptide. This compound specifically inhibits the interaction between adhesin and salivary receptors, thereby preventing the recolonization of Streptococcus pyogenes. Its potential applications include studies in microbial pathogenesis and the development of novel antimicrobial strategies. -
Immunomodulatory Peptide
IDR-HH2 is an immunomodulatory peptide targeting the host cytokine and chemokine milieu. It facilitates the adhesion of monocytes and THP-1 cells to fibronectin, enhancing immune cell recruitment. Additionally, IDR-HH2 exhibits antibacterial properties, demonstrating inhibitory effects against Pseudomonas aeruginosa and Staphylococcus aureus, with minimum inhibitory concentration (MIC) values of 75 µg/mL and 38 µg/mL, respectively. This peptide is valuable for research in immunology and antimicrobial studies. -
Antimicrobial Peptide
C16G2 is a specific targeted antimicrobial peptide (STAMP) that selectively targets the cariogenic oral pathogen Streptococcus mutans. It disrupts the bacterial cell membrane, resulting in leakage of small molecules and loss of membrane potential, ultimately leading to bacterial cell death. C16G2 demonstrates enhanced selectivity and efficacy against Streptococcus mutans compared to broad-spectrum antimicrobial peptides, making it a valuable tool for research in oral microbiology and infection control. -
Antimicrobial Peptide
Pantinin-2 is an antimicrobial peptide derived from the emperors scorpion (Pandinus imperator), demonstrating potent activity against Gram-positive bacteria. It also exhibits antifungal activity against Candida tropicalis, while displaying low hemolytic activity against human erythrocytes. This peptide serves as a valuable tool in the development of novel antimicrobial agents targeting drug-resistant pathogens. -
Antimicrobial Peptide
MCF is an antimicrobial peptide derived from bee venom, targeting bacterial membranes. It exhibits potent antimicrobial activity against Escherichia coli W 160-37, Staphylococcus aureus 8530, and Bacillus subtilis, with minimum inhibitory concentration (MIC) values ranging from 15-45 μg/ml. MCF is suitable for research applications in microbiology and the development of novel antimicrobial agents. -
Antimicrobial Peptide
Bombolitin III is an antimicrobial peptide that originates from bumblebee venom. It exhibits significant activity by lysing erythrocytes and liposomes, demonstrating a potential mechanism for disrupting microbial cell membranes. This compound is primarily utilized in research applications focused on antimicrobial activity and the study of peptide interactions with biological membranes. -
Antimicrobial Peptide
Brevicidine is an antimicrobial peptide that demonstrates selective bactericidal activity against Gram-negative pathogens. It functions by binding to lipopolysaccharide (LPS) on the bacterial cell membrane, leading to pore formation and subsequent disruption of bacterial morphology. This results in the dissipation of the proton motive force, outer membrane damage, inhibition of ATP biosynthesis, and accumulation of reactive oxygen species within bacterial cells. Additionally, Brevicidine acts as a sensitizer, exhibiting synergistic effects when combined with various conventional antibiotics, making it valuable for research in antimicrobial resistance and antibiotic enhancement studies. -
Dual-target Anti-inflammatory Peptide
Pegtarazimod is a dual-target anti-inflammatory peptide that regulates both the complement system and neutrophil-associated inflammatory pathways. It demonstrates significant biological activity by reducing reactive oxygen species (ROS) production and lowering neutrophil elastase levels in vivo, thereby mitigating inflammatory responses. Pegtarazimod has shown improved survival rates in multiple in vivo models of acute graft-versus-host disease (aGVHD) and exhibits efficacy against herpes simplex virus type 1 infections by inhibiting the activation of the C1 complex. This reagent is applicable in research focused on aGVHD, acute pulmonary diseases, and skin infections caused by herpes simplex virus type 1. -
Antibacterial Peptide
KSL-W is a multifunctional antibacterial peptide primarily targeting immune regulation. It exhibits significant chemotactic effects on neutrophils and promotes F-actin polymerization through the Gαi protein signaling pathway. Additionally, KSL-W effectively inhibits the production of reactive oxygen species (ROS) in neutrophils. This peptide is valuable for research focused on infection control and the regulation of inflammatory processes. -
Bioactive Peptide
PSTi8 is a bioactive peptide that functions as a specific inhibitor of pancreastatin, a neuropeptide involved in glucose and lipid metabolism. This compound exhibits potential in modulating pancreatic function and addressing metabolic disorders. Its applications extend to basic research in endocrinology and metabolic disease studies, offering insights into peptide signaling pathways and their physiological implications. -
Peptide Mimic
PKHB1 is a thrombospondin-1 peptide mimic that exerts antitumor effects primarily through mitochondrial dysfunction. It promotes the production of reactive oxygen species (ROS), triggers intracellular calcium accumulation, and activates calcium-dependent apoptotic pathways in breast cancer cells. Additionally, PKHB1 facilitates immune system activation by inducing immunogenic cell death, making it a valuable tool for research into cancer therapeutics and immunology. -
Peptide
α-Neoendorphin (porcine) is a peptide that acts on the skin's cellular mechanisms to mitigate UVB-induced photoaging. It activates the mTOR-Beclin-1 pathway to enhance autophagy, decreases reactive oxygen species (ROS) production, inhibits the MAPK signaling pathway and matrix metalloproteinase (MMP) activity, while promoting synthesis of type I procollagen. This compound demonstrates significant anti-aging and anti-wrinkle properties in skin cell models, making it valuable for research focused on skin photoaging and age-related dermatological studies. -
MLCK Inhibitor
MLCK Inhibitor Peptide 18 is a selective inhibitor of myosin light chain kinase (MLCK) with an IC50 of 50 nM. This peptide demonstrates significant inhibition of MLCK activity while exhibiting minimal effects on Ca2+/calmodulin-dependent protein kinase II, requiring concentrations approximately 4000-fold higher for inhibition. This specificity makes it valuable for studying MLCK-related signaling pathways and cellular processes involving muscle contraction and cellular motility. -
CaMKII Inhibitor
Autocamtide-2-related inhibitory peptide, myristoylated is a potent and selective inhibitor of CaMKII, exhibiting an IC50 of 40 nM. This peptide is used in research applications to investigate the regulatory mechanisms of calcium-dependent signaling pathways. Its myristoylation enhances its membrane permeability, facilitating in vivo studies of CaMKII activity and function in various cellular contexts. -
Histone H3 Peptide
Histone H3 (1-35) is a peptide comprising the first 35 amino acids of the histone H3 protein, which plays a pivotal role in chromatin packaging and organization in eukaryotic cells. This peptide is essential in studies of epigenetic regulation and gene expression, serving as a tool for investigating histone modification and interaction dynamics. It is widely used in research applications that explore chromatin structure, transcriptional regulation, and the effects of histone modifications on cellular processes. -
Synthetic Peptide Nucleic Acid
Fmoc-PNA-G(Boc)-OH is a synthetic peptide nucleic acid (PNA) featuring Fmoc and Boc protecting groups, which are designed to facilitate the synthesis of complementary DNA or RNA sequences. This reagent exhibits strong binding affinity and specificity, making it an essential tool for applications in gene modification, diagnostics, and molecular biology research. Its robust characteristics enhance its utility across various experimental setups, allowing for precise targeting and manipulation of nucleic acid interactions. -
Peptide
Preptin (rat) is an osteogenic peptide derived from the pancreatic beta-cell, specifically representing the Asp69-Leu102 segment of pro-IGF-II. This peptide plays a significant role in bone metabolism and has been shown to stimulate osteoblast differentiation and activity. Preptin is utilized in research applications aimed at understanding bone development, cellular signaling pathways, and the potential therapeutic effects in metabolic bone disorders. -
Epidermal Cell Proliferation Inhibitor
Epidermal mitosis inhibiting pentapeptide primarily functions as an inhibitor of epidermal cell proliferation. This pentapeptide significantly reduces the DNA synthesis and mitotic rates of epidermal keratinocytes, making it a valuable tool in the study of skin cell dynamics. While it may moderately increase the incidence of skin tumors in cancer models, it also demonstrates a heightened capacity to promote regression of established tumors. Additionally, this compound is hydrolyzed by angiotensin-converting enzyme (ACE), further broadening its utility in cancer research applications. -
Holliday Linker Inhibitory Peptide
KWWCRW is a Holliday linker inhibitory peptide that targets homologous recombination repair (HDR) in DNA repair mechanisms. By binding to the reactive Holliday linker intermediate, KWWCRW prevents its degradation, thereby inhibiting HDR and site-specific recombination by bacteriophage in vitro. This peptide is valuable in cancer research, particularly in studying DNA repair pathways and potential therapeutic interventions. -
Peptide Nucleic Acid
Fmoc-PNA-Abasic(Boc)-OH is a synthetic peptide nucleic acid that features Fmoc and Boc protecting groups. This compound serves as a versatile tool in molecular biology research, particularly in the study of nucleic acid interactions and the design of antisense oligonucleotides. Its modified structure enhances stability while enabling specific applications in gene regulation and molecular diagnostics. -
Bioactive Peptide
Influenza virus PA (46-54) is a bioactive peptide derived from the HLA-A*0201 restricted epitope of the influenza virus RNA polymerase subunit. This peptide is instrumental in research related to influenza virus immunology and vaccine development. It serves as a valuable tool for studying T cell responses and evaluating immune evasion mechanisms related to the influenza virus. -
Nucleolin Ligand
F3 peptide is a specific ligand for nucleolin, a protein commonly expressed on the surface of cancer cells, neovasculature, and endothelial cells. This peptide is derived from the human high mobility group protein 2 (HMGB2) and enhances the delivery of macromolecular drugs and nanoparticles. Its ability to selectively bind to nucleolin makes F3 peptide a valuable tool in cancer research and targeted therapeutic development. -
vasoactive peptide
Vasoactive intestinal contractor is a vasoactive peptide that functions as a potent stimulator of intracellular calcium concentration. It activates calcium signaling pathways, leading to a rapid increase in Ca2+ levels in cells such as fura-2-overexpressed Swiss 3T3 fibroblasts. This compound is utilized in research related to cellular signaling, smooth muscle contraction, and studies on the endothelin family of peptides. -
Melanin Synthesis Inducer
Tetrapeptide, a peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), functions as a melanin synthesis inducer. This compound not only promotes melanin production but also mitigates DNA damage by decreasing the formation of reactive oxidative species and enhancing the repair mechanisms for DNA photoproducts. It is valuable in research applications focused on skin pigmentation and photoprotection.
