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Neuropeptide Y Y1 receptor antagonist 1

Catalog No.: A43885
Neuropeptide Y Y1 Receptor Antagonist
Neuropeptide Y Y1 Receptor Antagonist 1 is a potent antagonist of the neuropeptide Y Y1 receptor (Y1R), exhibiting a Ki value of 0.19 nM. This compound serves as a valuable tool in neurobiology research, facilitating the investigation of neuropeptide signaling pathways and their roles in various physiological processes. Its applications include studying the effects of Y1R modulation on neuroendocrine responses, food intake, and anxiety-related behaviors.
Neuropeptide Y Y1 receptor antagonist 1 2773476-40-5 Neuropeptide Y Y1 Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNeuropeptide Y Y1 Receptor Antagonist 1 is a potent antagonist of the neuropeptide Y Y1 receptor (Y1R), exhibiting a Ki value of 0.19 nM. This compound serves as a valuable tool in neurobiology research, facilitating the investigation of neuropeptide signaling pathways and their roles in various physiological processes. Its applications include studying the effects of Y1R modulation on neuroendocrine responses, food intake, and anxiety-related behaviors.
Product Information
Catalog NumA43885
FormulaC62H70N10O10
Molecular Weight1115.28
CAS Number2773476-40-5
SMILESO=C(C1=CC(C(NCCCCOC2=CC=CC([C@@H](C(N[C@H](CCCN/C(N)=N\C(NCCNC(CC)=O)=O)C(NCC3=CC=C(C=C3)O)=O)=O)C4=CC=CC=C4)=C2)=O)=CC=C1C5=C6C=C/C(C=C6OC7=C5C=CC(N(C)C)=C7)=[N+](C)/C)[O-]
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