3BP-3940

Catalog No.: A41622
FAP-Targeting Peptide
3BP-3940 is a highly potent and selective peptide inhibitor targeting fibroblast activation protein (FAP) in cancer-associated fibroblasts (CAFs) within the tumor microenvironment. This reagent exhibits significant potential for tumor imaging when labeled with radionuclides such as Ga-68 and for targeted anticancer therapies using Lu-177. 3BP-3940 selectively accumulates in tumor lesions, making it valuable for the diagnosis and treatment of various solid tumors and conditions related to CAFs.
Grouped product items
Size Price Stock Qty
5mg
$410.00
In stock
10mg
$670.00
In stock
25mg
$1,260.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3BP-3940 is a highly potent and selective peptide inhibitor targeting fibroblast activation protein (FAP) in cancer-associated fibroblasts (CAFs) within the tumor microenvironment. This reagent exhibits significant potential for tumor imaging when labeled with radionuclides such as Ga-68 and for targeted anticancer therapies using Lu-177. 3BP-3940 selectively accumulates in tumor lesions, making it valuable for the diagnosis and treatment of various solid tumors and conditions related to CAFs.
Product Information
Catalog NumA41622
FormulaC66H98N14O18S3
Molecular Weight1471.76
CAS Number2803421-14-7
SequencenBu-CAyl-{Cys(tMeBn(DOTA-AET)-Pro-Pro-Thr-GIn-Phe-Cys}-OH
Sequence shorteningnBu-CAyl-{Cys(tMeBn(DOTA-AET)-PPTQFC}-OH
SMILESO=C1[C@]2(N(C(=O)[C@@H](NC(NCCCC)=O)CSCC=3C=C(C=C(CSCCNC(CN4CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC4)=O)C3)CSC[C@@H](C(O)=O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@]6(N1CCC6)[H])[H])CCC2)[H]
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