Catalog No.
Product Name
Application
Product Information
Citations
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Antioxidant Peptide
Diaminopropionoyl tripeptide-33 is an antioxidant peptide that provides protection against UVA-induced DNA damage in skin cells. This bioactive compound is primarily used in cosmetic formulations to enhance skin cell resilience and promote healthier skin. Its application in research encompasses the study of skin aging and cellular defense mechanisms, making it a valuable component in the development of dermatological products. -
Bioactive Peptide
GAD65 (524-543) is a bioactive peptide derived from the glutamic acid decarboxylase 65 protein. This peptide fragment plays a crucial role in eliciting proliferative T cell responses in the non-obese diabetic (NOD) mouse model of autoimmune diabetes. It serves as a selective stimulus for the diabetogenic T cell clone BDC2.5, enhancing the susceptibility of NOD mice to type 1 diabetes when immunized with GAD65 (524-543). This reagent is valuable for research into T cell activation, autoimmune diabetes mechanisms, and potential therapeutic targets. -
Neuroprotective Peptide
Semax is a synthetic neuroprotective peptide that mimics the adrenocorticotropic hormone (ACTH) and is capable of penetrating the blood-brain barrier. This peptide exhibits notable immunomodulatory and nootropic properties, making it relevant for research into central nervous system disorders. Semax's potential applications include investigations into Alzheimer's disease and cerebral ischemia, where its neuroprotective effects may provide valuable insights. -
α-Peptide
Oligopeptide P11-4 is an α-peptide that self-assembles into β-sheet amyloids, exhibiting hydrogel characteristics at low pH. This oligopeptide demonstrates significant potential in biomimetic mineralization and enamel regeneration, making it applicable in oral care research and development. -
Abeta Degrader
β-Sheet Breaker Peptide iAβ5 is a potent degrader of amyloid-β (Aβ) oligomers, specifically targeting the β-sheet conformation responsible for its aggregation in Alzheimer's disease. This peptide effectively promotes the degradation of fibrillar amyloid deposits in vivo, thereby mitigating the neurotoxic effects associated with Aβ. Additionally, β-Sheet Breaker Peptide iAβ5 can reduce the size and quantity of amyloid plaques while decreasing the activation of IL-1β-positive microglial cells surrounding these deposits. The incorporation of a hydrophobic benzyl alcohol (HBA) tag enables visual detection under acidic conditions, facilitating quantitative analysis in relevant research applications. -
β-Amyloid Peptide Fragment
β-Amyloid (31-35) is a peptide fragment derived from the native Amyloid-β peptide, specifically representing the shortest sequence that maintains neurotoxic functionality. This compound is primarily utilized in research focused on neurodegenerative diseases, particularly Alzheimer's disease, where it aids in the investigation of amyloid plaques and their impact on neuronal health. Its bioactivity makes it a valuable tool for understanding the mechanisms underlying neurotoxicity and for evaluating therapeutic strategies. -
dipeptide
Ile-Phe is a dipeptide known for its ability to self-associate in aqueous solutions, forming a transparent thermoreversible gel through a network of fibrillar nanostructures. This self-assembly property may play a role in biological processes involving amyloid formation and other protein aggregation phenomena. It serves as a valuable tool for studying peptide interactions and the mechanics of gel formation in various biochemical applications. -
Amyloid-β Peptide
β-Amyloid (1-28) is a fragment of the amyloid-β peptide, primarily recognized for its role in metal ion binding. This peptide is significant in the formation of amyloid plaques associated with Alzheimer's disease (AD), making it a critical target for research into AD pathogenesis and potential therapeutic interventions. It is valuable for studies investigating the biochemical pathways involved in neurodegeneration and the development of amyloid-targeting strategies. -
FITC Tagged Aβ1-42 Peptide
FITC-β-Ala-Amyloid β-Protein (1-42) is a fluorescein isothiocyanate (FITC) tagged version of the Aβ1-42 peptide. This peptide is critical in the study of Alzheimer’s disease, as it is involved in the formation of amyloid plaques that are characteristic of the condition. FITC labeling enhances its detectability in various assay formats, making it suitable for studies on peptide aggregation, interaction with receptors, and screening of compounds in Alzheimer's research. -
Amyloid-β Peptide Fragment
β-Amyloid (29-40) is a peptide fragment derived from the Amyloid-β peptide, specifically encompassing amino acids 29 to 40. This fragment plays a significant role in Alzheimer's disease research, as it contributes to the understanding of amyloid plaque formation and neurodegeneration. Its biological activity includes interactions with cellular receptors and modulation of neuroinflammatory responses, making it useful for studying mechanisms of synaptic dysfunction and potential therapeutic interventions in neurodegenerative disorders. -
Aβ Peptide
β-Amyloid (1-38) is a peptide that targets the aggregation of amyloid-beta (Aβ), primarily influencing the conversion of Aβ(1-42) to β-sheet-rich structures. This compound has been shown to reverse the detrimental effects of Aβ(1-42) on long-term potentiation in acute hippocampal slices and enhance membrane conductance in primary neuronal cultures. Additionally, β-Amyloid (1-38) alleviates Aβ(1-42)-related phenotypic changes in Caenorhabditis elegans, making it a valuable tool for research into Alzheimer’s disease and related neurodegenerative processes. -
Polypeptide
(Asp37)-Amyloid β-Protein (1-42) is a G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide, which plays a crucial role in Alzheimer's disease pathology. This modified polypeptide is utilized in research studies investigating protein aggregation, neurotoxicity, and the mechanisms underlying amyloid plaque formation. Its unique properties make it an important tool for examining the functional consequences of mutations within the Amyloid-beta sequence. -
Amyloid-β Peptide
β-Amyloid (15-21) is a peptide fragment derived from the Amyloid-β peptide, primarily targeting amyloid aggregation pathways. It is essential for the study of Alzheimer's disease mechanisms and the investigation of neurodegenerative processes associated with amyloid pathology. This reagent aids in elucidating the role of amyloid plaques in neuronal toxicity and offers insights into potential therapeutic interventions. -
Bioactive Peptide
[D-Ser14]-Humanin is a modified bioactive peptide targeting amyloid-β fibrillation. This D-form variant exhibits enhanced protective effects against oxidative stress and cellular death compared to its L-form counterpart, Humanin. Its potent inhibitory activity makes [D-Ser14]-Humanin a valuable tool in Alzheimer's disease research, particularly in studies focused on amyloid-related neurotoxicity and cellular resilience. -
Bioactive Peptide
Biotin-Ahx-β-Amyloid (1-40) is a biotinylated bioactive peptide that targets amyloid-beta, a key component implicated in Alzheimer's disease pathology. This compound facilitates the study of amyloid aggregation and provides valuable insights into the mechanisms of neurodegeneration. Research applications include the exploration of amyloid-beta's role in cellular toxicity and the development of therapeutic strategies for Alzheimer's disease. -
Oligopeptide Capable Of Self-assembling Into Nanotubes
AAKLVFF is an oligopeptide known for its ability to self-assemble into nanotubes. It is derived from the core section of β-amyloid and serves as a methanol-compatible liquid crystal alignment medium, facilitating residual dipolar coupling measurements. This property enhances its application in structural studies of protein interactions and dynamics, making it a valuable tool in biochemical and biophysical research. -
Bioactive Peptide
Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 is a bioactive peptide designed as a substrate for matrix metalloproteinases (MMPs). This compound exhibits specific enzymatic activity that facilitates studies on MMP-mediated processes, such as tissue remodeling and extracellular matrix degradation. It serves as a valuable tool in research applications focused on cancer metastasis, wound healing, and various inflammatory conditions linked to MMP activity. -
Tripeptide
Lysyl-phenylalanyl-lysine is a tripeptide that effectively activates LAP-TGF-β1, facilitating the release of active TGF-β1. This compound plays a crucial role in regulating the expression of matrix metalloproteinases (MMPs), thus contributing to the modulation of tissue remodeling processes. Lysyl-phenylalanyl-lysine is valuable for research into skin aging-related diseases and impaired wound healing mechanisms. -
Cross-Linked Peptide
C-telopeptide is a cross-linked peptide derived from type I collagen, released during the process of bone resorption. It serves as a valuable biomarker for assessing bone health, as its levels correlate with bone mineral density (BMD). This reagent is essential for research applications focused on osteoporosis, bone metabolism, and related pathologies. -
Bioactive Peptide
Noxa A BH3 is a bioactive peptide that corresponds to the BH3 domain of the Noxa protein. This peptide is known to induce apoptosis through its interaction with pro-survival Bcl-2 proteins, thereby promoting cell death in cancer cells. It serves as a valuable tool for research in apoptosis mechanisms and therapeutic development targeting Bcl-2 family proteins. -
Bioactive Peptide
Noxa B BH3 is a bioactive peptide that targets the BH3 domain of the Noxa protein. It plays a crucial role in regulating apoptosis by promoting mitochondrial outer membrane permeabilization. This peptide is useful for studying cellular mechanisms of programmed cell death and exploring potential therapeutic interventions in cancer and other diseases associated with dysregulated apoptosis. -
Tetrapeptide
[Des-Tyr1]-Met-Enkephalin is a tetrapeptide that serves as a degradation product of enkephalins. This compound is primarily known for its role in modulating pain and providing analgesic effects through interactions with opioid receptors. It is utilized in research applications focused on pain management, neurobiology, and the study of endogenous peptide systems. -
Chromogenic Peptide Substrate
H-Gly-Glu-pNA is a chromogenic peptide substrate primarily utilized for enzymatic analysis, specifically in the detection of trypsin and urokinase-type plasminogen activator (uPA). This substrate allows for the sensitive measurement of enzymatic activity, facilitating research in areas such as proteolytic enzyme studies, clinical diagnostics, and biochemical assay development. Its ability to produce a measurable chromogenic signal makes it an essential tool for researchers investigating protease activity and related biological processes. -
Beauty Peptide
Acetyl hexapeptide-38 is a beauty peptide that enhances tissue repair by targeting fibroblasts in the dermis. Its primary mechanism involves promoting collagen synthesis and thickening subcutaneous fat, facilitating the skin's natural repair processes. Key biological activities include increasing collagen content and improving skin tissue structure, making it useful in cosmetic applications such as repairing congenital soft tissue defects, reducing tear grooves and nasolabial folds, and minimizing postoperative scars. This peptide is also applicable in micro-plastic surgery for skin tissue enhancement. -
Dipeptide
Prolylisoleucine (Pro-Ile) is a dipeptide consisting of proline and isoleucine, primarily known for its ability to inhibit endopeptidase 24.16. This compound exhibits significant biological activity by modulating peptide metabolism, making it a valuable tool in research focused on neuropeptide regulation and enzymatic pathways. Prolylisoleucine can be utilized in studies investigating the roles of neuropeptides in various physiological processes. -
Nrf2 Peptide
Nrf2 (69-84) is a peptide derived from the Nrf2 protein, featuring the essential ETGE motif critical for binding to the Kelch domain of the Keap1 protein. This peptide serves as a valuable tool for investigating the regulatory functions of Nrf2 in various biological processes, particularly in the context of cancer, neurodegenerative disorders, and inflammatory diseases. Its application aids in elucidating the mechanisms by which Nrf2 modulates cellular responses to oxidative stress and inflammation. -
Bioactive Peptide
Keap1-Nrf2-IN-16 is a bioactive peptide that targets the KEAP1 protein to disrupt its interaction with the Nrf2 transcription factor. This inhibition leads to the stabilization and activation of Nrf2, promoting the expression of antioxidant response elements and enhancing cellular defense mechanisms. Keap1-Nrf2-IN-16 is utilized in research applications related to oxidative stress, cellular protection, and neurodegenerative diseases. -
NF-κB Inhibitor
NBD peptide is a selective inhibitor of the NF-κB signaling pathway, acting by disrupting the interaction between NEMO and the IKK complex. This inhibition leads to reduced production of pro-inflammatory cytokines, showcasing its anti-inflammatory properties. Additionally, NBD peptide demonstrates immunosuppressive effects through modulation of immune cell activity. The incorporation of the cell-penetrating HIV-TAT peptide enhances its cellular uptake, facilitating its application in various research contexts. -
NF-κB Inhibitor
IKKγ NBD Inhibitory Peptide is a selective inhibitor of NF-κB signaling. It functions by disrupting the interaction between the IKKγ/NEMO-binding domain and IKKα/IKKβ, effectively blocking TNF-α-induced NF-κB activation. This peptide exhibits significant anti-inflammatory properties and has potential applications in studying cerebral ischemia and its associated neurological deficits. -
Control Peptide
SN50M is a mutant peptide derived from SN50 that serves as a cell membrane-permeable inactive control peptide. This reagent is primarily utilized in research to study the effects and mechanisms of active peptides targeting the nuclear transport pathway. Its role as a control allows for the differentiation of specific biological responses in cellular assays and molecular studies. -
β-Amyloid Peptide Fragment
β-Amyloid (1-38), mouse, rat is a peptide fragment consisting of the first 38 amino acids of the amyloid-beta (Aβ) peptide. This fragment plays a crucial role in the formation of amyloid plaques associated with Alzheimer's disease. It serves as an important tool for researchers studying the pathophysiology of neurodegeneration and the mechanisms of Alzheimer's pathology. Its use can provide insights into β-amyloid aggregation and the development of potential therapeutic strategies. -
Peptide Fragment
(D-Asp1)-Amyloid β-Protein (1-42) is a peptide fragment derived from amyloid β-protein (Aβ), which plays a crucial role in the pathogenesis of Alzheimer's disease. This fragment is implicated in the formation of amyloid plaques, a hallmark of neurodegeneration associated with the disease. The compound is utilized in research applications focused on studying amyloid aggregation, neuroinflammation, and potential therapeutic interventions in Alzheimer's disease. -
β-Amyloid Peptide Fragment
β-Amyloid (1-34) is a fragment of the β-Amyloid peptide consisting of 34 amino acids. This peptide is involved in the formation of extracellular plaques in Alzheimer's disease and serves as a critical target for studying neurodegenerative processes. β-Amyloid (1-34) is utilized in research applications focusing on the pathology of Alzheimer's, neuroinflammation, and potential therapeutic interventions targeting amyloid aggregation. -
Bioactive Peptide
RERMS are bioactive peptides derived from the active regions of amyloid-β and A4 protein precursors, known to enhance fibroblast growth. These peptides serve as valuable tools in the investigation of neurodegenerative diseases, aiding in the understanding of cellular mechanisms and potential therapeutic pathways. Their ability to promote fibroblast proliferation highlights their significance in biomedical research. -
APP Peptide Fragment
β-Amyloid/A4 Protein Precursor (319-335) is a peptide fragment of the amyloid precursor protein (APP) that focuses on its crucial role in cell signaling and neuritotropic activity. This fragment targets a heparinase-insensitive site associated with the neurotrophic functions of APP, making it valuable for research into neurodegenerative diseases such as Alzheimer's. Its applications include studies on neurodevelopment, synaptic plasticity, and the mechanisms underlying amyloid pathology. -
Aβ Peptide Fragment
Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) is a peptide fragment that targets the amyloid β-protein (Aβ), a key component in the pathogenesis of Alzheimer's disease. This peptide is instrumental in studying the formation and aggregation of amyloid plaques, which are hallmark features of Alzheimer's pathology. Researchers can utilize this reagent to explore the mechanisms of neurodegeneration and potential therapeutic interventions in Alzheimer's disease. -
Aβ Peptide Binder
BTA-EG6 is a brain-penetrant binder that selectively targets aggregated amyloid-β (Aβ) peptides, exhibiting a dissociation constant (Kd) of 290 nM for Aβ1-42. This compound forms protective protein-resistive coatings that inhibit interactions between Aβ and catalase, thereby reducing neurotoxic effects. In functional assays, BTA-EG6 demonstrates protective effects against Aβ-induced cytotoxicity and oxidative stress, effectively decreasing hydrogen peroxide (H2O2) levels in neuroblastoma cells. This reagent is valuable for research focusing on Alzheimer’s disease (AD) and associated mechanisms of neurotoxicity. -
β-Amyloid Peptide Fragment
β-Amyloid (12-20) is a peptide fragment of the β-Amyloid protein, primarily targeting amyloid plaques involved in Alzheimer's disease pathology. This peptide is utilized in research to study the aggregation and toxicity of β-Amyloid in neural tissues. Its applications extend to understanding the molecular mechanisms underlying neurodegenerative disorders and assessing potential therapeutic interventions. -
β-amyloid Peptide
β Amyloid(28-35) human is a key fragment of the β-amyloid peptide (Abeta) that plays a critical role in Alzheimer's disease pathology. This peptide is known to form neurotoxic oligomers that interact with neuronal membranes, altering their secondary structure and contributing to neurodegenerative processes. Additionally, β Amyloid(28-35) human affects the fluidity of lipid membrane bilayers, particularly in relation to the acidic phospholipid DPH, making it valuable for research into amyloid-related neurotoxicity and membrane dynamics. -
Superoxide Dismutase Peptide
SOD1 (147-153) human is a peptide derived from the Cu/Zn superoxide dismutase (SOD1), known for its propensity to form amyloid fibrils. This peptide fragment is implicated in the aggregation of full-length SOD1, serving as a significant molecular determinant in both familial and sporadic amyotrophic lateral sclerosis (fALS and sALS). Research applications include studies on neurodegenerative disease mechanisms and the investigation of protein aggregation processes. -
Aβ Fibrillogenic Inhibitor
Acetyl-Tau Peptide (273-284) amide is an acetylated fragment of the Tau protein that acts as an inhibitor of Aβ fibrillogenesis. It effectively reduces the aggregation of Ac-Aβ(25–35)-NH2, facilitating studies on the interplay between Aβ and Tau proteins. This peptide serves as a valuable experimental tool for investigating the mechanisms underlying Alzheimer's disease and related neurodegenerative conditions. -
β-Amyloid Peptide Fragment
β-Amyloid (1-17) is a peptide fragment of β-Amyloid that is involved in the stabilization of amyloid fibrils. This fragment plays a crucial role in the formation and aggregation of amyloid-beta aggregates, which are implicated in neurodegenerative diseases such as Alzheimer's. Research applications include studies on amyloid fibril behavior and the investigation of β-Amyloid's role in neural pathologies. -
Bioactive Peptide
Scrambled β-amyloid (1-40) is a bioactive peptide that functions as a structural variant of the β-amyloid protein. This peptide mimics the assembly characteristics of the major C-terminal variants Aβ (1-40) and Aβ (1-42), both of which contribute to amyloid plaque formation in Alzheimer's disease. Research applications include the study of amyloid aggregation processes and examination of peptide interactions within neurodegenerative contexts. -
Neuroprotective Peptide
Pep63 is a neuroprotective peptide with the sequence VFQVRARTVA that acts primarily by competitively binding to Aβ1-42 oligomers. It effectively inhibits the formation of Aβ fibers and has been shown to enhance synaptic plasticity and memory retention. Pep63 is a valuable tool for research into Alzheimer's disease and other neurodegenerative disorders, facilitating the investigation of neuroprotective mechanisms and potential therapeutic interventions. -
β-amyloid Peptide
β-Amyloid (1-16) rat is a fragment of the β-amyloid peptide (Aβ) featuring a metal-binding domain. This synthetic peptide contains three amino acid substitutions that make it distinct from the human form, resulting in reduced susceptibility to amyloid-related neurodegeneration in rodent models. It is primarily utilized in research applications focused on Alzheimer's disease mechanisms and the study of amyloid pathology. -
insoluble amyloid β-peptide deposits
(Pyr3)-Amyloid β-Protein (3-42) targets insoluble amyloid β-peptide deposits, playing a critical role in the pathogenesis of Alzheimer's disease and Down's syndrome. This peptide variant is known to accumulate in the brain, potentially initiating the formation of pathological amyloid aggregates. It is useful in research applications focused on understanding amyloid-related neurodegeneration and developing therapeutic strategies. -
Aβ1-42 targeting peptide
QSH peptide is a targeting peptide that specifically binds to the amyloid-beta peptide Aβ1-42, a key player in Alzheimer's disease pathology. It is utilized in the development of siRNA delivery complexes, facilitating targeted therapeutic approaches. This peptide is essential for research focused on understanding and potentially mitigating the effects of amyloid-beta in Alzheimer's disease. -
β-Amyloid Peptide Fragment
β-Amyloid (13-27) is a peptide fragment derived from the β-amyloid protein, encompassing amino acids 13 to 27. This fragment plays a crucial role in studies related to Alzheimer's disease and neurodegenerative disorders. Its biological activity is relevant for research applications focusing on amyloid aggregation, neurotoxicity, and potential therapeutic interventions targeting amyloid pathology. -
Amyloid-β
Glp-Amyloid-β (3-40) peptide (human) specifically targets amyloid-β, a critical factor in Alzheimer's disease pathology. This peptide contains a pyroglutamate modification and is derived from 24-month-old transgenic mice expressing amyloid precursor protein (APP). It is useful for research applications involving the study of amyloid plaque formation, neuroinflammation, and the development of potential therapeutic strategies for neurodegenerative diseases. -
Mutant peptide of Aβ(25-35)
[Ala28]-β Amyloid(25-35) is a modified peptide variant of Aβ(25-35) that carries an electrically neutral charge. This alteration enhances the aggregation properties of the peptide, making it a valuable tool in studies of amyloid aggregation and Alzheimer’s disease pathology. It is particularly useful in research applications focused on therapeutic strategies that target amyloid-beta aggregation and its effects on cellular processes such as luciferase activity.
