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β-Amyloid (1-28)

Catalog No.: A78267
Amyloid-β Peptide
β-Amyloid (1-28) is a fragment of the amyloid-β peptide, primarily recognized for its role in metal ion binding. This peptide is significant in the formation of amyloid plaques associated with Alzheimer's disease (AD), making it a critical target for research into AD pathogenesis and potential therapeutic interventions. It is valuable for studies investigating the biochemical pathways involved in neurodegeneration and the development of amyloid-targeting strategies.
β-Amyloid (1-28) 109770-29-8 Amyloid-β Peptide
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Size Price Stock Qty
1mg
$70.00
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5mg
$295.00
In stock
10mg
$460.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Amyloid (1-28) is a fragment of the amyloid-β peptide, primarily recognized for its role in metal ion binding. This peptide is significant in the formation of amyloid plaques associated with Alzheimer's disease (AD), making it a critical target for research into AD pathogenesis and potential therapeutic interventions. It is valuable for studies investigating the biochemical pathways involved in neurodegeneration and the development of amyloid-targeting strategies.
Product Information
Catalog NumA78267
FormulaC145H209N41O46
Molecular Weight3262.51
CAS Number109770-29-8
SequenceAsp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys
Sequence shorteningDAEFRHDSGYEVHHQKLVFFAEDVGSNK
SMILES[C@@H](CC1=CN=CN1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CC(O)=O)=O)CO)=O)=O)=O)CCC(O)=O)=O)C(C)C)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CC7=CC=CC=C7)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)=O)C(C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O
SynonymsAmyloid β-Protein (1-28)
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