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Noxa B BH3

Catalog No.: A76918
Bioactive Peptide
Noxa B BH3 is a bioactive peptide that targets the BH3 domain of the Noxa protein. It plays a crucial role in regulating apoptosis by promoting mitochondrial outer membrane permeabilization. This peptide is useful for studying cellular mechanisms of programmed cell death and exploring potential therapeutic interventions in cancer and other diseases associated with dysregulated apoptosis.
Noxa B BH3 505070-10-0 Bioactive Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNoxa B BH3 is a bioactive peptide that targets the BH3 domain of the Noxa protein. It plays a crucial role in regulating apoptosis by promoting mitochondrial outer membrane permeabilization. This peptide is useful for studying cellular mechanisms of programmed cell death and exploring potential therapeutic interventions in cancer and other diseases associated with dysregulated apoptosis.
Product Information
Catalog NumA76918
FormulaC95H164N30O31S
Molecular Weight2254.57
CAS Number505070-10-0
SequencePro-Ala-Asp-Leu-Lys-Asp-Glu-Cys-Ala-Gln-Leu-Arg-Arg-Ile-Gly-Asp-Lys-Val-Asn-Leu
Sequence shorteningPADLKDECAQLRRIGDKVNL
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCCN1)C)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(O)=O)=O)CCC(O)=O)=O)CS)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CC(N)=O)=O)C(C)C)=O)CCCCN)=O)CC(O)=O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N
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