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Acetyl-ACTH (3-24) (human, bovine, rat)

Catalog No.: A85005
ACTH Peptide
Acetyl-ACTH (3-24) is a synthetic peptide derived from proopiomelanocortin (POMC), specifically acting on the adrenocorticotrophic hormone (ACTH) pathway. This fragment plays a pivotal role as an agonist at the melanocortin-1 receptor (MC-1), influencing various physiological processes. Acetyl-ACTH (3-24) is utilized in research applications exploring stress response, skin pigmentation, and metabolic regulation. It serves as a valuable tool for studies related to the biological actions of melanocortin peptides.
Acetyl-ACTH (3-24) (human, bovine, rat) 1815617-99-2 ACTH Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAcetyl-ACTH (3-24) is a synthetic peptide derived from proopiomelanocortin (POMC), specifically acting on the adrenocorticotrophic hormone (ACTH) pathway. This fragment plays a pivotal role as an agonist at the melanocortin-1 receptor (MC-1), influencing various physiological processes. Acetyl-ACTH (3-24) is utilized in research applications exploring stress response, skin pigmentation, and metabolic regulation. It serves as a valuable tool for studies related to the biological actions of melanocortin peptides.
Product Information
Catalog NumA85005
FormulaC126H198N38O28S
Molecular Weight2725.22
CAS Number1815617-99-2
SequenceAc-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Sequence shorteningAc-SMEHFRWGKPVGKKRRPVKVYP
SMILESCSCC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O
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