Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
17-((tert-Butoxycarbonyl)amino)heptadecanoic acid functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the targeted degradation of specific proteins, playing a crucial role in cellular function studies and therapeutic applications. Its unique linker chemistry is essential for the effective conjugation of targeting moieties to E3 ligases. -
PROTAC Linker
tert-Butyl N-(2-azaspiro[3.3]heptan-6-yl)carbamate hydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the construction of bifunctional molecules that can selectively induce ubiquitination and degradation of target proteins. Its application is crucial for studies in targeted protein degradation and drug discovery research. -
PROTAC Linker
1-(1-(3-Chloropropyl)piperidin-4-yl)ethan-1-ol serves as a PROTAC linker, facilitating the development of Proteolysis-targeting chimeras (PROTACs). This compound effectively connects the target protein to an E3 ligase, thereby inducing targeted protein degradation. It is instrumental in research applications focused on drug discovery and the study of protein function regulation through degradation pathways. -
PROTAC Linker
9-Chlorononan-1-ol is a versatile PROTAC linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins via the ubiquitin-proteasome system, making it a valuable tool in drug discovery and development. Its unique structure enhances the design of bifunctional molecules aimed at modulating protein levels, contributing to advancements in targeted protein degradation research. -
PROTAC Linker
Benzyl (6-aminohexyl)carbamate hydrochloride is a novel PROTAC linker designed to facilitate the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enhancing the efficacy of targeted protein degradation by linking ligands to E3 ligase recruiters. Its application in PROTAC synthesis supports research in targeted therapy, enabling investigations into cellular processes and the degradation of specific proteins for therapeutic benefits. -
PROTAC Linker
1-(Piperidin-4-yl)azetidin-3-ol dihydrochloride functions as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its structural properties enable effective recruitment of E3 ubiquitin ligases, promoting targeted protein degradation. This reagent is vital for researchers exploring novel therapeutic strategies in drug development and cellular regulation. -
PROTAC Linker
Di-tert-butyl decanedioate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the construction of bifunctional molecules that can selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. This compound is essential for researchers developing innovative therapeutic strategies focused on protein modulation and targeted protein degradation. -
PROTAC Linker
tert-Butyl 4-(2-Aminoethyl)-3,3-difluoropiperidine-1-carboxylate functions as a PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound is key in the design of bifunctional molecules that modify protein stability and promote targeted degradation in cellular systems. Its structural properties make it suitable for applications in targeted protein degradation research and drug discovery. -
PROTAC Linker
N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This linker facilitates the conjugation of target proteins with an E3 ligase component, promoting selective protein degradation. Its unique structure enhances solubility and biocompatibility, making it suitable for various biological research applications in targeted protein degradation studies. -
PROTAC Linker
Cbz-PEG4-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by linking a ligand to an E3 ligase, thereby enabling targeted protein modulation. Its application in PROTAC development is crucial for advancing research in targeted therapy and understanding protein dynamics within cellular systems. -
PROTAC Linker
Tert-butyl (7-iodoheptyl)carbamate acts as a versatile PROTAC linker essential for the construction of PROTAC molecules. This compound facilitates targeted protein degradation by connecting a ligand to an E3 ligase, thereby enhancing the selectivity and efficiency of proteolysis. Its application is significant in drug discovery and development, particularly for therapeutics aimed at modulating protein levels in various disease models. -
PROTAC Linker
TBS-PEG5-OH is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras) compounds. This linker facilitates the assembly of the warhead and E3 ligase components, enhancing the efficiency of targeted protein degradation. TBS-PEG5-OH is pertinent for researchers exploring novel therapeutic strategies in drug discovery and development focused on protein regulation mechanisms. -
PROTAC Linker
Methyl 5-oxopentanoate serves as a PROTAC linker, facilitating the design and synthesis of PROteolysis TARGETing chimeras (PROTACs). Its primary mechanism involves connecting a ligand that recruits an E3 ligase to a target protein, promoting ubiquitination and degradation. This compound is instrumental in targeted protein degradation research, enabling the exploration of therapeutic applications in cancer and other diseases. -
PROTAC Linker
2-(3-(Aminomethyl)phenyl)acetic acid functions as a PROTAC linker, facilitating the development of targeted protein degraders. This compound is instrumental in synthesizing DU-14, a specific PROTAC targeting PTP1B and TC-PTP, thereby enabling precise modulation of protein levels in cellular studies. Its application in research underscores its significance in advancing therapeutic strategies through selective degradation of proteins. -
PROTAC Linker
Deca-1,9-diyne is a PROTAC linker known for its effectiveness in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to specific target proteins, promoting targeted degradation. Its unique structure enables the design of advanced therapeutic agents for research applications in protein degradation and modulation of cellular pathways. -
PROTAC Linker
4-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-4-oxobutanoic acid functions as a PROTAC linker, facilitating the conjugation of target proteins for targeted degradation. This compound is crucial in the synthesis of PROTACs, enabling the study of protein homeostasis and regulation in various biological contexts. It serves as a valuable tool for researchers investigating the therapeutic potential of targeted protein degradation. -
PROTAC Linker
Tert-butyl 4-(4-(hydroxymethyl)benzyl)piperazine-1-carboxylate is an innovative PROTAC linker designed for the development of proteolysis-targeting chimeras. This compound facilitates the targeted degradation of specific proteins by linking E3 ligases to protein substrates, enabling the study of protein function and regulation. Its application in PROTAC synthesis makes it a valuable tool in drug discovery and therapeutic research. -
PROTAC Linker
HO-PEG3-(CH2)6-Cl is a versatile PROTAC linker designed for the synthesis of HaloPROTAC-E. This compound enables the efficient conjugation of E3 ligase recruiters with target proteins, facilitating targeted protein degradation mechanisms. Its utility in chemical biology research supports the development of innovative therapeutic modalities by enhancing the specificity and efficacy of protein modulation strategies. -
PROTAC Linker
Ph-PEG5-Br is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. It enhances the bioavailability and solubility of PROTAC molecules, making it a valuable component in the synthesis of innovative therapeutic agents. Its unique structure provides a stable connection between targeting ligands and E3 ligases, enabling efficient cellular degradation of select proteins. This compound is ideal for researchers focused on drug discovery and development in the field of targeted therapies. -
PROTAC Linker
(((6-Bromohexyl)oxy)methyl)benzene serves as a versatile PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enables targeted protein degradation, making it crucial for the development of innovative therapeutic strategies in cancer and other diseases. Its unique structural properties allow for efficient coupling and enhance the specificity of PROTACs in biological research applications. -
PROTAC Linker
Tert-butyl 3-(((benzyloxy)carbonyl)amino)propanoate is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its structural features enhance the efficacy of target protein degradation, making it a valuable tool for chemical biology research. This compound is instrumental in the design and synthesis of novel therapeutic agents aimed at modulating protein levels in various biological contexts. -
PROTAC Linker
Phenylmethyl N-(5-bromopentyl)carbamate serves as a PROTAC linker for the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the construction of bifunctional molecules that can selectively degrade target proteins through the ubiquitin-proteasome system. It is essential in chemical biology for drug discovery research and targeted protein degradation studies. -
PROTAC Linker
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by connecting a target protein ligand to an E3 ligase ligand through a flexible linker. Its versatility is crucial for studies in targeted protein degradation and drug discovery applications. -
PROTAC Linker
tert-Butyl 4-(piperidin-3-ylmethyl)piperazine-1-carboxylate dihydrochloride is a versatile PROTAC linker designed for use in the synthesis of targeted protein degradation compounds. This linker facilitates the formation of PROTACs by enabling the recruitment of E3 ligases to target proteins, thereby promoting ubiquitination and subsequent proteasomal degradation. Its applications include advancing research in drug discovery and mechanism-based studies of protein regulation. -
PROTAC Linker
N,N'-(Pentane-1,5-diyl)bis(2-chloroacetamide) is a PROTAC linker designed for the synthesis of protein-targeting chimeras. This compound facilitates the formation of proteolysis-targeting chimeras (PROTACs) by connecting an E3 ligase ligand with a target protein. It is utilized in drug discovery and development, enabling the selective degradation of proteins for therapeutic applications. -
PROTAC Linker
2-Bromo-N-(but-3-yn-1-yl)acetamide serves as a linker for PROTAC (Proteolysis Targeting Chimeras) synthesis, facilitating the assembly of bifunctional molecules that can induce targeted protein degradation. Its structure allows for effective conjugation to both ligand and ligand-recruiting moieties, essential for the design of novel therapeutic agents. This compound is instrumental in research focused on targeted protein degradation and the development of innovative treatment strategies in various diseases. -
PROTAC Linker
Cbz-NH-PEG3-tosyl is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) spacer enhances solubility and flexibility, facilitating efficient conjugation to various target proteins and E3 ligases. This linker is essential for developing novel therapeutic strategies in targeted protein degradation research. -
PROTAC Linker
(R)-tert-Butyl 3-(2-aminoethyl)pyrrolidine-1-carboxylate is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficiency of target protein degradation by connecting the ligand and E3 ligase components within PROTAC constructs. It is instrumental in the synthesis of novel PROTACs for therapeutic applications in oncology and other fields requiring targeted protein modulation. -
PROTAC Linker
Methyl 6-aminospiro[3.3]heptane-2-carboxylate hydrochloride serves as an effective linker for PROTAC (Proteolysis Targeting Chimera) synthesis. This compound facilitates the development of innovative targeted protein degradation technologies, enabling selective modulation of protein levels in various biological systems. Its unique structural characteristics contribute to the stability and efficacy of PROTACs, making it a valuable reagent for researchers investigating therapeutic applications in cancer and other diseases. -
PROTAC Linker
(4-Oxo-4H-quinazolin-3-yl)-acetic acid is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras. This compound enables targeted degradation of specific proteins by connecting a ligand for the protein of interest with an E3 ligase recruiter. Its application in molecular biology and pharmacological research can enhance drug discovery efforts by promoting the selective elimination of undesirable proteins. -
PROTAC Linker
PEG3-I is a PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the binding efficiency and cellular uptake of PROTACs, thereby promoting targeted protein degradation. PEG3-I is particularly valuable in the development of therapeutic agents aimed at modulating protein levels for various research applications, including cancer biology and drug discovery. -
PROTAC Linker
Tetrahydro-2-[[(3E)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-buten-1-yl]oxy]-2H-pyran serves as an effective PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is critical for the development of targeted protein degradation strategies, enabling researchers to selectively degrade specific proteins within cellular environments. Its unique structural properties assist in enhancing the efficacy of PROTACs for various therapeutic applications. -
PROTAC Linker
tert-Butyl 4-(2-aminoethyl)-3-oxopiperazine-1-carboxylate is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a versatile building block for synthesizing targeted protein degradation systems. Its unique structural features enable effective binding interactions, making it suitable for various applications in drug discovery and biochemical research related to protein regulation. -
PROTAC Linker
Tert-butyl (2-aminospiro[3.5]nonan-7-yl)(methyl)carbamate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, facilitating studies in cellular processes and therapeutic interventions. Its unique structure enhances the efficiency of PROTAC assembly, making it a valuable tool for researchers in drug discovery and protein regulation studies. -
PROTAC Linker
Methyl 2-(chlorosulfonyl)acetate is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the specificity and efficacy of targeted protein degradation strategies. Its application in research contributes to advancements in drug discovery and therapeutic development by enabling the effective modulation of protein levels in various biological systems. -
PROTAC Linker
2-(Hydroxymethyl)cyclopropanecarbonitrile serves as an effective linker in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the development of targeted protein degradation strategies by connecting the ligand to the E3 ubiquitin ligase. Its unique structural properties enhance the stability and functionality of the resulting PROTACs, supporting investigations into modulating protein levels for therapeutic applications. -
PROTAC Linker
But-3-yn-1-yl methanesulfonate is a key PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins through the recruitment of E3 ligases, promoting targeted protein modulation. It serves as a critical building block for researchers developing novel therapeutic strategies in oncology and other fields of biomedical research. -
PROTAC Linker
tert-Butyl (3-(chlorosulfonyl)propyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of bifunctional molecules that promote targeted protein degradation, offering insights into cellular processes and potential therapeutic applications. Its chemical structure allows for the efficient conjugation of ligands, enhancing the specificity and effectiveness of PROTAC assays in research settings. -
PROTAC Linker
2-(2,6-Dimethylpiperazin-1-yl)ethan-1-amine serves as a potent PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the synthesis of PROTAC molecules, enabling selective degradation of target proteins. Its versatile structure and reactivity make it a valuable tool in chemical biology research focused on targeted protein degradation strategies. -
PROTAC Linker
[1,1'-Bi(cyclohexane)]-4,4'-diol serves as a versatile linker for the development of PROTACs (proteolysis-targeting chimeras). This compound facilitates the selective degradation of target proteins by linking an E3 ubiquitin ligase to a protein of interest, thereby enabling targeted protein modulation and degradation. Its structure allows for the tuning of pharmacokinetic properties, making it suitable for various biological studies in targeted protein degradation research. -
PROTAC Linker
1-(2-(tert-Butoxy)-2-oxoethyl)piperidine-4-carboxylic acid functions as a PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound plays a crucial role in the development of targeted protein degradation strategies, enabling researchers to investigate protein function and develop novel therapeutic approaches. Its structural characteristics make it suitable for creating diverse PROTAC constructs aimed at selective modulation of protein activity in various biological contexts. -
PROTAC Linker
Tert-butyl n-methyl-N-[2-(piperidin-4-yl)ethyl]carbamate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of ligands to E3 ubiquitin ligases, enabling targeted degradation of specific proteins. Its application in drug discovery allows for the investigation of protein function and the development of novel therapeutic strategies in various disease models. -
PROTAC Linker
Ethyl 2-(trans-4-aminocyclohexyl)acetate is a PROTAC linker designed for the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, promoting ubiquitination and subsequent degradation of specific proteins within cells. It is particularly valuable in chemical biology and drug discovery for studying protein interactions and regulation. -
PROTAC Linker
BnO-PEG4-CH2COOH is a PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) moiety enhances solubility and biocompatibility, making it suitable for a variety of biological applications. This linker is crucial for the development of novel therapeutic agents that selectively degrade target proteins, thereby advancing research in targeted protein degradation. -
PROTAC Linker
PEG4-NH-Cbz is a polyethylene glycol (PEG) based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the development of bifunctional molecules that promote the selective degradation of target proteins via the ubiquitin-proteasome system. PEG4-NH-Cbz enhances solubility and stability in biological systems, making it suitable for various applications in medicinal chemistry and targeted protein degradation research. -
PROTAC Linker
Methyl-Bn-PEG3-OH is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, enabling the investigation of protein function and signaling pathways. Its unique structure allows for enhanced solubility and improved pharmacokinetic properties, making it a valuable tool in chemical biology and drug discovery research. -
PROTAC Linker
Methyl 3-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylate is a PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by harnessing the cellular ubiquitin-proteasome system. It is suitable for research applications aimed at developing novel therapeutics through targeted protein degradation strategies. -
PROTAC Linker
Methyl benzenesulfonic acid-PEG3-O-NO2 serves as a versatile PROTAC linker, enabling the construction of bifunctional small molecules designed for targeted protein degradation. Its unique structure facilitates the conjugation of target proteins with E3 ligases, promoting ubiquitination and subsequent proteasomal degradation. This compound is essential for researchers focusing on protein modulation and therapeutic development in cancer and other diseases. -
PROTAC Linker
tert-Butyl (11-bromoundecyl)carbamate serves as a versatile PROTAC linker, facilitating the formation of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by promoting E3 ligase-mediated ubiquitination. Its application in chemical research aids in the development of novel therapeutic strategies for diseases driven by protein dysregulation. -
PROTAC Linker
Benzyl (5-oxopentyl)carbamate serves as an effective PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structural attributes enhance binding efficiency and specificity, making it valuable for research applications in chemical biology and targeted therapeutics. This compound is suitable for the development and optimization of novel PROTAC strategies aimed at degrading specific proteins within cellular pathways.
