Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
Ph-PEG9-NH2 is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the connection between E3 ligases and target proteins, enabling targeted protein degradation. Its application is crucial in research focused on protein regulation and therapeutic development in oncology and other disease areas. -
PROTAC Linker
Methyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling the selective degradation of unwanted proteins within cells. This compound is essential for researchers exploring novel therapeutic approaches in areas such as cancer and neurodegenerative diseases through targeted protein degradation. -
PROTAC Linker
NHBoc-PEG4-methyl acetate is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). Its flexible PEG4 spacer enhances solubility and bioavailability, facilitating targeted protein degradation. This compound is essential for researchers investigating novel therapeutic strategies involving targeted protein modulation through the use of PROTAC technology. -
PROTAC Linker
Ethyl 3-(piperidin-4-yl)propanoate serves as an efficient PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the ability to design and study targeted protein degradation pathways. Its application in chemical biology research supports advances in therapeutic development and targeted modulation of protein function. -
PROTAC Linker
HS-PEG6-CH2CH2-Boc is a polyethylene glycol (PEG) based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the effective conjugation of target proteins to E3 ligases, enabling selective degradation of intracellular proteins. Its utility in chemical biology makes it valuable for researchers focusing on targeted protein degradation and therapeutic interventions in various disease models. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-tosyl is a PROTAC linker designed for targeted protein degradation applications. Featuring an E3 ligase ligand and a PEG4 spacer, this compound enhances solubility and hydrophilicity, facilitating improved delivery in biological systems. The tosyl group enables reactivity with amines and other nucleophiles, making it a versatile tool in drug research and discovery. -
PROTAC Linker
4-Chloro-1-butyne serves as a potent PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, allowing for targeted degradation of specific proteins in cellular systems. It is particularly useful in studies focused on protein interactions and modulation of cellular pathways. -
PROTAC Linker
4,4'-(Propane-1,3-diylbis(oxy))dianiline serves as an effective PROTAC linker, facilitating the development of PROTAC (proteolysis-targeting chimeras) compounds. By linking a target protein to an E3 ubiquitin ligase, this compound enhances the targeted degradation of specific proteins, making it invaluable for research in cellular regulation and therapeutic development. Its usage is pivotal in studies aimed at understanding protein homeostasis and targeted drug design. -
PROTAC Linker
Tert-Butyl 3-(3-iodopropyl)azetidine-1-carboxylate is an effective PROTAC linker designed for synthesizing Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the degradation of specific proteins by promoting the recruitment of E3 ligases, providing a powerful tool for targeted protein modulation in biological research. It is applicable in studies focused on targeted protein degradation and can aid in the exploration of therapeutic strategies in various disease contexts. -
PROTAC Linker
Methyl 8-oxooctanoate is a versatile PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). It plays a crucial role in the development of novel therapeutic agents by linking target proteins to E3 ligases, thus promoting ubiquitination and degradation. This compound is essential for researchers investigating targeted protein degradation and its implications in various diseases. -
PROTAC Linker
5-Iodopentan-1-ol is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in creating potent and selective modulators of protein function by enabling the targeted degradation of specific proteins. It is essential for researchers focused on developing innovative therapeutic strategies in the fields of drug discovery and protein engineering. -
PROTAC Linker
4-Chlorobutyronitrile is a reactive PROTAC linker utilized in the synthesis of proteolysis-targeting chimera (PROTAC) molecules. It facilitates the assembly of bifunctional small molecules designed to selectively degrade target proteins through the ubiquitin-proteasome system. This compound is valuable in the development of targeted protein degradation strategies for various therapeutic applications, including cancer research and neurological disorders. -
PROTAC Linker
Piperidin-4-amine-C5-O-C1 is a PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It serves as a critical component in the development of bifunctional molecules designed to selectively degrade target proteins via the ubiquitin-proteasome system. This compound enables researchers to explore innovative therapeutic strategies in targeted protein degradation, advancing the field of molecular biology and drug discovery. -
PROTAC Linker
3-(Azetidin-3-yl)propan-1-ol serves as a critical PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound contributes to the selective degradation of target proteins via the ubiquitin-proteasome system. It is utilized in various research applications focused on targeted protein degradation, advancing the understanding of protein function and therapeutic intervention in diseases. -
PROTAC Linker
H2N-PEG4-Hydrazide is a PEG-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing target degradation through the ubiquitin-proteasome system. H2N-PEG4-Hydrazide is essential for researchers exploring targeted protein degradation approaches in drug discovery and development. -
PROTAC Linker
3-(Methylamino)propanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structure is optimized for conjugation, enhancing the efficacy of bioconjugates in research applications focused on protein modulation and cellular control mechanisms. This compound is instrumental in advancing drug discovery efforts aimed at novel therapeutic strategies. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-NHS ester is a PROTAC linker featuring an E3 ligase ligand connected by a PEG4 spacer, enhancing PROTAC drug discovery and development. Its NHS ester functionality allows for efficient coupling with amine-containing molecules, facilitating the formation of targeted protein degradation complexes. The PEG4 spacer further improves the solubility of the conjugated compounds, making this linker a valuable tool in chemical biology research and therapeutic applications. -
PROTAC Linker
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid serves as a versatile PROTAC linker, facilitating the construction of targeted protein degraders. This compound enables the formation of bifunctional molecules that can selectively recruit E3 ligases to target proteins for ubiquitination and subsequent degradation. Its application is pivotal in the development of innovative therapeutics aimed at modulating protein levels and investigating cellular pathways. -
PROTAC Linker
4,4'-(Hexane-1,6-diylbis(oxy))dibenzonitrile serves as a PROTAC linker in the assembly of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of protein ligands, enhancing selective protein degradation in targeted therapeutic applications. Its structural properties make it suitable for the development of innovative treatments in cancer and other diseases. -
PROTAC Linker
Bn-PEG8-OBn is a polyethylene glycol (PEG) linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This versatile linker facilitates the conjugation of target proteins to E3 ligases, enabling selective degradation of proteins of interest. Its application is significant in small molecule drug discovery and biological research, particularly in the development of targeted therapies. -
PROTAC Linker
tert-Butyl 2-(piperidin-4-yl)acetate hydrochloride is a versatile PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to target proteins, enabling targeted degradation pathways. Its role in PROTAC development makes it essential for research applications in targeted protein modulation and therapeutic interventions. -
PROTAC Linker
OH-PEG3-Cl is a bifunctional linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This reagent facilitates the conjugation of target proteins to an E3 ligase, enabling the degradation of specific proteins through the ubiquitin-proteasome system. Its application is crucial in chemical biology for the development of targeted protein degradation strategies that can be used in therapeutic research and drug discovery. -
PROTAC Linker
Ethyl 7-oxoheptanoate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enhancing the degradation of specific target proteins through the recruitment of E3 ligases. Its application extends to research in targeted protein degradation, making it valuable for studies in cancer biology and other disease mechanisms. -
PROTAC Linker
1-Bromo-4-(4-bromobutyl)benzene acts as an effective PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enables the selective degradation of target proteins by bridging an E3 ligase and a protein of interest, thereby enhancing the efficiency of targeted protein degradation studies. Its utility in the development of novel therapeutic strategies makes it valuable for research in drug discovery and protein regulation. -
PROTAC Linker
3-Cyanocyclobutane-1-carboxylic acid serves as a synthetic linker for PROTAC (proteolysis-targeting chimera) development. This compound facilitates the formation of stable PROTACs, enabling targeted protein degradation by linking a target protein ligand to an E3 ligase ligand. Its unique structural properties make it valuable for research applications in protein modulation and therapeutics. -
PROTAC Linker
Ethyl hex-5-ynoate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is crucial for researchers aiming to create novel protein degraders that target specific proteins for degradation in cellular systems. Its versatility and effectiveness make it a valuable tool in chemical biology and drug discovery applications. -
PROTAC Linker
tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine-1-carboxylate is a specialized linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of specific proteins by bridging E3 ubiquitin ligases with the target protein, enhancing the recruitment and subsequent ubiquitination. It is valuable in research applications focused on protein regulation and therapeutic discovery, particularly in cancer and neurodegenerative diseases. -
PROTAC Linkers
HO-PEG8-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of ligand molecules, enhancing the stability and solubility of PROTACs. HO-PEG8-CH2COOH is essential in chemical biology studies aimed at targeted protein degradation and provides a versatile tool for researchers developing novel therapeutic agents. -
PROTAC Linker
2-Propargyl-(trans)-4-cyclohexanediamine functions as a versatile PROTAC linker, enabling the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins through the recruitment of E3 ubiquitin ligases, thereby enhancing the modulation of biological pathways. It is an essential tool in drug discovery and protein regulation research applications. -
PROTAC Linker
3-Hydroxy-2,2,4,4-tetramethylcyclobutan-1-one oxime serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. It enables the efficient combination of target proteins with E3 ligases, enhancing the design of PROTAC molecules. This compound is pivotal in biochemical research focused on modulating protein levels and exploring therapeutic potentials in various diseases. -
PROTAC Linker
Hydroxy-PEG5-C1-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a hydroxy functional group and a Boc protecting group, facilitating conjugation between a target protein ligand and an E3 ligase recruiter. Its application in chemical biology allows for the effective modulation of protein degradation pathways, making it a valuable tool for drug discovery and development. -
PROTAC Linkers
Bromo-PEG5-bromide is a polyethylene glycol (PEG)-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is essential for creating specific targeted therapies by enabling the recruitment of E3 ubiquitin ligases to ubiquitinate and subsequently degrade target proteins. Its unique structure enhances solubility and promotes efficient drug conjugation, making it valuable in the development of innovative therapeutic strategies in chemical biology and drug discovery. -
PROTAC Linkers
m-PEG5-NH2 is a polyethylene glycol (PEG) based linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound features an amino group that facilitates the conjugation of target molecules, enhancing the specificity and efficacy of protein degradation. m-PEG5-NH2 is essential for the development of novel PROTACs in drug discovery and therapeutic applications, enabling targeted modulation of protein levels in various biological systems. -
PROTAC Linkers
m-PEG4-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide functional group, it is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. This reagent is valuable for enhancing target specificity and efficacy in pharmacological research applications. -
PROTAC Linker
Diazo Biotin-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing entities. Its utility in linking biomolecules makes it a valuable tool in targeted protein degradation research and other applications involving the conjugation of proteins or small molecules. -
PROTAC Linker
9-Hydroxynonanoic acid serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the cellular degradation of specific target proteins by linking E3 ligases to the protein of interest. Its application is crucial in chemical biology research aimed at developing targeted protein degraders for therapeutic interventions. -
PROTAC Linker
16-Bromo-1-hexadecanol serves as a PROTAC linker facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Its chemical structure enables efficient conjugation to target proteins, promoting selective degradation pathways. This compound is valuable in research focused on targeted protein degradation and therapeutic innovation in cancer and other diseases. -
PROTAC Linker
3-(3-Aminopropoxy)propan-1-ol is a key PROTAC linker utilized in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the efficient conjugation of target proteins to E3 ligases, enabling selective degradation of specific proteins within cellular systems. It plays a critical role in research applications focused on targeted protein degradation and therapeutic development. -
PROTAC Linker
2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate serves as a key PROTAC linker, facilitating the development of targeted protein degradation constructs. This compound enables the selective recruitment of E3 ubiquitin ligases to target proteins, thereby enhancing the efficiency of PROTACs in biological research. It is instrumental in studies focused on targeted therapy, allowing researchers to explore novel approaches in drug discovery and development. -
PROTAC Linker
(1-Boc-4-piperidinyloxy)acetic acid functions as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). It serves as a crucial component in the synthesis of these bifunctional molecules, enhancing targeted protein degradation in cellular systems. This compound is particularly valuable for research applications involving targeted therapy and protein modulation. -
PROTAC Linker
Benzyl N-(2-aminoethyl)carbamate hydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting E3 ligases to target proteins, enabling targeted degradation of specific cellular proteins. Its application in chemical biology supports research in targeted protein degradation and the exploration of novel therapeutic strategies. -
PROTAC Linker
Potassium (2-benzyloxyethyl)trifluoroborate functions as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is integral to the development of innovative therapeutic strategies that selectively degrade target proteins through the ubiquitin-proteasome system. Its ability to enhance target specificity and efficacy makes it a valuable reagent for researchers in drug discovery and protein biology. -
PROTAC Linker
1-Bromo-4-(3-bromopropyl)benzene serves as a crucial linker in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the development of novel targeted degradation therapies by enabling the conjugation of target proteins to E3 ubiquitin ligases. Its application is significant in research focused on elucidating cellular mechanisms and exploring therapeutic strategies for various diseases, including cancer. -
PROTAC Linker
16-Methoxy-16-oxohexadecanoic acid is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure allows for efficient conjugation to target proteins, enabling selective degradation pathways. This reagent is essential for research applications focused on exploring targeted protein degradation mechanisms and developing novel therapeutics. -
PROTAC Linker
Boc-piperidin-C-COOH is a versatile PROTAC linker that facilitates the development of targeted protein degradation molecules. By serving as a bridge between an E3 ligase ligand and a protein target, it enhances the specificity and efficacy of PROTACs. This compound is essential for researchers aiming to explore protein modulation and degradation pathways in cellular studies. -
PROTAC Linker
1-Bromo-3-(3-bromopropoxy)propane is a versatile PROTAC linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the formation of bifunctional molecules that recruit E3 ligases for targeted protein degradation. Its unique structure allows for optimized interaction with specific biological targets, making it invaluable for research in drug discovery and therapeutic development. -
PROTAC Linker
3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride serves as a PROTAC linker, facilitating the development of heterobifunctional molecules for targeted protein degradation. This compound plays a critical role in the synthesis of PROTACs, enabling the selective modulation of protein activity within cellular pathways. Its unique structural properties make it a valuable tool in chemical biology and therapeutic research applications aimed at degrading specific proteins associated with various diseases. -
PROTAC Linkers
Thiol-PEG8-alcohol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a thiol group, facilitating conjugation to target proteins while enhancing solubility and stability. Its application is essential in the development of novel therapeutic agents that induce targeted degradation of specific proteins, thus enabling innovative strategies in cellular biology and drug discovery. -
PROTAC Linker
1,18-Dibromooctadecane serves as a PROTAC linker, facilitating the development of targeted protein degradation agents. Its unique structure allows for the effective conjugation of protein-targeting moieties with E3 ligase ligands, enhancing the specificity and efficacy of PROTAC compounds. This linker is instrumental in advancing research focused on proteolysis-targeting chimeras and their therapeutic applications in various diseases. -
PROTAC Linker
3-(4-Bromophenyl)propan-1-ol serves as an effective PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by linking E3 ligases to the desired protein of interest, thereby enhancing the efficiency of targeted protein modulation in research settings. Its utility in PROTAC development supports investigations into protein interactions, degradation pathways, and therapeutic approaches in various disease models.
