Fig. 1 · Structure
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mPEG45-diol
PROTAC Link
mPEG45-diol is a polyether-based PEG derivative designed as a linker for PROTAC (Proteolysis Targeting Chimera) synthesis. Its functional properties facilitate the conjugation of small molecules to E3 ligases, enabling targeted degradation of specific protein targets within cellular systems. This compound is vital for optimizing the design and efficacy of PROTAC molecules in cellular and molecular biology research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 122202-39-5 |
| Applications | PROTAC Link |
| Formula | C94H190O48 |
| Molecular Weight | 2088.49 |
| SMILES | COCCOCC(CO)O.[45] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.