Fig. 1 · Structure
Documents & Downloads
Biotin-PEG11-amine
PROTAC Linker
Biotin-PEG11-amine is a biotinylated polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the selective degradation of target proteins by connecting an E3 ligase to a protein of interest, thereby enhancing cellular degradation pathways. Its application in PROTAC development makes it a valuable tool for investigating protein regulation and therapeutic interventions in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1418022-42-0 |
| Applications | PROTAC Linker |
| Formula | C34H66N4O13S |
| Molecular Weight | 770.97 |
| SMILES | O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.