Mal-PEG4-OH

Catalog No.: A81674
PROTAC Linker
Mal-PEG4-OH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the connection between the target protein and an E3 ligase, thereby promoting ubiquitination and subsequent degradation of the target protein. Mal-PEG4-OH is essential for researchers developing targeted protein degradation strategies in various therapeutic applications, enabling enhanced specificity and efficacy in protein modulation studies.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$45.00
In stock
100mg
$140.00
In stock
250mg
$180.00
In stock
500mg
$305.00
In stock
1g
$490.00
In stock
5g
$1,335.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PEG4-OH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the connection between the target protein and an E3 ligase, thereby promoting ubiquitination and subsequent degradation of the target protein. Mal-PEG4-OH is essential for researchers developing targeted protein degradation strategies in various therapeutic applications, enabling enhanced specificity and efficacy in protein modulation studies.
Product Information
Catalog NumA81674
FormulaC12H19NO6
Molecular Weight273.28
CAS Number1421933-37-0
SMILESO=C(C=C1)N(CCOCCOCCOCCO)C1=O
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