Fig. 1 · Structure
Documents & Downloads
Azido-PEG5-azide
PROTAC Linkers
Azido-PEG5-azide is a PEG-based linker specifically designed for PROTAC synthesis, targeting the interaction of protein degradation pathways. This compound features an azide functional group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the conjugation to alkyne-modified molecules or those containing DBCO or BCN groups. Its versatility in click chemistry applications makes it a valuable tool in the development of bifunctional PROTACs for targeted protein degradation studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 356046-26-9 |
| Applications | PROTAC Linkers |
| Formula | C12H24N6O5 |
| Molecular Weight | 332.36 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.