Fig. 1 · Structure
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Pentaethylene glycol monomethyl ether
PROTAC Linker
Pentaethylene glycol monomethyl ether is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimera) molecules. This compound plays a crucial role in the formation of PROTACs, facilitating targeted degradation of specific proteins through the ubiquitin-proteasome system. Its application in chemical biology enables researchers to explore new avenues for therapeutic interventions by harnessing the power of protein modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23778-52-1 |
| Applications | PROTAC Linker |
| Formula | C11H24O6 |
| Molecular Weight | 252.30 |
| SMILES | COCCOCCOCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.