Fig. 1 · Structure
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4-Bromobutan-1-amine hydrobromide
PROTAC Linker
4-Bromobutan-1-amine hydrobromide serves as a versatile linker in the development of PROTAC (proteolysis-targeting chimeras) molecules. This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, enabling targeted protein degradation, a crucial mechanism in cellular regulation and therapeutic intervention. Its application is significant in drug discovery and development, particularly in the fields of cancer research and targeted therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 24566-81-2 |
| Applications | PROTAC Linker |
| Formula | C4H11Br2N |
| Molecular Weight | 232.95 |
| SMILES | Br.BrCCCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.