Name: Oxocarbazate
Brand: Adooq Bioscience
SKU: A22503
Rating: 5 (288 reviews)

Catalog No.

Product Name

Application

Product Information

Citations

A11265

Odanacatib (MK-0822)

Cathepsin K Inhibitor

Odanacatib is an inhibitor of cathepsin K,an enzyme involved in bone resorption.

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A11466

Cathepsin Inhibitor 1

Cathepsin Inhibitor

Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.

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A12020

Balicatib

Cathepsin K inhibitor

Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys.

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A12487

L-873724

Cathepsin K inhibitor

L-873724 is a potent, orally bioavailable, selective and reversible non-basic cathepsin K inhibitor.

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A13256

CA-074

Cathepsin B inhibitor

CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM.
- Tianming Qiu, .et al. , Cell Death Dis, 2018, Oct; 9(10): 946 PMID: 30237538
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A13394

Petesicatib

cathepsin S inhibitor

Petesicatib is a cathepsin S inhibitor, used in research of immune diseases.

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A13502

Z-FL-COCHO (LY3000328)

Cathepsin S inhibitor

Z-FL-COCHO (LY3000328) is a novel Cathepsin S inhibitor.
- Gil-Im Mun, .et al. , Biochim Biophys Acta Mol Basis Dis, 2024, Sep 25;1871(1):167523 PMID: 39332782
- Fu R, .et al. , Sci Rep, 2020, Jan 29;10(1):1455 PMID: 31996771
- Klinngam W, .et al. , Sci Rep, 2019, Jul 2;9(1):9559 PMID: 31267034
- Chen CY, .et al. , Clin Sci (Lond), 2018, Oct 29;132(20):2221-2239 PMID: 30287519
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A13593

CA-074 Methyl Ester

Cathepsin B inhibitor

CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.
- Qian Chu, .et al. , Food Chem Toxicol, 2021, Jan;147:111867 PMID: 33217525
- Ye Tao, .et al. , Chemosphere, 2020, Mar;242:124959 PMID: 31669990
- Ming Sun, .et al. , J Agric Food Chem, 2018, Nov 21;66(46):12376-12384 PMID: 30392375
- Xueyan Wu, .et al. , Food Chem Toxicol, 2017, Aug;106(Pt A):273-282 PMID: 28579546
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A15302

L 006235

Cathepsin K Inhibitor

L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S.

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A15313

SID 26681509

Human cathepsin L inhibitor

SID 26681509 is a reversible and potent human cathepsin L inhibitor. SID 26681509 displays no inhibitory activity of cathepsin G.

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A15685

LY3000328

Cathepsin S inhibitor

LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases.

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A20122

MIV-247

Cathepsin S inhibitor

MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively.

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A21069

VBY-825

cathepsin inhibitor

VBY-825 is a novel, reversible cathepsin inhibitor with high potency against cathepsins B, L, S and V.
- Laura Odongo, .et al. , Microbiol Spectr, 2023, Sep 20;11(5):e0190823 PMID: 37728342
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A21558

MK-0674

cathepsin K inhibitor

MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S.

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A22503

Oxocarbazate

human cathepsin L inhibitor

Oxocarbazate, also known as CID23631927, is an inhibitor of human cathepsin L.

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Cathepsin