Fig. 1 · Structure

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Cathepsin K inhibitor 3

Cat. No. A39851 CAS 1694638-70-4

Cathepsin K Inhibitor

Cathepsin K Inhibitor 3 is a highly selective inhibitor targeting cathepsin K, demonstrating an IC50 value of 0.5 nM. This compound exhibits a favorable pharmacokinetic profile, making it suitable for research applications in osteoarthritis studies. Its specific action on cathepsin K positions it as a valuable tool in elucidating the role of this enzyme in bone resorption and related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1694638-70-4
Applications Cathepsin K Inhibitor
Formula C30H31FN4O4S
Molecular Weight 562.65
SMILES
O=S1(CCN(CC1)C2=CC=C(C3=C([C@@H]4CCCC[C@H]4C(NC5(CC5)C#N)=O)OC(C6=CC=C(C=C6)F)=N3)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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