Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
16α-Hydroxyestrone (16αOHE) is an endogenous metabolite of Estradiol, primarily involved in estrogen metabolism. This compound serves as a valuable tool for investigating metabolic diseases and their relationship with hormonal regulation. Its biological activity offers insights into the role of estrogen metabolites in health and disease, making it significant for research in endocrinology and metabolic pathways. -
Endogenous Metabolite
Allantoic acid, an endogenous metabolite, is a degradation product of uric acid linked to purine metabolism. It plays a significant role in various biological processes, including nitrogen metabolism and cellular detoxification. Research applications involve studying metabolic pathways and assessing physiological functions related to purine degradation in both physiological and pathological conditions. -
Endogenous Metabolite
3-Methyl-2-oxovaleric acid sodium is an endogenous metabolite derived from the degradation of isoleucine. This compound serves as a biomarker for mustard airway diseases (MADs) and is implicated in uric acid stone formation. Its assessment can facilitate research in metabolic disorders and pulmonary health. -
Endogenous Metabolite
Erythrodiol is an endogenous metabolite found in olive oil that targets the ABCA1 protein. It promotes cholesterol efflux by selectively inhibiting the degradation of this protein, thereby enhancing lipid homeostasis. Erythrodiol is a promising candidate for further investigation in therapeutic or preventive applications related to atherosclerosis and cardiovascular health. -
Endogenous Metabolite
2'-Deoxyinosine is an endogenous metabolite with implications in purine metabolism. It has been shown to inhibit the growth of human colon carcinoma cell lines, highlighting its potential role in cancer research. Additionally, it is associated with purine nucleoside phosphorylase (PNP) deficiency, making it a valuable compound for studying metabolic disorders and therapeutic interventions in oncology. -
Endogenous Metabolite
5-Hydroxymethyl-2-furancarboxylic acid is an endogenous metabolite derived from 5-hydroxymethyl-2-furfural (HMF). This compound plays a crucial role in metabolic pathways and is primarily excreted through renal processes. It serves as a valuable biomarker for studying oxidative stress and its implications in various biological systems, contributing to research on metabolic disorders and environmental impacts on health. -
Endogenous Metabolite
3-O-Methyl-DL-DOPA is an endogenous metabolite that serves as a key biomarker in cerebrospinal fluid. This compound is utilized in research focused on neurological disorders, including epilepsy, purine nucleoside phosphorylase deficiency, and aromatic L-amino acid decarboxylase deficiency. Its role in metabolic pathways makes it valuable for investigating disease mechanisms and potential therapeutic strategies. -
Endogenous Metabolite
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an endogenous metabolite known for its role as an orally active omega-3 fatty acid agent. It enhances liver β-oxidase activity and decreases total triglyceride levels in the liver while increasing triglyceride and phospholipid omega-3 content. This compound is valuable in research applications focused on lipid metabolism and the effects of omega-3 fatty acids on liver function. -
Endogenous Metabolite
N-Acetyl-L-histidine monohydrate is an endogenous metabolite derived from histidine. It plays a significant role in various biological processes, particularly within the brain, retina, and lens of poikilothermic vertebrates. This compound is useful for research applications focused on metabolic pathways and neurobiological studies. -
Endogenous Metabolite
Cis-9,10-Epoxystearic acid is an endogenous metabolite with significant presence in plasma and urine. This compound is involved in various biological processes and can serve as a valuable marker for metabolic studies. Its applications include research into lipid metabolism and the investigation of epoxide-mediated cellular mechanisms. -
Endogenous Metabolite
D-(-)-Lactic acid sodium is an endogenous metabolite that plays a critical role in various metabolic processes. It primarily functions as a product of anaerobic glycolysis, contributing to energy production and acid-base balance in biological systems. This compound is valuable for research applications involving metabolic studies, cell culture, and investigations into lactic acidosis. -
Endogenous Metabolite
Cyclo(Ala-Gly) is an endogenous metabolite known for its cytotoxic effects on cancer cell lines, specifically A549, HepG2, and HT29. With IC50 values ranging from 9.5 to 18.1 μM, this compound serves as a valuable tool in cancer research, aiding in the investigation of potential therapeutic strategies and metabolic pathways linked to tumor cell viability. -
Endogenous Metabolite
3α,12β-Dihydroxycholanoic acid is an endogenous metabolite categorized as a bile acid, primarily found in human urine. It plays a crucial role in the regulation of lipid metabolism and is utilized in research to study the physiological effects of bile acids on metabolic pathways. This compound's analysis can aid in understanding the implications of bile acids in various health conditions and disease states. -
Endogenous Metabolite
3-Ethoxy-3-oxopropanoic acid is an endogenous metabolite known for its role in promoting plant growth. This compound can be utilized in research applications aimed at understanding the biochemical pathways involved in plant development and metabolism. Its involvement in growth regulation makes it a valuable reagent for studies focused on agricultural science and plant physiology. -
Endogenous Metabolite
N1,N8-Diacetylspermidine is an endogenous metabolite and a derivative of polyamines found in human urine. It has been identified as a potential prognostic indicator for cancer patients, providing valuable insights during treatment and follow-up examinations. Its relevance in cancer research positions it as a significant biomarker for monitoring disease progression and therapeutic response. -
Endogenous Metabolite
4-Ethylphenol is a volatile phenolic compound recognized for its association with undesirable odors in wine, serving as an endogenous metabolite. Synthesized by intestinal flora, 4-Ethylphenol is converted into 4-ethylphenyl sulfate through the action of Lactobacillus plantarum. This compound is of interest in the study of aromatic profiles in fermented products and microbial metabolism in the gastrointestinal tract. -
Endogenous Metabolite
α-D-Glucose-1-phosphate disodium is an endogenous metabolite that serves as a key starting material for the synthesis of glucuronic acid. This compound exhibits cytostatic properties, making it relevant in cardiopathic therapy, while also demonstrating antibiotic and immunosuppressive activities. Its applications extend to the therapeutic support of the circulatory system, highlighting its versatility in biochemical research and therapeutic development. -
Endogenous Metabolite
Trihydroxycholestanoic acid is an endogenous metabolite that plays a crucial role in lipid metabolism. This compound is relevant for research into metabolic disorders, including Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency, and Infantile Refsum Disease. Its study may provide insights into the pathophysiology and therapeutic approaches for these genetic conditions. -
Endogenous Metabolite
Zaragozic acid A is a reversible competitive inhibitor of squalene synthase, acting as an endogenous metabolite. This compound effectively inhibits acute hepatic cholesterol synthesis in mouse models, with an IC50 value of 6 μM. Its application is significant in studies investigating cholesterol metabolism and the regulation of lipid biosynthesis. -
Endogenous Metabolite
Leukotriene C4 is an endogenous metabolite and an eicosanoid lipid mediator involved in type 2 inflammatory responses. This compound plays a significant role in mediating various biological activities such as inflammation, allergic reactions, bronchoconstriction, and increased vascular permeability. It is commonly used in research applications to study pathways related to asthma, allergic inflammation, and other related disorders. -
Endogenous Metabolite
5-Phenylvaleric acid is an endogenous metabolite primarily produced by gut microbiota through the metabolism of flavan-3-ols. This compound serves as a valuable biomarker for assessing flavan-3-ol intake in dietary studies. In addition, 5-Phenylvaleric acid can be utilized as a precursor for the synthesis of polyhydroxyalkanoates, making it relevant for research in biopolymers and sustainable materials. -
Endogenous Metabolite
Taurohyocholic acid sodium salt is a taurine-conjugated hyocholic acid that acts as an endogenous metabolite. It serves as a predictor of the efficacy of tyrosine kinase inhibitors in combination with PD-1 inhibitors for the treatment of hepatocellular carcinoma (HCC). This compound is particularly valuable for researchers investigating metabolic profiles and treatment responses in liver cancer models. -
Endogenous Metabolite
2-Methylsuccinic acid is an endogenous metabolite that plays a significant role in various metabolic pathways. Its presence serves as a key biochemical marker in conditions such as ethylmalonic encephalopathy. This compound is useful for researching metabolic disorders and investigating biochemical processes in human fluids. -
Endogenous Metabolite
Succinyladenosine is a key endogenous metabolite formed through the dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase. This compound serves as an important biochemical marker for adenylosuccinase (ASL) deficiency, facilitating research into metabolic disorders. Its role in cellular metabolism positions it as a valuable tool for studying nucleotide metabolism and related pathophysiological conditions. -
Endogenous Metabolite
Lysophosphatidylethanolamines (LPE) are endogenous lysophospholipids generated through the deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). LPE is known to enhance ERK1/2 phosphorylation in PC12 cells, an effect that can be attenuated by MEK inhibitors such as U-0126 and PD 98059, as well as the EGFR inhibitor AG-1478. Additionally, LPE promotes neurite outgrowth and increases neurofilament M expression in these cells. This product encompasses various molecular species of lysophosphatidylethanolamine characterized by differing fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position, making it suitable for diverse biological research applications. -
Endogenous Metabolite
(2-Aminoethyl)phosphonic acid is an endogenous metabolite and amino acid analog, primarily involved in cellular metabolic processes. This compound plays a significant role in the synthesis of biological macromolecules and is utilized in the preparation of hydrogels for various research applications, including tissue engineering and drug delivery systems. Its unique properties make it a valuable tool for studying biochemical pathways and material science. -
Endogenous Metabolite
Acetic acid-13C2 is a stable isotope-labeled analogue of acetic acid, primarily utilized for tracking metabolic processes. It serves as a biomarker in biochemical research, facilitating the analysis of various metabolic pathways. Furthermore, Acetic acid-13C2 is valuable in medical imaging and compound development, enhancing comprehension of biological mechanisms and interactions. -
Endogenous Metabolite
Cholesteryl palmitate is a key endogenous metabolite and a prominent cholesterol ester found in human blepharitis. It plays a crucial role in forming a stable tear film, making it an important subject for studying amphiphilic block copolymers as potential surfactants in dry eye syndrome research. Additionally, cholesteryl palmitate serves as a valuable predictor of fetal lung maturity and as a prognostic biomarker in the assessment of chronic interstitial pneumonia. -
Endogenous Metabolite
2-Furoylglycine is an endogenous metabolite primarily associated with coffee consumption. It serves as a potential biomarker for dietary studies and can be utilized in research investigating the metabolic effects of coffee intake on human health. Its presence in urine can provide insights into individual coffee consumption patterns and associated metabolic processes. -
Endogenous Metabolite
Methionine sulfoximine is an irreversible inhibitor of glutamine synthetase, impacting the metabolism of glutamate and glutamine. Its unique properties make it valuable for neurobiological research, particularly in the study of epilepsy and related mechanisms. Investigating its convulsive effects aids in understanding the underlying biochemical pathways involved in neurological conditions. -
Endogenous Metabolite
Pyridoxylamine acts as an inhibitor of advanced glycation end products (AGEs) and lipoxidation end products (ALEs). This compound demonstrates protective effects against diabetes-induced retinal vascular lesions, making it valuable in diabetes research. Pyridoxylamine serves as a critical tool for studying the mechanisms underlying diabetic complications and may provide insights into therapeutic strategies for managing such conditions. -
Endogenous Metabolite
Tetradecanedioic acid is an endogenous metabolite classified as a long-chain fatty acid. It serves as a valuable biomarker for evaluating the activity of organic anion transporting polypeptides (OATPs). Its role in metabolic studies makes it an important reagent for research applications focused on lipid metabolism and transport mechanisms. -
Endogenous Metabolite
D-Glucose 6-phosphate sodium acts as a critical endogenous metabolite involved in key biochemical pathways, including glycolysis and the pentose phosphate pathway. This compound serves as a primary substrate for various enzymatic reactions and plays an essential role in cellular energy metabolism and regulation. D-Glucose 6-phosphate sodium is widely utilized in research applications focusing on metabolism, enzymology, and cellular signaling pathways. -
Endogenous Metabolite
N-Isovaleroylglycine is an acyl glycine that serves as an endogenous metabolite involved in energy metabolism. It has been identified as a potential biomarker for predisposition to weight gain and obesity. This compound is useful in research focused on metabolic disorders, weight regulation, and related physiological processes. -
Endogenous Metabolite
2-Hydroxy-2-methylbutanoic acid is an endogenous metabolite linked to metabolic disorders such as 2-hydroxyglutaric aciduria and maple syrup urine disease. This compound is important for studying metabolic pathways and the impact of abnormal metabolite accumulation on cellular function. It serves as a valuable tool for researchers investigating these conditions and their underlying mechanisms. -
Endogenous Metabolite
Salicyluric acid is an endogenous metabolite resulting from the conjugation of salicylic acid. It plays a significant role in pharmacokinetics, influencing the metabolism and excretion of salicylate medications. Research applications include studies on drug metabolism, the physiological effects of salicylic acid, and the exploration of its potential impact on inflammatory processes. -
Endogenous Metabolite
trans-Zeatinriboside is a naturally occurring cytokinin precursor that serves as a key signaling molecule in xylem vessels. It plays a significant role in regulating leaf size and meristem activity, influencing plant growth and development. This metabolite is essential for studies on plant physiology and responses to environmental stimuli. -
Endogenous Metabolite
m-Anisaldehyde (3-Methoxybenzaldehyde) targets the regulation of thyroid autoimmunity and serves as an endogenous metabolite. This compound is implicated in biochemical pathways relevant to thyroid function, particularly during early pregnancy. Its examination may contribute to a better understanding of metabolic changes and autoimmunity in reproductive health research. -
Endogenous Metabolite
Perillartine is an endogenous metabolite that functions as a natural sweetener by activating the taste receptor type 1 member 2 (Tas1r2) subunit, exhibiting species-dependent selectivity. Its unique interaction with taste receptors makes it valuable for research in sensory biology and taste perception. Perillartine can be utilized in studies to explore the mechanisms of sweet taste transduction and to evaluate potential applications in food science and health-related fields. -
Endogenous Metabolite
DL-Tryptophan is an endogenous metabolite that serves as a precursor to several important biomolecules, including serotonin and melatonin. It plays a crucial role in neurotransmitter regulation and affects mood, sleep, and overall brain function. This compound is widely used in research applications focused on metabolic pathways, neurobiology, and psychiatric disorders, facilitating insights into the biochemical mechanisms underlying behavioral and physiological processes. -
Endogenous Metabolite
6-keto Prostaglandin F1α is an endogenous metabolite involved in various physiological processes. It plays a significant role in the regulation of inflammation and vascular function, making it valuable in research related to conditions such as meningitis, rheumatoid arthritis, and cardiopulmonary resuscitation. This compound can be detected in cerebrospinal fluid, urine, and blood, facilitating its application in biochemical studies and diagnostics. -
Endogenous Metabolite
7,12-Diketolithocholic acid is an endogenous metabolite derived from the co-metabolism of bile acids by host gut microbiota. This bile acid plays a role in the regulation of lipid metabolism and may influence gut homeostasis. It is useful for studying bile acid metabolism, microbiome interactions, and their effects on metabolic disorders. -
Endogenous Metabolite
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine is an endogenous metabolite that plays a role in membrane biology. It is relevant for studying physiological processes associated with pregnancy and various pathological states such as sepsis. This compound can facilitate investigations into lipid metabolism and cellular signaling pathways in related biological contexts. -
Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a crucial deoxynucleotide building block of DNA. It serves as a substrate for UMP/CMP kinase, converting to dCDP through phosphorylation to dCTP, thereby supporting DNA biosynthesis. This compound is vital for research applications involving nucleic acid synthesis and cellular metabolism studies. -
Endogenous Metabolite
Isobutyryl-L-carnitine chloride is an endogenous metabolite that plays a role in fatty acid metabolism. It functions as an acylated form of carnitine, facilitating the transport of fatty acids into the mitochondria for β-oxidation. This compound is valuable in research applications related to metabolic disorders, mitochondrial function, and energy metabolism studies. -
Endogenous Metabolite
Cholesteryl arachidonate is an endogenous metabolite that serves as a precursor in various biological signaling pathways. It is known for its role in membrane lipid signaling, influencing cellular responses and inflammation. This compound is utilized in research applications studying lipid metabolism, cellular signaling mechanisms, and the interplay between cholesterol and fatty acids. -
Endogenous Metabolite
Indole-3-methanamine is an endogenous metabolite primarily linked to dietary intake of cereals and grain products. It has been identified as a potential biomarker for monitoring the consumption of foods like barley and other cereals. This compound is relevant in nutritional research and metabolic studies, providing insights into dietary patterns and health outcomes. -
Endogenous Metabolite
Pyrimidine, a nitrogen-containing heterocyclic compound, serves as an endogenous metabolite with significant biological relevance. It plays a crucial role in various cellular processes and is utilized in research related to pancreatic cancer, triple-negative breast cancer, colon carcinoma, and neurological studies. Its derivatives can provide insights into disease mechanisms and potential therapeutic interventions. -
Endogenous Metabolite
3-Ethoxy-3-oxopropanoic acid potassium is an endogenous metabolite that serves as a growth promoter in plants. Its primary mechanism involves enhancing physiological processes related to growth and development. This compound is useful in research applications focused on plant biochemistry and environmental stress responses. -
Endogenous Metabolite
1,4-Dioxane-2,5-diol is an endogenous metabolite involved in various biochemical pathways. It serves as a substrate in the biosynthesis of important cellular components and is relevant in studies examining metabolic processes. This compound is utilized in research focusing on metabolic profiling and the exploration of metabolic disorders.
