L-Phenylalanine-13C9,15N is a stable isotope-labeled version of the essential amino acid L-Phenylalanine, featuring carbon-13 and nitrogen-15 isotopes. This compound serves as an α2δ subunit antagonist for voltage-dependent Ca²⁺ channels, exhibiting a Ki of 980 nM. Additionally, L-Phenylalanine acts as a competitive antagonist at the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs), with a KB of 573 μM. Its applications extend to the fields of metabolic studies, tracer studies in amino acid metabolism, and the development of food flavors and pharmaceuticals.
L-Phenylalanine-13C9,15N is a stable isotope-labeled version of the essential amino acid L-Phenylalanine, featuring carbon-13 and nitrogen-15 isotopes. This compound serves as an α2δ subunit antagonist for voltage-dependent Ca²⁺ channels, exhibiting a Ki of 980 nM. Additionally, L-Phenylalanine acts as a competitive antagonist at the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs), with a KB of 573 μM. Its applications extend to the fields of metabolic studies, tracer studies in amino acid metabolism, and the development of food flavors and pharmaceuticals.
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