L-Phenylalanine-d2 is a deuterium-labeled form of the essential amino acid L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid). It serves as a stable isotope and acts as an antagonist of the α2δ subunit of voltage-dependent calcium channels, with a Ki of 980 nM. Additionally, L-Phenylalanine-d2 competitively inhibits glycine- and glutamate-binding sites on both N-methyl-D-aspartate receptors (NMDARs) and non-NMDARs, demonstrating a Ki of 573 μM. This reagent is valuable for applications in biochemical research, including metabolic studies and tracer experiments.
L-Phenylalanine-d2 is a deuterium-labeled form of the essential amino acid L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid). It serves as a stable isotope and acts as an antagonist of the α2δ subunit of voltage-dependent calcium channels, with a Ki of 980 nM. Additionally, L-Phenylalanine-d2 competitively inhibits glycine- and glutamate-binding sites on both N-methyl-D-aspartate receptors (NMDARs) and non-NMDARs, demonstrating a Ki of 573 μM. This reagent is valuable for applications in biochemical research, including metabolic studies and tracer experiments.
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