Fig. 1 · Structure
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Acetylcholine-d4 chloride
Stable Isotope
Acetylcholine-d4 chloride is a deuterium-labeled form of the neurotransmitter acetylcholine. It functions as a potent cholinergic agonist and effectively crosses the blood-brain barrier (BBB). This reagent modulates dopaminergic neuronal activity by stimulating nicotinic acetylcholine receptors (nAChRs) and has also been shown to inhibit the aggregation of p53 mutant peptides in vitro. Its unique isotopic labeling makes it a valuable tool for chemical and biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 344298-94-8 |
| Applications | Stable Isotope |
| Formula | C7H12D4ClNO2 |
| Molecular Weight | 185.69 |
| Synonyms | ACh-d4 chloride |
| SMILES | CC(OC([2H])([2H])C([2H])([2H])[N+](C)(C)C)=O.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.