Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Licoricone is a flavonoid derived from licorice that serves as a bacterial inhibitor. It demonstrates significant anti-Helicobacter pylori activity against both clarithromycin- and amoxicillin-resistant strains, as well as four clarithromycin- and amoxicillin-sensitive strains. This compound is valuable for research focusing on bacterial resistance and studies aimed at developing new therapeutic strategies against H. pylori infections. -
Antibacterial Agent
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent primarily targeting bacterial protein synthesis. Its key biological activity makes it valuable for studying respiratory tract infections and various bacterial pathogens. This compound is instrumental in research applications focused on antibiotic resistance and the development of new antibacterial therapies. -
Bacterial Inhibitor
Nornidulin is a depsidone derived from Aspergillus nidulans, exhibiting significant antibacterial activity against Mycobacterium tuberculosis and Mycobacterium ranoe, as well as antifungal effects against Trichophyton tonsurans and Microsporum audouini. Additionally, it demonstrates potent inhibition of methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. Furthermore, Nornidulin displays cytotoxicity in MOLT-3 cells with an IC50 value of 35.7 μM, while exhibiting lower toxicity against HuCCA-1, HepG2, and A549 cell lines. -
β-lactamase Inhibitor
Brobactam sodium is a potent synthetic β-lactamase inhibitor that effectively targets various β-lactamase enzymes. This compound exhibits broad-spectrum antibacterial activity, making it a valuable tool for enhancing the efficacy of β-lactam antibiotics. Brobactam sodium is primarily utilized in research applications aimed at understanding antibiotic resistance mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibiotic Agent
Cefaloglycin is a nephrotoxic β-lactam cephalosporin antibiotic that exhibits significant antibacterial activity, specifically targeting Gram-positive cocci, excluding enterococci. Its mechanism involves inhibition of bacterial cell wall synthesis, making it effective in clinical settings requiring treatment of specific bacterial infections. Additionally, Cefaloglycin has been shown to interfere with mitochondrial substrate uptake and respiration, adding to its profile as a compound of interest in biochemical and pharmacological research. -
Antibacterial Agent
4-Methoxycoumarin primarily targets bacterial pathogens and exhibits notable antibacterial activity against Ralstonia solanacearum. This compound is useful for research applications focused on the development of antimicrobial agents and further understanding of bacterial resistance mechanisms. Its unique structure may provide insights into the design of novel therapeutics in the fight against bacterial infections. -
Bacterial Inhibitor
3-CPs is a serotype capsular polysaccharide that inhibits antibody-mediated bacterial killing. By interfering with the immune response, it effectively reduces the phagocytosis of encapsulated bacteria. This compound is valuable for studying bacterial pathogenesis and the mechanisms of immune evasion. 3-CPs can inform research on vaccine development and therapeutic strategies aimed at combating encapsulated bacterial infections. -
Heat-inactivated Bacterial Luciferases Inhibitor
2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone-dependent refolding of heat-inactivated bacterial luciferases. By interacting with hydrophobic segments of heat-inactivated substrates, it competes with chaperones such as IbpAB. This compound is valuable for research into bacterial infections and the mechanisms of chaperone-mediated protein refolding. -
Antibiotic
Micrococcin P1 is a macrocyclic peptide antibiotic exhibiting significant antiviral and antibacterial activity. Its primary mechanism involves the inhibition of hepatitis C virus (HCV) replication, with an EC50 range of 0.1-0.5 μM. Additionally, Micrococcin P1 demonstrates in vitro antibacterial efficacy against Gram-positive bacteria, with MIC values of 2 μg/mL for Staphylococcus aureus, 1 μg/mL for Enterococcus faecalis, and 1 μg/mL for Streptococcus pyogenes. Furthermore, it is an effective inhibitor of the malaria parasite Plasmodium falciparum, making it valuable for diverse research applications in infectious diseases. -
Parasite Inhibitor
Hydroxymetronidazole, a metabolite of Metronidazole, functions primarily as an inhibitor of parasitic infections. This nitroimidazole derivative exhibits significant antibacterial and antiprotozoal activities, making it valuable in research applications related to bacterial and protozoal diseases. It is particularly useful for studying conditions such as swine dysentery, as well as genital trichomoniasis in cattle, contributing to a better understanding of these veterinary health issues. -
Antibacterial Agent
Halocarban is an antibacterial agent that targets a range of bacterial strains by disrupting cell membrane integrity. Its primary biological activity includes inhibition of bacterial growth, making it suitable for research in microbiology and potential applications in personal care products. Studies have shown its effectiveness in formulations that aim to combat odor-causing bacteria. -
Antibacterial Agent
Oleanolic aldehyde is an antibacterial agent that targets oral bacteria, specifically inhibiting the growth of Streptococcus mutans and Porphyromonas gingivalis, which are linked to dental caries and periodontal disease. The compound demonstrates minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL against these pathogens, respectively. Oleanolic aldehyde is valuable for research focused on oral health and the development of antibacterial strategies. -
Antibacterial Agent
2-Hydroxy-1-methoxyanthraquinone is an antibacterial agent derived from the stem bark of Morinda lucida Benth. It demonstrates significant antibacterial activity, making it a valuable compound for research involving microbial inhibition and the study of bacterial resistance. This compound is useful in exploring potential therapeutic applications in the field of infectious diseases. -
Bacterial Inhibitor
Ethyl Orsellinate is a lichen-derived metabolite and a derivative of lecanoric acid, primarily acting as a bacterial inhibitor. It exhibits notable antiproliferative and antitumor activities, making it useful in cancer research. The compound demonstrates significant cytotoxicity against A. salina, with an LC50 of 495 μM, indicating its potential as a bioactive agent in the study of microbial and tumor biology. -
Antibacterial Agent
Monascorubrin is an antibacterial agent derived from Monascus mycelia. It exhibits a range of biological activities, including anti-inflammatory, anti-tumor, and immunomodulatory properties. Despite its therapeutic potential, Monascorubrin has been associated with embryotoxicity, exhibiting an ED50 of 4.3 μg in chicken embryos. This compound is valuable for research on tumors and inflammatory diseases, contributing to the understanding of their underlying mechanisms. -
Antibacterial Agent
16-O-Deacetyl fusidic acid lactone is an antibacterial agent derived from fusidic acid, primarily targeting Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it valuable for research applications focused on Gram-positive infections. Additionally, it is ineffective against Gram-negative bacteria, which may influence experimental design in studies relating to bacterial resistance and infection control. -
Bacterial Inhibitor
EcMetAP1-IN-1 is a selective inhibitor of Escherichia coli methionine aminopeptidase 1 (MetAP1), a key enzyme involved in protein maturation. By obstructing the enzymatic activity of MetAP1, this compound effectively disrupts bacterial growth and protein synthesis, making it a valuable tool for research focused on bacterial infections and antibiotic development. Its specificity towards MetAP1 further positions EcMetAP1-IN-1 as a potential candidate for studying the mechanistic roles of methionine aminopeptidases in pathogenic bacteria. -
Bacterial Inhibitor
Urolithin M6 is a polyphenolic compound primarily recognized for its role as a bacterial inhibitor. This metabolite, synthesized through intestinal microbial metabolism, exhibits potential antioxidant properties and may function as an analogue to tannic acid compounds. Urolithin M6's production in humans necessitates the presence of specific bacterial 3-dehydroxylase activity, unveiling a novel pathway for its biotransformation. The metabolic profile of Urolithin M6 can aid in stratifying individuals for research aimed at elucidating its implications in health and disease. -
Bacterial Inhibitor
Methyl octanoate acts as a bacterial inhibitor and is recognized for its role in antimicrobial activity. This compound has applications in food preservation and can be studied for its effects on microbial growth inhibition. Additionally, it serves as a volatile aroma component in various beverages, including persimmon wine, making it of interest in both food science and microbiology research. -
Macrocyclic Lipopeptide Antibiotic
Malacidin B is a macrocyclic lipopeptide antibiotic that exerts its antibacterial effects through a calcium-dependent mechanism. It has demonstrated significant activity against a range of Gram-positive bacteria, making it a valuable tool for researchers studying antibiotic resistance and developing new antimicrobial therapies. Its unique structure and mechanism of action provide avenues for exploring novel treatments in bacterial infections. -
Antibiotic
M 14659 is a semisynthetic cephalosporin antibiotic with potent antimicrobial activity. It exhibits strong inhibitory effects against Gram-negative bacteria, notably Pseudomonas aeruginosa. This compound is applicable in research focused on antibiotic resistance and the development of novel therapeutic strategies for bacterial infections. -
Antibiotic
Cefpodoxime proxetil impurity B is a key impurity associated with Cefpodoxime proxetil, a third-generation cephalosporin antibiotic. This compound exhibits antibacterial activity, primarily targeting bacterial cell wall synthesis. It serves as an important reference standard in pharmaceutical research and development for quality control and analytical studies evaluating the purity of Cefpodoxime proxetil formulations. -
Antibiotic
Erythromycin gluceptate is a macrolide antibiotic that targets bacterial 50S ribosomal subunits, inhibiting RNA-dependent protein synthesis through the blockade of transpeptidation and translocation reactions. Its broad spectrum of antimicrobial activity makes it suitable for diverse bacteriological studies. In addition to its primary antibiotic function, erythromycin gluceptate has demonstrated antitumor and neuroprotective properties, providing valuable opportunities for research in oncology and neurobiology. -
Bacterial Inhibitor
NSC-79887 is a potent nucleoside hydrolase inhibitor that demonstrates significant activity against Bacillus anthracis. This compound serves as a promising candidate for biological testing and further development aimed at countering bacterial infections. Additionally, its pharmacokinetic profile suggests that all physicochemical parameters fall within acceptable ranges, indicating potential suitability for human use. -
Antibiotic
BO-1236 is an antibiotic compound that exhibits potent antibacterial activity, particularly against Gram-negative bacteria, including Pseudomonas aeruginosa. This compound demonstrates in vitro and in vivo efficacy that is either superior to or comparable with some standard antibiotics. Additionally, BO-1236 shows stability against β-lactamase, making it a valuable tool for research applications targeting bacterial infections. -
Antibiotic
Deacetylravidomycin N-oxide is an antibiotic derived from Streptomyces ravidus S50905, primarily targeting Gram-positive bacteria while exhibiting no activity against Gram-negative strains. This compound demonstrates significant antitumor effects, particularly against P388 leukemia and methamphetamine A fibrosarcoma models. Its biological properties make it a valuable tool for research in microbiology and cancer studies. -
Antibiotic
Drimentine C is a terpenylated diketopiperazine antibiotic that targets bacterial proliferation. This compound demonstrates significant cytotoxicity, inhibiting the growth of NS-1 murine β lymphocyte myeloma cells by 63% and 98% at concentrations of 12.5 μg/mL and 100 μg/mL, respectively. Drimentine C can be utilized in research focused on antibiotic mechanisms and the evaluation of antitumor activities. -
Precursor Form
Oseltamivir acid methyl ester hydrochloride is a precursor to the neuraminidase inhibitor oseltamivir acid, which exhibits antiviral activity against influenza viruses. Upon administration, it is metabolized by carboxylesterase 1 (CES1) to yield oseltamivir acid, facilitating its therapeutic effects. This reagent is primarily utilized in research applications focused on antiviral drug development and metabolic studies involving oseltamivir. -
Antibacterial Agent
Temafloxacin hydrochloride is an orally active quinolone that functions as a broad-spectrum antibacterial agent. This compound demonstrates significant efficacy against various bacterial strains, making it suitable for the treatment of lower respiratory and genitourinary tract infections. Temafloxacin hydrochloride's well-tolerated profile further supports its potential applications in clinical research related to bacterial infection management. -
Bacterial Inhibitor
Surgumycin is a bacterial inhibitor that exhibits notable antimicrobial activity. Its mechanism involves disrupting essential cellular processes in bacteria, making it a valuable tool for studying bacterial infections and resistance mechanisms. Surgumycin is particularly useful in research applications focused on antibiotic development and the exploration of microbial pathogenesis. -
Antitumor Antibiotic
Glycocinnasperimicin D is an antitumor antibiotic that functions as a glycoside cinnamyl imide histamine derivative. It demonstrates significant antimicrobial activity against both Gram-positive and Gram-negative bacteria. Furthermore, Glycocinnasperimicin D exhibits potent cytotoxicity against leukemia L1210 cells, with an IC50 value of 2.0 μg/mL, making it a valuable compound for research in cancer biology and antibiotic efficacy studies. -
Antibiotic
Loracarbef is a synthetic beta-lactam antibiotic belonging to the carbacephem class, exhibiting potent activity against a broad range of gram-positive and gram-negative bacteria. As an orally active, second-generation cephalosporin, Loracarbef is utilized in clinical settings for the treatment of various bacterial infections. Its mechanism involves inhibiting bacterial cell wall synthesis, making it an important agent in antibiotic research and therapeutic applications. -
Anticoccidial Antibiotic
Xanthoquinodin A1 is an anticoccidial antibiotic that features a novel xanthone-anthraquinone conjugate system. This compound exhibits potent activity against Eimeria spp., making it valuable for research related to coccidiosis management in livestock and poultry. Its unique structure allows for exploration in studies of antibiotic resistance and potential therapeutic applications in veterinary medicine. -
Fluoroquinolone Antibiotic
Tosufloxacin is a fluoroquinolone antibiotic that exerts its primary action by inhibiting bacterial DNA gyrase and topoisomerase IV. It demonstrates a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria. Tosufloxacin is utilized in research applications aimed at studying bacterial infections and antibiotic resistance mechanisms. -
antibacterial
Temporin-GHc is an antimicrobial peptide primarily targeting bacterial organisms. It demonstrates significant antibacterial activity with an MBIC50 value of 6 μM and exhibits antibiofilm activity with an MBEC50 value of 25 μM at 24 hours. This compound is useful for research applications focused on bacterial inhibition and biofilm formation. -
Polypeptide Antibiotics
Polymyxin B2 Sulfate is a polypeptide antibiotic that exerts its antibacterial effects primarily against gram-negative bacteria. Its mechanism of action involves binding to lipopolysaccharide molecules on the bacterial cell membrane, leading to membrane disruption and leakage of cellular contents. This compound is valuable in antibiotic development and the treatment of drug-resistant bacterial strains. -
Antibiotic
Bactobolin is a potent antibiotic that targets multiple bacterial strains, including Escherichia coli, Salmonella, Shigella, Staphylococcus, and Bacillus subtilis, exhibiting minimum inhibitory concentrations (MICs) ranging from 0.3 to 6.25 μg/mL. In addition to its antibacterial properties, Bactobolin demonstrates antitumor activity against leukemia, with a lethal dose 50 (LD50) value ranging from 6.25 to 12.5 mg/kg. This dual functionality makes Bactobolin a valuable compound for research in both microbiology and oncology. -
Antibiotic
Carumonam disodium is a potent antibiotic that primarily targets bacterial cell wall synthesis, rendering it effective against a range of Gram-negative pathogens. This compound exhibits significant antibacterial activity, making it suitable for research applications focused on infectious disease treatment and antibiotic resistance mechanisms. However, caution is advised as Carumonam disodium has been reported to induce seizure activity in certain conditions. -
Antibacterial Agent
Moxalactam is a synthetic oxa-β-lactam antibiotic that targets bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam also effectively inhibits the production of β-lactamases, making it a valuable tool for research in antibiotic resistance and microbial pathogenesis. -
Antibiotic
Hordenine sulfate is a bioactive compound primarily known for its antibiotic properties. It exhibits significant melanin-inhibiting activity by reducing intracellular cAMP levels and decreasing melanin content. Hordenine sulfate effectively downregulates the expression of key proteins involved in melanogenesis, such as microphthalmia-associated transcription factor (MITF), tyrosinase, and tyrosinase-related proteins (TRP-1 and TRP-2). This makes Hordenine sulfate a valuable reagent for research in dermatological studies focusing on pigmentation and related disorders. -
Antibiotic
Clindamycin Sulfoxide is an active metabolite of the antibiotic clindamycin, primarily generated through S-oxidation via the cytochrome P450 isoform CYP3A4. This compound exhibits significant antibacterial activity, effectively inhibiting the growth of anaerobic bacteria, including Peptostreptococcus prevotti, Bacteroides fragilis, and Clostridium sordelli, with minimal inhibitory concentration (MIC) values of 2 mg/L, 2 mg/L, and 1 mg/L, respectively. Clindamycin sulfoxide serves as a valuable tool for research applications focused on antibiotic efficacy and resistance mechanisms. -
Antibacterial Agent
Antofloxacin hydrochloride is a broad-spectrum 8-amino-fluoroquinolone that functions as an antibacterial agent. It demonstrates potent activity against gyrA mutation-positive Helicobacter pylori strains, notably the Asn87 mutant, where it surpasses the efficacy of levofloxacin. Additionally, Antofloxacin hydrochloride acts as a weak, reversible inhibitor of CYP1A2, making it a valuable reagent for studying infections caused by a variety of bacterial species. -
Peptide Antibiotic
A83586C is a novel peptide antibiotic that specifically targets Gram-positive bacteria. It exhibits potent antibacterial activity, making it a valuable tool for studying bacterial infections and developing new therapeutic strategies. Its unique mode of action allows researchers to explore mechanisms of resistance and efficacy in various biological contexts. -
Macrolide Antibiotic
Macrosphelide A is a macrolide antibiotic that exhibits potent antimicrobial activity against a range of fungal pathogens, including ascomycetes, basidiomycetes, and oomycetes. It effectively inhibits the growth of all tested Gram-positive bacteria, including the clinically relevant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of ≤500 μg/mL. This compound is valuable for research applications aimed at exploring new antibacterial and antifungal therapeutics. -
Antibiotic
Antibiotic A40104A is an antimicrobial agent that targets bacterial cell wall synthesis. It demonstrates significant antibacterial activity against a broad spectrum of gram-positive and gram-negative organisms. This compound is suitable for use in microbiological research, including studies on antibiotic resistance mechanisms and the development of new antibacterial therapies. -
Antibiotic
Dihydrostreptomycin (DHSM) is an aminoglycoside antibiotic that primarily targets Gram-negative bacteria. It demonstrates significant antibacterial activity and is commonly utilized in research focused on the mechanisms of antibiotic resistance. Due to its ototoxic effects, which can cause irreversible damage to inner ear hair cells, it serves as a valuable model for investigating hearing loss and its underlying biological pathways. -
Antibiotic
Nanaomycin αA is an antibiotic known for its antimicrobial activity. Isolated from the fermentation broth of Streptomyces hebeiensis, this compound exhibits efficacy against various bacterial strains. Its unique properties make it valuable for research applications in microbiology and the development of new antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 221 is a potent inhibitor specifically targeting Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). This compound exhibits significant antibacterial activity, demonstrating effectiveness against resistant strains. Additionally, Antibacterial Agent 221 shows pronounced cytotoxicity against human LO2 and HepG2 cells, making it a valuable tool for research in antimicrobial resistance and cytotoxic effects. -
Antibiotic
Quinaldopeptin is a quinomycin antibiotic derived from the culture of Streptoverticillium album that exhibits significant activity against Gram-positive bacteria and anaerobic pathogens. In addition to its antibacterial properties, Quinaldopeptin demonstrates potent cytotoxic effects on cultured B16 melanoma cells. This compound is valuable for research applications focusing on antimicrobial resistance and cancer therapeutics. -
Antibacterial Agent
Nifurtoinol is a nitrofuran-derived antibiotic that exerts antibacterial activity. It is primarily investigated for its effectiveness against urinary tract infections, making it a valuable compound for research in infectious disease studies and antibiotic development.
