Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity. -
Monoterpene alcohol
Fenchyl alcohol is a monoterpene alcohol known for its antifungal properties. It effectively inhibits the formation of biofilms and hyphae in Candida albicans, making it valuable for studies on fungal infections. Additionally, Fenchyl alcohol demonstrates a significant inhibitory effect on rumen microbial activity in ruminants such as sheep and deer, aiding research in gastrointestinal microbiology. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Antifungal Agent
Sulbentine is an azole antifungal agent that exhibits both fungistatic and fungicidal activities. It serves as a locally acting antimycotic in vivo, making it valuable for treating a range of fungal infections. Sulbentine is commonly utilized in research applications focused on antifungal mechanisms and drug efficacy studies. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
SDHI
Penflufen is a potent succinate dehydrogenase inhibitor (SDHI) that targets the mitochondrial respiratory chain. This compound demonstrates broad-spectrum antifungal activity, effectively combating a variety of fungal diseases such as potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanuts. Penflufen is valuable for research applications in plant pathology and agricultural disease management. -
Antifungal Agent
Antifungal agent 18 is an antifungal agent that acts by disrupting fungal cell wall integrity through targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. It exhibits broad-spectrum antifungal activity against major human fungal pathogens, demonstrating efficacy in both in vitro and in vivo studies. This compound is suitable for research involving invasive fungal pathogens and cutaneous dermatophytes, providing valuable insight into fungal pathogenesis and potential therapeutic interventions. -
Antifungal Agent
4,6-Dimethoxysalicylaldehyde is an antifungal agent that exhibits significant activity against Candida albicans and moderate activity against Saccharomyces cerevisiae. This compound is utilized in research focusing on antifungal mechanisms and potential therapeutic applications for fungal infections. Its unique structure and activity profile make it a valuable tool for studying the efficacy of antifungal treatments. -
Antiacid/Antiulcer Agent
Magnesium silicate primarily acts as an antacid and antiulcer agent. This compound, comprised of magnesium oxide and silicon dioxide, offers effective relief from gastric discomfort and acidity. Additionally, magnesium silicate serves various research applications, including the development of food additives and the exploration of its piezoelectric properties. Its diverse capabilities also extend to use as a deodorant, decolorizing agent, and antifungal agent in biological systems. -
Antifungal Agent
Fosravuconazole L-lysine ethanolate, a prodrug of Ravuconazole, acts as an orally bioavailable broad-spectrum antifungal agent. It demonstrates significant efficacy against various fungal infections, making it a valuable tool for research on candidiasis, onychomycosis, and parasitemia. This compound is instrumental in exploring antifungal therapies and evaluating treatment outcomes in fungal-related diseases. -
Fungicide
Kresoxim-methyl is a Strobilurin-based fungicide that primarily targets the cytochrome bc1 complex, inhibiting respiration at complex III. It demonstrates high affinity binding to yeast complex III with an apparent Kd of 0.07 μM. This compound is widely utilized in agricultural research to assess its antifungal activity and its mechanisms in pathogen resistance management. -
jRdRp Inhibitopr
Kulactone is a natural bioflavonoid that functions as an inhibitor of the RNA-dependent RNA polymerase (jRdRp). This compound demonstrates significant antifungal, antibacterial, and antiplasmodial activities, making it a valuable tool in infectious disease research. Additionally, Kulactone is noted for its inability to cross the blood-brain barrier, which may limit its central nervous system effects and enhance its application in peripheral infections. -
Fungicide
Dimethomorph is a fungicide classified as a sterol biosynthesis inhibitor. It effectively disrupts fungal cell wall formation, thereby impeding fungal growth. Additionally, Dimethomorph has been shown to inhibit androgen receptor (AR) activity in MDA-kb2 cells with an IC20 value of 0.263 µM, making it relevant for studies on hormone receptor signaling and fungal pathogenesis. -
Antifungal Agent
D75-4590 is a pyridobenzimidazole derivative that functions as a β-1,6-glucan synthesis inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for investigating fungal biology and potential therapeutic applications. Its mechanism of action may aid in the development of novel antifungal strategies and enhance understanding of cell wall biosynthesis in pathogenic fungi. -
Antifungal Agent
1-Eicosanol, a long-chain fatty alcohol, functions as an antifungal agent by inhibiting mycelial growth of pathogens such as Alternaria solani and Botrytis cinerea. Derived from natural sources including the leaves of Leea indica and produced by Bacillus velezensis ZJ1, this compound is particularly relevant for research focused on tomato early blight and gray mold. Its applications extend to understanding fungal interactions and exploring biocontrol methods in agricultural settings. -
Fungicide Agent
Faltan is a dicarboximide fungicide that primarily targets fungal pathogens to inhibit their growth. It is commonly employed in the agricultural industry for the protection of vines and various vegetable crops. Additionally, Faltan exhibits cytotoxic effects on human bronchial epithelial cells, making it a valuable compound for research in both plant protection and cellular biology applications. -
Fungicide
Isoprothiolane is a potent blast fungicide that targets fungal growth during the penetration and development phases of infecting hyphae. It exhibits antifungal and anti-inflammatory properties, making it suitable for various agricultural applications. Additionally, Isoprothiolane has been shown to modulate lipid metabolism by reducing serum phospholipid and total lipid concentrations, contributing to research in fatty liver conditions. Its versatile biological activities support its use in both plant protection and metabolic studies. -
Antibiotic
Roridin E is an antibiotic that exhibits cell-inhibiting and fungicidal properties. It is known for its efficacy in combating various fungal infections and serves as a valuable tool in antimicrobial research. Roridin E's mechanism of action, which involves disrupting cellular processes in target organisms, makes it suitable for studies aimed at understanding fungal pathogenesis and potential therapeutic interventions. -
Fungicide
Flutriafol is a triazole fungicide that inhibits the enzyme lanosterol 14α-demethylase, disrupting ergosterol biosynthesis in fungal cell membranes. It exhibits broad-spectrum antifungal activity, making it effective against various plant pathogens. Flutriafol is commonly utilized in agricultural research and crop protection studies to manage fungal diseases and enhance plant health. -
antifungal agent
Abafungin is an antifungal agent that functions by inhibiting the transmethylation at the C-24 position of the sterol side chain, a reaction catalyzed by the enzyme sterol-C-24-methyltransferase. This mechanistic action disrupts ergosterol biosynthesis, which is crucial for fungal cell membrane integrity. Abafungin is used in research to study fungal pathogenesis and to develop new antifungal therapies. -
Antifungal Agent
6-Chloro-7-deazapurine-β-D-riboside functions as an antifungal agent through its nucleoside derivative structure. It demonstrates inhibitory activity against various plant pathogenic fungi, making it a valuable tool for studies in fungal biology and plant protection. This compound may be utilized in research focused on antifungal mechanisms and the development of novel therapeutic strategies in agriculture. -
Antifungal Antibiotic Agent
Candicidin is a polyene antifungal antibiotic agent that functions by binding to ergosterol in fungal cell membranes, leading to increased permeability and cell death. It exhibits potent antifungal activity against a range of pathogenic fungi. Candicidin is primarily used in research applications focused on fungal infections and the mechanisms of antifungal resistance. -
Fungicide
Quinoxyfen is a systemic fungicide that primarily targets the growth and development of powdery mildew pathogens. It exhibits significant antifungal activity by inhibiting the biosynthesis of sterols, which are essential for fungal cell membrane integrity. Quinoxyfen is widely utilized in agricultural research for its effectiveness in controlling powdery mildew in various crops, making it an important agent in plant disease management studies. -
Antibiotic
Polyhexamethyleneguanidine hydrochloride is a cationic polymer known for its broad-spectrum antimicrobial activity. It primarily exerts its antibacterial effects by interacting with bacterial and fungal cell membranes, leading to disruption of membrane integrity. This compound is valuable in research related to disinfection, water treatment, and agricultural pesticides. -
Fungal Inhibitor
Dihydrochelerythrine is a natural compound derived from Corydalis yanhusuo, primarily functioning as a fungal inhibitor. This compound exhibits notable antifungal activity, making it a valuable reagent for research applications focused on mycology and the study of fungal infections. Its properties may contribute to the development of novel antifungal therapies. -
Fungicide
Flutolanil is a broad-spectrum fungicide that primarily targets mitochondrial Complex II, inhibiting mycelial oxygen consumption and succinate dehydrogenase activity. This compound is effective against various fungal pathogens, making it valuable for managing plant diseases. Additionally, studies indicate that prolonged exposure to Flutolanil may lead to endocrine disruption and reproductive disorders in zebrafish, highlighting its relevance in ecotoxicology research. -
Fungal Inhibitor
Cauloside A, a saponin derived from the roots of Dipsacus asper, serves as a potent fungal inhibitor. It exhibits significant antifungal activity, making it a valuable reagent for research focused on fungal pathogenesis and therapeutic interventions. Its effectiveness in combating various fungal strains positions Cauloside A as a crucial tool in the study of antifungal mechanisms and the development of new antifungal agents. -
Antifungal Agent
Isopropyl ferulate is a naturally occurring compound known for its antifungal properties. It acts by inhibiting fungal growth, making it a valuable candidate for the development of antifungal agents. Additionally, isopropyl ferulate is utilized in pharmaceutical formulations and cosmetic products due to its antioxidant activity, highlighting its versatility in various biological applications. -
Fungicide
Metalaxyl-M, also known as (R)-Metalaxyl, is a selective inhibitor of fungal RNA polymerase. It demonstrates potent fungicidal activity by disrupting the synthesis of fungal ribosomal RNA. Additionally, Metalaxyl-M is useful for inducing inflammation in hepatocytes and modulating tryptophan metabolism. Its applications extend to ecotoxicology studies, making it a valuable reagent for investigating fungal resistance and environmental impacts. -
Fungicide
Picoxystrobin is a strobilurin fungicide that targets mitochondrial respiration to control a broad spectrum of plant diseases. This compound is known for its potent activity against fungal pathogens, making it invaluable in agricultural research. Additionally, studies have shown that Picoxystrobin exhibits high toxicity in zebrafish embryos, leading to developmental abnormalities, oxidative stress, and immunotoxic effects, underscoring its relevance in ecotoxicological assessments. -
Antiplasmodial Agent
Neocryptolepine is a potent antiplasmodial agent, exhibiting significant activity against Plasmodium spp. Additionally, it demonstrates antibacterial effects, particularly against Gram-positive bacteria with a minimum inhibitory concentration (MIC) below 100 μg/mL, as well as antifungal properties. This compound serves as a valuable tool in research focused on malaria treatment and the development of novel antimicrobial therapies. -
Antifungal Agent
(+)-Columbianetin acetate functions as an antifungal agent with significant biological activity. This compound is an isomer of Columbianetin, a phytoalexin found in celery (Apium graveolens), which is linked to enhanced resistance against pathogens during storage. Research applications include the study of its antifungal and anti-inflammatory properties, making it a valuable tool for exploring plant defense mechanisms and developing new antifungal therapies. -
Fungus Metabolite
Averantin is a fungal metabolite derived from Cercospora arachidicola, serving as a precursor in the biosynthesis of aflatoxin B1. This compound is integral to the study of fungal metabolism and can be utilized to explore the biosynthetic pathways of mycotoxins. Researchers can leverage Averantin to investigate its role and impact in various biological processes related to fungal development and toxin production. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
Antineoplastic Agent
Protoneogracillin is a furostanol glycoside with demonstrated antineoplastic properties. It exhibits cytotoxic effects on K562 cancer cells with an IC50 value of 6.6 μM, indicating significant potential for cancer research. Additionally, Protoneogracillin has anti-fungal activity against the plant pathogenic fungus Pyricularia oryzae, with an MMDC of 94.0 μM, suggesting broader applications in phytopathological studies. -
Antifungal
Flutrimazole is an imidazole compound that exhibits antifungal and anti-inflammatory activity, primarily targeting fungal cell membrane synthesis. This reagent is effective in addressing topical fungal infections that involve inflammatory responses, making it a valuable tool for research in dermatophytoses. Despite limited transdermal penetration, Flutrimazole is useful for elucidating the mechanisms underlying fungal infections and developing targeted therapies. -
Antifungal Agent
Sodium methylparaben, 99% (Sodium methyl 4-hydroxybenzoate) functions as an effective antifungal agent. It exhibits inhibitory activity against various fungal strains, making it valuable in pharmaceutical and cosmetic formulations. Sodium methylparaben is also utilized in biochemical research to explore mechanisms of fungal resistance and antimicrobial efficacy. -
Drug Scaffold
Isoxazole is a five-membered heterocyclic compound that serves as a drug scaffold, primarily targeting BET bromodomains. It has demonstrated efficacy in enhancing β-cell function in diabetic mouse models and exhibits a wide range of biological activities, including antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, and anti-diabetic properties. Isoxazole and its derivatives, such as bicyclic and tricyclic forms, have shown potential as inhibitors of HSP90 and selective multidrug resistance protein (MRP1), respectively, making them valuable for various therapeutic applications in chemical research. -
PI-3 Virus Inhibitor
Tetrahydroepiberberine is an isoquinoline alkaloid derived from Corydalis impatiens. It exhibits significant antifungal properties and demonstrates selective inhibitory effects against the PI-3 virus. This compound is valuable for research applications focused on viral pathogenesis and the development of antiviral therapeutics. -
Fungicides
HWY-289 is a semisynthetic protoberberine derivative targeting phytopathogenic fungi. It exhibits broad-spectrum activity, particularly effective against Botrytis cinerea with an EC50 of 1.34 μg/mL. HWY-289 alters mycelial morphology and disrupts cellular internal structure, leading to reduced ATP content and ATPase activity, as well as inhibition of key enzymes within the TCA cycle. These properties make HWY-289 a valuable tool for research in fungal physiology and plant pathology. -
Bactericide
3-Nitrobenzoic acid is a bactericidal compound with significant antibacterial and antifungal properties. It effectively targets and eliminates various bacterial strains and fungi, making it a valuable tool in microbial research. Additionally, certain bacteria, such as Pseudomonas, and fungi, including white rot fungi, can degrade or reduce 3-Nitrobenzoic acid into aldehydes and alcohols, providing insights into metabolic pathways and bioremediation applications. -
Antifungal
5-n-Heneicosylresorcinol is an n-alkyl(enyl)resorcinol derived from cereal products found in Colombia, exhibiting significant antifungal properties. This compound demonstrates potential efficacy against various fungal strains, making it valuable for research focused on antifungal agents and their mechanisms of action. Its unique structure and biological activity facilitate investigations into the development of novel therapeutic applications in combating fungal infections. -
Tyrosinase Inhibitor
Geranic acid is a tyrosinase inhibitor with demonstrated antifungal properties, exhibiting an IC50 range of 0.14-2.3 mM against mushroom tyrosinase. This compound significantly reduces the viability of human pancreatic cancer cells and B-lymphoma cells, highlighting its potential in cancer research. Additionally, geranic acid effectively inhibits the mycelial growth of maize pathogens such as Colletotrichum graminicola and Fusarium graminearum. It serves as a valuable reagent for studies on fungal infections, pancreatic cancer, and B-lymphoma. -
Antifungal Agent
Pivalophenone (2,2-Dimethylpropiophenone) is a dimethylated compound that serves as an effective antifungal agent. It demonstrates significant inhibitory activity against E. floccosum C 114, with a minimum inhibitory concentration (MIC) of 50 µg/mL. This compound can be utilized in research applications focused on fungal infections and the development of antifungal therapies. -
Antifungal Agent
Eleutherol is a naphthalene derivative derived from E. americana, exhibiting significant antifungal properties. It effectively targets various yeast species, including Candida albicans, C. tropicalis, Saccharomyces cerevisiae, and Cryptococcus neoformans, with minimum inhibitory concentration (MIC) values ranging from 7.8 µg/mL to 250 µg/mL. Additionally, Eleutherol inhibits α-glucosidase activity, presenting an IC50 greater than 1.00 mM, indicating its potential for further research in antifungal applications and enzyme inhibition studies. -
Antifungal Agent
NP-BTA is an allosteric inhibitor of glutaminyl-tRNA synthetase (GlnRS), demonstrating significant antifungal activity. It exhibits an MIC50 of 6.25 μM against Candida albicans, making it a valuable tool for research applications focused on fungal infections. Its mechanism contributes to the understanding of tRNA synthetase inhibition in the context of antifungal drug development. -
Fungal Inhibitor
Xanthyletin is a coumarin compound derived from Stauranthus perforatus that acts primarily as a fungal inhibitor. It exhibits notable anti-tumor and antibacterial activities, making it valuable for various research applications in microbiology and cancer studies. Additionally, Xanthyletin effectively inhibits the symbiotic fungus cultivated by leaf-cutting ants, further highlighting its potential in ecological and agricultural research. -
Chalcone Derivative
4'-Hydroxy-2,4-dimethoxychalcone is a chalcone derivative primarily derived from the red herbal resin of Dracaena cochinchinensis. This compound exhibits a diverse array of biological activities, including antimalarial, antiprotozoal, antibacterial, and antifungal effects. Due to its broad-spectrum properties, it serves as a valuable tool in pharmaceutical research and development, particularly in the exploration of novel antimicrobial and antiparasitic therapies. -
Antifungal Agent
Thifluzamide is a potent antifungal agent that targets the ubiquinone-binding site of mitochondrial complex II, effectively inhibiting fungal respiration. This compound demonstrates significant activity against Basidiomycota pathogens, including genera such as Rhizoctonia, Ustilago, and Puccinia, making it valuable in studies related to wheat sharp eyespot. Additionally, Thifluzamide plays a dual role in lipid metabolism regulation by decreasing fatty acid synthase activity and enhancing carnitine palmitoyltransferase-I activity, leading to reduced cholesterol and triglyceride levels. However, caution is advised due to its potential hepatotoxic effects observed in zebrafish models and the risk of developmental toxicity.
